Volume 20 Issue 9
Sep.  2022
Turn off MathJax
Article Contents
JIN Shan, FANG Xiang, YANG Wen-ming, XIE Dao-jun. Characteristics of emotional behaviour and social life ability in children with cerebral Wilson's disease[J]. Chinese Journal of General Practice, 2022, 20(9): 1455-1457. doi: 10.16766/j.cnki.issn.1674-4152.002621
Citation: JIN Shan, FANG Xiang, YANG Wen-ming, XIE Dao-jun. Characteristics of emotional behaviour and social life ability in children with cerebral Wilson's disease[J]. Chinese Journal of General Practice, 2022, 20(9): 1455-1457. doi: 10.16766/j.cnki.issn.1674-4152.002621

Characteristics of emotional behaviour and social life ability in children with cerebral Wilson's disease

doi: 10.16766/j.cnki.issn.1674-4152.002621
Funds:

 81973825

 KJ2019A0457

 2008085MH264

  • Received Date: 2021-12-27
    Available Online: 2022-11-29
  •   Objective  To clarify the characteristics of emotional behaviour and social life ability of children with cerebral Wilson's disease (WD), to find concealed neuropsychological damage in time, to adopt more targeted individualised intervention programs and correct abnormal emotional behaviour, and to improve the social life ability of children.  Methods  Thirty children with cerebral WD in the Encephalopathy Center of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2019 to December 2020 served as the observation group. Thirty healthy school-age children served as the control group in the same period. The characteristics of emotional behaviour and social life ability of 30 WD children and 30 normal children were assessed by Achenbach children's behaviour scale and infant junior middle school students' social life ability scale. The differences between WD children and normal children were analysed.  Results  The scores of aggression, poor communication, social withdrawal, and violation of discipline in the cerebral WD group were 8.0(7.0, 9.0) points, 4.0(3.0, 5.0) points, 3.0(3.0, 4.0) points, 4.0(3.0, 5.0) points and the control group were 6.0(4.0, 7.0) points, 3.0(1.8, 3.0) points, 1.0(1.0, 2.0) points, 1.0(1.0, 2.0) points, respectively. A significant difference existed between the two groups (all P < 0.05). In the assessment of social ability, no significant difference existed between the two groups (P>0.05). A significant difference existed in the scores of independent life, sports, communication, collective activities, and self-management (all P < 0.05).  Conclusion  Significant personality changes, irritability, decreased social ability and other emotional behaviour, and living ability abnormalities exist in children with cerebral WD. In addition to the improvement in clinical symptoms, the treatment of such patients should also pay attention to mental and psychological rehabilitation so that they can have more complete spiritual and psychological functions and good social adaptability.

     

  • loading
  • [1]
    GUINDI M. Wilson disease[J]. Semin Diagn Pathol, 2019, 36(6): 415-422. doi: 10.1053/j.semdp.2019.07.008
    [2]
    董文文, 杨文明, 董婷, 等. 应用注意网络测试研究肝豆状核变性患者注意损害[J]. 中华全科医学, 2019, 17(12): 1998-2000, 2086. doi: 10.16766/j.cnki.issn.1674-4152.001111

    DONG W W, YANG W M, DONG T, et al. Study on the attentional damage of Wilson's disease patients by attentional network test[J]. Chinese Journal of General Practice, 2019, 17(12): 1998-2000, 2086. doi: 10.16766/j.cnki.issn.1674-4152.001111
    [3]
    杨旭. 肝豆状核变性诊断指标的意义及其局限性[J]. 中华肝脏病杂志, 2017, 25(12): 881-885. doi: 10.3760/cma.j.issn.1007-3418.2017.12.001

    YANG X. The diagnostic value and limits of diagnostic parameters for Wilson' s disease[J]. Chinese Journal of Hepatology, 2017, 25(12): 881-885. doi: 10.3760/cma.j.issn.1007-3418.2017.12.001
    [4]
    陆昶谋, 何梅, 张玲, 等. 6~11岁儿童行为问题特征分析[J]. 教育观察, 2019, 8(33): 3-5. https://www.cnki.com.cn/Article/CJFDTOTAL-JYGN201933002.htm

