Volume 20 Issue 10
Oct.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(10): 1691-1694
WANG Xian, PAN Yan, BA Ming-yu, WAN Hong, FU Yu, YAN Shu-xun. Study on the relationship between dietary factors and mean amplitude of glycemic excursions in patients with diabetes mellitus type 2[J]. Chinese Journal of General Practice, 2022, 20(10): 1691-1694. doi: 10.16766/j.cnki.issn.1674-4152.002681
Citation: WANG Xian, PAN Yan, BA Ming-yu, WAN Hong, FU Yu, YAN Shu-xun. Study on the relationship between dietary factors and mean amplitude of glycemic excursions in patients with diabetes mellitus type 2[J]. Chinese Journal of General Practice, 2022, 20(10): 1691-1694. doi: 10.16766/j.cnki.issn.1674-4152.002681
shu

Study on the relationship between dietary factors and mean amplitude of glycemic excursions in patients with diabetes mellitus type 2

doi: 10.16766/j.cnki.issn.1674-4152.002681

  • Department of Endocrinology, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan 450001, China

Funds:

 2100601-CZ01-01

 2022JDZX021

  • Received Date: 2021-01-12
    Available Online: 2022-11-30
    Abstract
  •   Objective  To observe the relationship between dietary factors and mean amplitude of glycemic excursions in diabetes mellitus type 2 (T2DM) patients with a dynamic blood glucose monitoring system.  Methods  A total of 346 patients with T2DM aged from 18 to 60 who were hospitalized in the Department of Endocrinology, the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2016 to December 2017 were selected as the study subjects. They were monitored continuously for 72 hours and their amplitude of glycemic excursions were analyzed. The average daily intake of various foods was obtained by 24 hours dietary review method and 3 days condiment estimation method, and the adjusted dietary balance index-07 (DBI-07) was used to calculate the intake score of various foods. The subjects were divided into three groups according to the mean amplitude of glycemic excursions (MAGE) level, and the differences in food intake scores of each group were compared. Multivariate linear regression was used to assess the influence of dietary factors on amplitude of glycemic excursions.  Results  With the increase of the amplitude of glycemic excursions, the level of prealbumin and skeletal muscle mass of the limbs decreased (F=47.124, 17.354, trend P < 0.001, < 0.001). Participants consumed 250 mL of dairy products per day had a 14.0% decrease in the mean amplitude of glycemic excursions compared to those who did not consume enough dairy products (OR=0.860, 95% CI: 0.818-0.895). Participants with vegetable intake greater than 150 g/d had a 9.9% decrease in the mean amplitude of glycemic excursions compared with less vegetable intake (OR=0.901, 95% CI: 0.845-0.962).  Conclusion  Insufficient intake of dairy products and vegetable is associated with increased blood glucose fluctuation, and the prevention of protein malnutrition should be emphasized in the medical nutritional treatment in type 2 diabetes.

     

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    • References(18)
  • [1]
    LENG Y L, ZHOU X J, XIE Z Y, et al. Efficacy and safety of Chinese herbal medicine on blood glucose fluctuations in patients with type 2 diabetes mellitus: A protocol of systematic review and meta-analysis[J]. Medicine (Baltimore), 2020, 99(34): e21904. DOI: 10.1097/MD.0000000000021904.
    [2]
    WANG J S, LEE I T, LEE W J, et al. Glycemic excursions are positively associated with HbA1c reduction from baseline after treatment with acarbose in patients with type 2 diabetes on metformin monotherapy[J]. J Diabetes, 2017, 9(3): 248-255. doi: 10.1111/1753-0407.12406
    [3]
    洪新宇, 杨正丽, 马运芹, 等. 波动性高糖对内皮细胞自噬基因表达的影响[J]. 上海预防医学, 2020, 32(3): 248-252. doi: 10.19428/j.cnki.sjpm.2020.19794

    HONG X Y, YANG Z L, MA Y Q, et al. Effects of fluctuant hyperglycemia on autophagy of endothelial cells[J]. Shanghai Journal of Preventive Medicine, 2020, 32(3): 248-252. doi: 10.19428/j.cnki.sjpm.2020.19794
    [4]
    喻莉. 不同膳食营养干预对妊娠期糖尿病患者血糖波动、BMI指数及妊娠结局的影响[J]. 内蒙古医学杂志, 2018, 50(6): 684-685. https://www.cnki.com.cn/Article/CJFDTOTAL-NMYZ201806024.htm

    YU L. Effects of different dietary nutritional interventions on blood glucose fluctuation, BMI index and pregnancy outcomes in patients with gestational diabetes mellitus[J]. Inner Mongolia Medical Journal, 2018, 50(6): 684-685. https://www.cnki.com.cn/Article/CJFDTOTAL-NMYZ201806024.htm
    [5]
    张红茹, 郭瑛. 低血糖生成指数膳食干预在妊娠糖尿病孕妇中的应用效果[J]. 临床医学研究与实践, 2020, 5(11): 78-80. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS202011035.htm

    ZHANG H R, GUO Y. Application effect of low-glycemic index dietary in pregnant women with gestational diabetes mellitus[J]. Clinical Research and Practice, 2020, 5(11): 78-80. https://www.cnki.com.cn/Article/CJFDTOTAL-YLYS202011035.htm
    [6]
    ALBERTI K G, ZIMMET P Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation[J]. Diabet Med, 1998, 15(7): 539-553. doi: 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S
    [7]
    董玉婷, 鲍勇, 彭慧, 等. 上海市嘉定区中小学生膳食中营养素摄入情况分析及政策建议[J]. 中华全科医学, 2020, 18(1): 134-138. doi: 10.16766/j.cnki.issn.1674-4152.001187

