Volume 20 Issue 6
Jun.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(6): 1036-1040
MAO Jing, HONG Yong-feng, FENG Xiao-jun, TANG Xiao-xiao, ZHANG Jin-niu, KAN Xiu-li, SHEN Xian-shan, WU Jian-xian. Effect of repetitive transcranial magnetic stimulation of different frequencies on the cognition and movement of stroke patients[J]. Chinese Journal of General Practice, 2022, 20(6): 1036-1040. doi: 10.16766/j.cnki.issn.1674-4152.002518
Citation: MAO Jing, HONG Yong-feng, FENG Xiao-jun, TANG Xiao-xiao, ZHANG Jin-niu, KAN Xiu-li, SHEN Xian-shan, WU Jian-xian. Effect of repetitive transcranial magnetic stimulation of different frequencies on the cognition and movement of stroke patients[J]. Chinese Journal of General Practice, 2022, 20(6): 1036-1040. doi: 10.16766/j.cnki.issn.1674-4152.002518
shu

Effect of repetitive transcranial magnetic stimulation of different frequencies on the cognition and movement of stroke patients

doi: 10.16766/j.cnki.issn.1674-4152.002518

  • Department of Rehabilitation Medicine, the Second Hospital of Anhui Medical University, Hefei, Anhui 230601, China

Funds:

 202004j07020040

 2021zhyx-C50

  • Received Date: 2022-02-11
    Available Online: 2022-09-21
    Abstract
  •   Objective  To compare the effects of different intensities of repetitive transcranial magnetic stimulation (rTMS) on cognition and movement in patients with cognitive impairment after stroke.  Methods  A total of 63 stroke patients who were hospitalised in the Department of Rehabilitation Medicine of the Second Hospital of Anhui Medical University from October 2018 to March 2020 were included. They were randomly divided into three groups (22 cases in control group, 20 cases in low-frequency group and 21 cases in high-frequency group). The control group was treated with routine rehabilitation training. One Hz rTMS treatment was added to the low frequency group. Ten Hz rTMS treatment was added to the high frequency group. The duration of the above treatment was three weeks. The patients were evaluated using the Montreal cognitive assessment (MoCA), mini-mental state examination (MMSE), Fuel-Meyer assessment(FMA) and modified barthel index (MBI) before and after treatment.  Results  The scores of MOCA, MMSE, FMA and MBI in the three groups were significantly higher than those before treatment (all P < 0.05). After treatment, the total scores of the high-frequency and low-frequency groups were better than those of the control group (all P < 0.05). Before and after treatment, there were significant differences in MOCA difference [(6.71±1.76) points vs. (4.85±2.03) points], MMSE difference [(3.05±1.07) points vs. (2.10±1.02) points], FMA difference [(7.52 ± 2.36) points vs. (5.30±3.25) points] and MBI difference [(10.00±4.74) points vs. (6.25±3.58) points] between high frequency group and low frequency group (all P < 0.05). The scores of visual space, executive function and orientation ability in the high-frequency and low-frequency groups before and after treatment were statistically significant (all P < 0.05). There was a significant positive correlation between the difference of MOCA and FMA after treatment (high-frequency group r=0.906, low-frequency group r=0.902, control group r=0.886, all P < 0.01).  Conclusion  Routine rehabilitation training combined with high-frequency or low-frequency rTMS can effectively improve patients ' cognition, movement and self-care ability, amongst which routine rehabilitation combined with high-frequency rTMS has the best effect. The cognitive and movement functions of stroke patients promote each other.

     

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