Comparison of enteral feeding status of extremely low birth weight infant of different gestational ages

KE Ruo; CHEN Si-si; ZHOU Rui-xi; HU Ying-ying

doi:10.16766/j.cnki.issn.1674-4152.002595

Volume 20 Issue 8

Aug. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(8): 1353-1356

KE Ruo, CHEN Si-si, ZHOU Rui-xi, HU Ying-ying. Comparison of enteral feeding status of extremely low birth weight infant of different gestational ages[J]. Chinese Journal of General Practice, 2022, 20(8): 1353-1356. doi: 10.16766/j.cnki.issn.1674-4152.002595

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KE Ruo, CHEN Si-si, ZHOU Rui-xi, HU Ying-ying. Comparison of enteral feeding status of extremely low birth weight infant of different gestational ages[J]. Chinese Journal of General Practice, 2022, 20(8): 1353-1356. doi: 10.16766/j.cnki.issn.1674-4152.002595

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Comparison of enteral feeding status of extremely low birth weight infant of different gestational ages

doi: 10.16766/j.cnki.issn.1674-4152.002595

Department of Neonatology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funds:

LQ20H040002

Received Date: 2021-11-02

Abstract

Abstract

Objective To investigate and compare the differences in enteral feeding status amongst extremely low birth weight infants (ELBWI) of different gestational ages. Methods A total of 120 ELBWI patients admitted to the neonatal intensive care unit (NICU) of the Second Affiliated Hospital of Wenzhou Medical University from January 2019 to December 2020 were selected as the research subjects. According to the gestational age, the children were divided into the gestational age < 28 weeks group (n=68) and the gestational age ≥28 weeks group (n=52). Enteral feeding status and enteral nutritional intolerance (FI) were compared between the two groups. Results The amount of milk in the first 3 weeks after birth in the gestational age < 28 weeks group was significantly lower than that in the gestational age ≥28 weeks group (t=-2.208, -13.148, -27.781, all P < 0.05). The time to reach sufficient enteral feeding for the first time and the total length of hospital stay in the gestational age < 28 weeks group were significantly higher than those in the gestational age ≥28 weeks group (t=8.459, 22.654, all P < 0.05). The rate of weight gain after birth weight recovery and weight at discharge were significantly lower than those in the gestational age ≥28 weeks group (t=-10.034, -12.042, all P < 0.05). During hospitalisation, the incidence of bronchopulmonary dysplasia, necrotizing enterocolitis, invasive mechanical ventilation, ibuprofen use within 2 weeks and antibiotic use >2 weeks in gestational age < 28 weeks were significantly higher than those in gestational age≥28 weeks (χ²=7.169, 6.114, 4.544, 4.834, 4.488, all P < 0.05). The duration of FI, the incidence of FI within 2 weeks after birth and the recurrence rate of FI in gestational age < 28 weeks were significantly higher than those of gestational age ≥28 weeks (all P < 0.05). Conclusion The enteral feeding status of ELBWI at different gestational ages varies greatly. Compared with ELBWI of ≥28 weeks of gestational age, ELBWI of < 28 weeks of gestational age have higher FI recurrence rate, poor feeding tolerance and slow growth and development.
- Extremely low birth weight infant,
- Gestational age,
- Enteral feeding

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Comparison of enteral feeding status of extremely low birth weight infant of different gestational ages

doi: 10.16766/j.cnki.issn.1674-4152.002595