Volume 20 Issue 5
May  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(5): 882-885
TANG Ting, ZHANG Qiang, WANG Xiang, HE Li-yun, ZHANG Wen-bin. Effect of improved continuous nursing on surgical stress and immune function in patients with gastric cancer after laparoscopic distal gastrectomy[J]. Chinese Journal of General Practice, 2022, 20(5): 882-885. doi: 10.16766/j.cnki.issn.1674-4152.002478
Citation: TANG Ting, ZHANG Qiang, WANG Xiang, HE Li-yun, ZHANG Wen-bin. Effect of improved continuous nursing on surgical stress and immune function in patients with gastric cancer after laparoscopic distal gastrectomy[J]. Chinese Journal of General Practice, 2022, 20(5): 882-885. doi: 10.16766/j.cnki.issn.1674-4152.002478
shu

Effect of improved continuous nursing on surgical stress and immune function in patients with gastric cancer after laparoscopic distal gastrectomy

doi: 10.16766/j.cnki.issn.1674-4152.002478
  • 1.

    Central Operating Room, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China

Funds:

 W2017ZWS05

  • Received Date: 2021-04-18
    Available Online: 2022-09-05
    Abstract
  •   Objective  To analyze the impact of improved continuous nursing based on the concept of accelerated rehabilitation surgery on the surgical stress and immune function of gastric cancer patients after laparoscopic distal gastrectomy.  Methods  From June 2018 to June 2020, 98 patients with gastric cancer who underwent laparoscopic distal gastrectomy were selected from the First Affiliated Hospital of Xinjiang Medical University. They were divided into the observation group (49 cases) and control group (49 cases) according to the random number table method. The control group was given conventional nursing interventions, whereas the observation group was given improved continuous nursing based on the concept of accelerated rehabilitation surgery. Changes of stress function indexes at different stages and immune function indexes of both groups were compared after surgery.  Results  The levels of inflammatory mediators (IL-6, IL-8 and IL-10) of both groups on the 1st, 4th and 7th day after the operation increased compared with those before the operation, and the levels of IL-6 and IL-8 of the observation group were significantly lower than those of the control group (all P < 0.05). The two groups of patients had a decrease in CD4+, CD8+ and CD4+/CD8+ levels on the 1st and 4 th day after operation, while CD4+ increased on the 7th day after operation (all P < 0.05), and there was no significant difference between the two groups (P > 0.05). The levels of IgA, IgG and IgM on the 1st and 4th days decreased, and the difference between groups was statistically significant (all P < 0.05). On the 7th day, the levels of IgA, IgG and IgM basically returned to the preoperative level. The levels of IgA and IgG of the observation group on days 1, 4 and 7 were higher than those of the control group, and the difference between groups was statistically significant (all P < 0.05).  Conclusion  The improved continuous nursing based on the concept of accelerated rehabilitation surgery can effectively improve the clinical effect of gastric cancer patients undergoing laparoscopic distal gastrectomy, reduce their stress inflammatory response, promote the recovery and improvement of their immune function to a certain extent and promote their recovery after surgery.

     

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