Effects of vertebral osteotomy on spinal-cord function in rabbits

ZHU Zhong-lian; ZHAO Zhi; WANG Zhao-dong; GAO Xu-bin; WANG Xu-yi; GUAN Jian-zhong

doi:10.16766/j.cnki.issn.1674-4152.002630

Volume 20 Issue 9

Sep. 2022

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Article Navigation > Chinese Journal of General Practice > 2022 > 20(9): 1488-1490

ZHU Zhong-lian, ZHAO Zhi, WANG Zhao-dong, GAO Xu-bin, WANG Xu-yi, GUAN Jian-zhong. Effects of vertebral osteotomy on spinal-cord function in rabbits[J]. Chinese Journal of General Practice, 2022, 20(9): 1488-1490. doi: 10.16766/j.cnki.issn.1674-4152.002630

Citation:

ZHU Zhong-lian, ZHAO Zhi, WANG Zhao-dong, GAO Xu-bin, WANG Xu-yi, GUAN Jian-zhong. Effects of vertebral osteotomy on spinal-cord function in rabbits[J]. Chinese Journal of General Practice, 2022, 20(9): 1488-1490. doi: 10.16766/j.cnki.issn.1674-4152.002630

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Effects of vertebral osteotomy on spinal-cord function in rabbits

doi: 10.16766/j.cnki.issn.1674-4152.002630

ZHU Zhong-lian^{1, 2}
, ZHAO Zhi^{1, 2}
, WANG Zhao-dong^{1, 2}
, GAO Xu-bin^{1, 2}
, WANG Xu-yi^{1, 2}
, GUAN Jian-zhong^{1, 2
,
,}

1.
Department of Orthopedics, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

SK2018A1077

BYKY2019039ZD

BYKY1776

Received Date: 2022-02-09
Available Online: 2022-11-29

Abstract

Abstract

Objective To explore the effect of vertebral osteotomy on the function of the spinal cord and to provide a theoretical basis for the clinical application of vertebral osteotomy. Methods By random-number table method, 40 rabbits were randomly divided into a control group, a low osteotomy group (compression 25% after osteotomy), a middle osteotomy group (compression 50% after osteotomy), and a high osteotomy group (compression 100% after osteotomy), with 10 animals each. They were given corresponding surgical treatment. Dural shrinkage, motor function (Reuter score), spinal-cord blood flow, and other indicators were determined. Results The dural sac transverse diameter and spinal cord of the middle and high osteotomy groups were (5.74±0.29) mm, (14.46±0.77)° and (7.65±0.36) mm, (85.62±2.95)°, which were higher than those of the low osteotomy[(4.85±0.32) mm, 0°] and control group [(4.39±0.11) mm, 0°], all P < 0.05. The blood flow of the middle and high osteotomy groups were (27.66±0.85) μL/100 μm³ and (10.53±0.24) μL/100 μm³, which were lower than those of the low osteotomy [(34.28±0.94) μL/100 μm³] and control group [(33.81±1.06) μL/100 μm³], all P < 0.05. The Reuter score of the low, middle, and high osteotomy groups [(2.38±0.34) points, (7.25±0.42) points, (9.56±0.73) points] were significantly higher than those of the control group[(1.39±0.25) points, all P < 0.05]. Conclusion Vertebral osteotomy has a good clinical effect. Shorter spine shortening has little effect on spinal-cord function. In clinical practice, attention should be paid to the critical value of safe osteotomy.
- Spinal shortening,
- Spinal cord function,
- Spinal-cord blood flow

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References(18)

References

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Effects of vertebral osteotomy on spinal-cord function in rabbits

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