    LU C M, HE M, ZHANG M, et al. Analysis of characteristics of 6-11 years old children' s behavioral problems[J]. Survey of Education, 2019, 8(33): 3-5. https://www.cnki.com.cn/Article/CJFDTOTAL-JYGN201933002.htm
    [5]
    柯晓燕. 儿童青少年心理障碍评估与诊断要点[J]. 中国实用儿科杂志, 2017, 32(4): 249-252. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK201704004.htm

    KE X Y. Main points of assessment and diagnosis of children and adolescents with mental disorders[J]. Chinese Journal of Practical Pediatrics, 2017, 32(4): 249-252. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK201704004.htm
    [6]
    方明娟, 许亚运, 杨任民, 等. 肝豆状核变性患者心理弹性水平及影响因素[J]. 中国健康心理学杂志, 2021, 29(4): 509-513. https://www.cnki.com.cn/Article/CJFDTOTAL-JKXL202104008.htm

    FANG M J, XU Y Y, YANG R M, et al. Investigation on resilience level of Wilson disease patients and its influencing factors[J]. China Journal of Health Psychology, 2021, 29(4): 509-513. https://www.cnki.com.cn/Article/CJFDTOTAL-JKXL202104008.htm
    [7]
    庄艳红, 王励. 治疗性沟通对肝豆状核变性患者抑郁及生活质量的提升探讨[J]. 中外医疗, 2021, 40(9): 156-159. https://www.cnki.com.cn/Article/CJFDTOTAL-HZZZ202109065.htm

    ZHUANG Y H, WANG L. Therapeutic communication on the improvement of depression and quality of life in patients with hepatolenticular degeneration[J]. China & Foreign Medical Treatment, 2021, 40(9): 156-159. https://www.cnki.com.cn/Article/CJFDTOTAL-HZZZ202109065.htm
    [8]
    经坤, 蔡永亮. 肝豆状核变性相关实验室检查回顾及思考[J]. 中医药临床杂志, 2016, 28(2): 269-272. https://www.cnki.com.cn/Article/CJFDTOTAL-AHLC201602047.htm

    JING K, CAI Y L. Hepatolenticular degeneration related laboratory examination review and thinking[J]. Clinical Journal of Traditional Chinese Medicine, 2016, 28(2): 269-272. https://www.cnki.com.cn/Article/CJFDTOTAL-AHLC201602047.htm
    [9]
    李爱萍, 周香雪, 蒲小勇, 等. 肝豆状核变性的头部磁共振量化及异常信号与临床特点的关系[J]. 实用医学杂志, 2019, 35(13): 2142-2147. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ201913027.htm

    LI A P, ZHOU X X, PU X Y, et al. Relationship between clinical features and abnormal signals tested by quantitative method of brain magnetic resonance imaging in Wilson disease patients[J]. The Journal of Practical Medicine, 2019, 35(13): 2142-2147. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYZ201913027.htm
    [10]
    宋玉坤, 陈颖茜, 初建平, 等. 神经突起方向离散度和密度成像定量评估肝豆状核变性患者脑核团微结构改变[J]. 中国医学影像技术, 2018, 34(5): 650-655. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXX201805005.htm

    SONG Y K, CHEN Y Q, CHU J P, et al. Quantitative evaluation of microstructural changes of brain nuclei in Wilson' s disease with neurite orientation dispersion and density imaging[J]. Chinese Journal of Medical Imaging Technology, 2018, 34(5): 650-655. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXX201805005.htm
    [11]
    周香雪, 李欣蓓, 初建平, 等. 肝豆状核变性患者锥体外系核团功能活动的静息态功能磁共振研究[J]. 中华神经科杂志, 2016, 49(9): 703-708.

