Volume 20 Issue 9
Sep.  2022
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XIE Shuo, LI Jia-xin, LIU Xin-min, JIAO Hong-mei. Characteristics and predictive factors of chronic critical illness[J]. Chinese Journal of General Practice, 2022, 20(9): 1555-1559. doi: 10.16766/j.cnki.issn.1674-4152.002648
Citation: XIE Shuo, LI Jia-xin, LIU Xin-min, JIAO Hong-mei. Characteristics and predictive factors of chronic critical illness[J]. Chinese Journal of General Practice, 2022, 20(9): 1555-1559. doi: 10.16766/j.cnki.issn.1674-4152.002648

Characteristics and predictive factors of chronic critical illness

doi: 10.16766/j.cnki.issn.1674-4152.002648
  • Received Date: 2022-04-29
    Available Online: 2022-11-29
  • With the development of modern evidence-based medicine and the improvement in intensive-care technology, some critically ill patients who survive from the initial acute critical state after treatment are bound to have persistent organ dysfunctions. Accordingly, they need to rely on intensive care and organ support for a long time. These patients experience persistent organ damage and even chronically persistent inflammation, immunosuppression, and catabolic syndrome that progress to chronic critical illness. Chronic critical illness is prone to physical, psychological, and cognitive-related dysfunction, with high mortality and morbidity. The health of these patients is not protected, but the time to death is prolonged by technology. They are often hospitalised for longer periods of time, suffer permanent disability and severe distress, reduce their quality of life, and affect their entire family. At present, the definition of chronic critical illness has not been unified, but the standard is based on a certain length of hospitalisation plus severe organ damage. Epidemiological surveys in many countries have shown that the incidence of chronic critical illness increases yearly. With the aging of the population, it has become an increasingly serious global problem. Many studies have been performed to explore the pathogenesis and risk factors of chronic critical illness, predict the development of chronic critical illness, and reduce the impact of chronic critical illness on patients and their families. This review aims to summarise the progress of research on the definition, epidemiology, pathogenesis, and predictive factors of chronic critical illness to improve clinicians ' understanding and ability to prevent chronic critical illness. We provide a reference for the diagnosis and treatment of chronic critical illness, as well as enrich the knowledge of diagnosis and treatment strategies to further improve the quality of life of chronic critical-illness patients.

     

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