    DONG Y T, BAO Y, PENG H, et al. Analysis of dietary nutrient intake and policy recommendations for primary and middle school students in Jiading District of Shanghai[J]. Chinese Journal of General Practice, 2020, 18(1): 134-138. doi: 10.16766/j.cnki.issn.1674-4152.001187
    [8]
    凡亚云, 何定留, 刘中春, 等. 应用调整的膳食平衡指数评价中老年肌少症患者的膳食质量[J]. 现代预防医学, 2020, 47(13): 2342-2345, 2367. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202013009.htm

    FAN Y Y, HE D L, LIU Z C, et al. Evaluation on the dietary quality of middle-aged and old patients with sarcopenia by adjusted dietary balance index[J]. Modern Preventive Medicine, 2020, 47(13): 2342-2345, 2367. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202013009.htm
    [9]
    金百翰, 宋敬云, 谢俊豪, 等. 血糖波动与氧化应激及细胞因子关系的研究进展[J]. 解放军医学杂志, 2019, 44(12): 1056-1060. doi: 10.11855/j.issn.0577-7402.2019.12.12

    JIN B H, SONG J Y, XIE J H, et al. Research progress on the relationship between glycemic variability and oxidative stress or cytokines[J]. Medical Journal of Chinese People ' s Liberation Army, 2019, 44(12): 1056-1060. doi: 10.11855/j.issn.0577-7402.2019.12.12
    [10]
    黄双丽, 秦莲花, 钟洁平, 等. 血糖波动与进展性缺血性卒中患者疾病发展的研究进展[J]. 实用医院临床杂志, 2021, 18(2): 188-190. doi: 10.3969/j.issn.1672-6170.2021.02.055

    HUANG S L, QIN L H, ZHONG J P, et al. Research progress in the relationship between glycemic variability and development of progressive ischemic stroke[J]. Practical Journal of Clinical Medicine, 2021, 18(2): 188-190. doi: 10.3969/j.issn.1672-6170.2021.02.055
    [11]
    王娴, 潘研, 巴明玉, 等. 应用膳食平衡指数分析郑州市18~45岁青年人群膳食因素与2型糖尿病的关系研究[J]. 现代预防医学, 2019, 46(19): 3490-3495. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201919010.htm

    WANG X, PAN Y, BA M Y, et al. Association between dietary balance index and type 2 diabetes among people aged 18 - 45 years, Zhengzhou[J]. Modern Preventive Medicine, 2019, 46(19): 3490-3495. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF201919010.htm
    [12]
    张幽幽, 陶海英, 金都, 等. 应用722实时动态胰岛素泵系统监测血糖变化的临床分析[J]. 中华全科医学, 2018, 16(12): 2024-2027. doi: 10.16766/j.cnki.issn.1674-4152.000552

    ZHANG Y Y, TAO H Y, JIN D, et al. Clinical analysis of blood glucose monitoring by real-time insulin pump system[J]. Chinese Journal of General Practice, 2018, 16(12): 2024-2027. doi: 10.16766/j.cnki.issn.1674-4152.000552
    [13]
    郗光霞, 安平, 梁登耀, 等. 糖化血红蛋白水平和血糖波动与氧化应激关系的研究[J]. 中国糖尿病杂志, 2021, 29(2): 99-103. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGTL202102005.htm

    XI G X, AN P, LIANG D Y, et al. Relationship between HbAc levels and blood glucose fluctuations and oxidative stress[J]. Chinese Journal of Diabetes, 2021, 29(2): 99-103. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGTL202102005.htm
    [14]
    周常春, 敬然, 谢晓敏. 碳水化合物与蛋白质构成比对2型糖尿病患者餐后血糖的影响[J]. 宁夏医学杂志, 2019, 41(9): 850-852. https://www.cnki.com.cn/Article/CJFDTOTAL-NXYX201909039.htm

    ZHOU C C, JING R, XIE X M. Effect of carbohydrate to protein composition ratio on postprandial blood glucose in type 2 diabetic patients[J]. Ningxia Medical Journal, 2019, 41(9): 850-852. https://www.cnki.com.cn/Article/CJFDTOTAL-NXYX201909039.htm
    [15]
    FUJIWARA Y, EGUCHI S, MURAYAMA H, et al. Relationship between diet/exercise and pharmacotherapy to enhance the GLP-1 levels in type 2 diabetes[J]. Endocrinol Diabetes Metab, 2019, 2(3): e00068. DOI: 10.1002/edm2.68.
    [16]
    ZHANG J, OH E, MERZ K E, et al. DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle[J]. Diabetologia, 2019, 62(5): 845-859.
    [17]
    王艳峰, 杨锡洪, 曹峻菡, 等. 膳食纤维调节2型糖尿病血糖作用研究进展[J]. 食品与机械, 2020, 36(10): 6-11, 17. https://www.cnki.com.cn/Article/CJFDTOTAL-SPJX202010002.htm

    WANG Y F, YANG X H, CAO J H, et al. Research progress on the mechanism of dietary fiber in regulating blood sugar of type 2 diabetes[J]. Food and Machinery, 2020, 36(10): 6-11, 17. https://www.cnki.com.cn/Article/CJFDTOTAL-SPJX202010002.htm
    [18]
    戴春. 麦麸膳食纤维对控制中老年糖尿病患者血糖效果研究[J]. 中国食物与营养, 2020, 26(3): 57-60. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGWY202003014.htm

    DAI C. Effect of wheat bran dietary fiber on blood sugar control in middle-aged and elderly diabetic patients[J]. Food and Nutrition in China, 2020, 26(3): 57-60. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGWY202003014.htm
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