    ZHOU X X, LI X B, CHU J P, et al. Evaluating the functional activity of the subcortical nuclei in Wilson's disease using resting state functional magnetic resonance imaging[J]. hinese Journal of Neurology, 2016, 49(9): 703-708.
    [12]
    王芳, 沈文超, 胡笑楠, 等. 皮质-基底神经节-丘脑-皮质环路与抑郁症状调节的机制探讨[J]. 临床精神医学杂志, 2021, 31(4): 326-329. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS202104025.htm

    WANG F, SHEN W C, HU X N, et al. Discussion on the mechanism of cortical-striatum-thalamus-cortical circuit and symptom regulation of depression[J]. Journal of Clinical Psychiatry, 2021, 31(4): 326-329. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS202104025.htm
    [13]
    KELLEY N J, HUGHES M L. Resting frontal EEG asymmetry and emotion regulation in older adults: The midlife in the United States (MIDUS) study[J]. Psychol Aging, 2019, 34(3): 341-347.
    [14]
    林江南, 曹志坚, 王晓航, 等. 脑梗死后抑郁患者杏仁核及其亚区的功能连接研究[J]. 浙江医学, 2019, 41(12): 1278-1282. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJYE201912015.htm

    LIN J N, CAO Z J, WANG X H, et al. Alteration of brain functional connectivity of amygdala and its sub-regions with other brain regions in patients with post-stroke depression[J]. Zhejiang Medical Journal, 2019, 41(12): 1278-1282. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJYE201912015.htm
    [15]
    王共强, 林康, 马心锋, 等. Wilson病患者认知功能障碍及其危险因素[J]. 中国神经精神疾病杂志, 2019, 45(6): 321-325. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSJJ201906001.htm

    WANG G Q, LIN K, MA X F, et al. Study on cognitive impairment and risk factors in patients with Wilson disease[J]. Chinese Journal of Nervous and Mental Diseases, 2019, 45(6): 321-325. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSJJ201906001.htm
    [16]
    刘念, 王越, 史丹丹, 等. 以神经精神症状为首发的儿童肝豆状核变性特点研究[J]. 河南医学研究, 2020, 29(18): 3280-3282. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYX202018005.htm

    LIU N, WANG Y, SHI D D, et al. A Study on the characteristics of Wilson' s disease in children with neuropsychiatric symptoms[J]. Henan Medical Research, 2020, 29(18): 3280-3282. https://www.cnki.com.cn/Article/CJFDTOTAL-HNYX202018005.htm
    [17]
    吴志英. 中国肝豆状核变性诊治指南2021更新要点解读[J]. 中华神经科杂志, 2021, 54(4): 303-304.

    WU Z Y. Interpretation of updated key points of Chinese guidelines for diagnosis and treatment of Wilson' s disease 2021[J]. Chinese Journal of Neurology, 2021, 54(4): 303-304.
    [18]
    周香雪, 何荣兴, 蒲小勇, 等. 肝豆状核变性携带者的临床特点及治疗策略[J]. 中华医学杂志, 2019, 99(11): 806-811.

    ZHOU X X, HE R X, PU X Y, et al. Clinical characteristics of the Wilson disease carrier[J]. National Medical Journal of China, 2019, 99(11): 806-811.
    [19]
    金平, 王共强, 付晓明, 等. 肝豆状核变性患者认知情绪调节方式的特征及与病变脑区的关系[J]. 中华行为医学与脑科学杂志, 2020, 29(5): 437-441.

    JIN P, WANG G Q, FU X M, et al. Characteristics of cognitive emotion regulation and its relationship with brain lesions in patients with hepatolenticular degeneration[J]. Chinese Journal of Behavioral Medicine and Brain Science, 2020, 29(5): 437-441.
    [20]
    宋婷婷, 周水连, 金艳, 等. 团体心理护理对肝豆状核变性肝硬化患者情绪的影响[J]. 当代护士(中旬刊), 2021, 28(3): 127-129. https://www.cnki.com.cn/Article/CJFDTOTAL-DDHS202103051.htm

    宋婷婷, 周水连, 金艳, 等. Effect of group psychological nursing on emotion of hepatolenticular degeneration patients with cirrhosis[J]. 当代护士(中旬刊), 2021, 28(3): 127-129. https://www.cnki.com.cn/Article/CJFDTOTAL-DDHS202103051.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Article Metrics

    Article views (226) PDF downloads(4) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return