Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease

MA Shou-liang; YANG Wen-ming; HAN Bing; LI Yue-yue; XU Zhi-hao; SONG Cheng-wei; HAN Hui

doi:10.16766/j.cnki.issn.1674-4152.002485

Volume 20 Issue 6

Jun. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(6): 910-913

MA Shou-liang, YANG Wen-ming, HAN Bing, LI Yue-yue, XU Zhi-hao, SONG Cheng-wei, HAN Hui. Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease[J]. Chinese Journal of General Practice, 2022, 20(6): 910-913. doi: 10.16766/j.cnki.issn.1674-4152.002485

Citation:

MA Shou-liang, YANG Wen-ming, HAN Bing, LI Yue-yue, XU Zhi-hao, SONG Cheng-wei, HAN Hui. Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease[J]. Chinese Journal of General Practice, 2022, 20(6): 910-913. doi: 10.16766/j.cnki.issn.1674-4152.002485

Citation:

MA Shou-liang, YANG Wen-ming, HAN Bing, LI Yue-yue, XU Zhi-hao, SONG Cheng-wei, HAN Hui. Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease[J]. Chinese Journal of General Practice, 2022, 20(6): 910-913. doi: 10.16766/j.cnki.issn.1674-4152.002485

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Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease

doi: 10.16766/j.cnki.issn.1674-4152.002485

MA Shou-liang^{1, 2}
, YANG Wen-ming^{1, 2
,
,}
, HAN Bing³
, LI Yue-yue³
, XU Zhi-hao³
, SONG Cheng-wei³
, HAN Hui^{1, 2}

1.
Encephalopathy Center, the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui 230031, China

Funds:

81973825

2020ZY141-410901

1804h08020243

Received Date: 2021-09-08
Available Online: 2022-09-21

Abstract

Abstract

Objective To observe the effect of removing blood stasis and resolving phlegm on the nerve function in patients with Wilson ' s disease. Methods A total of 60 Wilson's disease patients with phlegm and blood stasis who were hospitalised in the Encephalopathy Center of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2019 to June 2021 were treated for the research. These patients were randomly divided into treatment group and comparison group according to the random number table method, with 30 patients in each group. The treatment comprised two courses. During the treatment, Wilson ' s disease neurological function score, clinical efficacy and 24 h urine copper in the two groups were observed. Results At the end of 2 courses of treatment, the neurological function scores of the treatment and comparison group [(25.63±9.06) points and (57.13±12.03) points] were lower than those before treatment [(64.03±11.41) points and (66.40±13.27) points, all P < 0.05]. At the end of 2 courses of treatment, the neurological function score of the treatment group was lower than that of the comparison group (P < 0.05). The clinical efficacy of the treatment group was more significant (93.3% vs. 70.0%, χ²=5.455, P=0.020). At the end of 2 courses of treatment, the 24 h urinary copper values in the treatment and comparison groups [(1 690.40±369.90) μg/24 h and (1 376.75±311.91) μg/24 h] were higher than those before treatment [(202.33±38.11) μg/24 h and (206.66±38.38) μg/24 h, all P < 0.01]. The urine copper value in the treatment group was significantly higher than that in the comparison group after treatment (P < 0.05). Conclusion Removing blood stasis and resolving phlegm can significantly improve the neurological function of patients with Wilson's disease, the clinical efficacy and the quality of life of patients.
- Removing stasis and resolving phlegm,
- Hepatolenticular degeneration,
- Nerve function

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References(24)

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Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease

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Effects of removing blood stasis and resolving phlegm on the nerve function in Wilson's Disease

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