Volume 20 Issue 10
Oct.  2022
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Article Navigation >  Chinese Journal of General Practice  > 2022  >  20(10): 1733-1736
XIAO Ling-na, ZENG An-ning, LUO Yong, MA Bing-lian, LYU Ting-yong. Study on the clinical effect of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with atrial fibrillation[J]. Chinese Journal of General Practice, 2022, 20(10): 1733-1736. doi: 10.16766/j.cnki.issn.1674-4152.002691
Citation: XIAO Ling-na, ZENG An-ning, LUO Yong, MA Bing-lian, LYU Ting-yong. Study on the clinical effect of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with atrial fibrillation[J]. Chinese Journal of General Practice, 2022, 20(10): 1733-1736. doi: 10.16766/j.cnki.issn.1674-4152.002691
shu

Study on the clinical effect of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with atrial fibrillation

doi: 10.16766/j.cnki.issn.1674-4152.002691
  • 1.

    Department of Medical Imaging, People' s Hospital of Qiannan Buyi and Miao Autonomous Prefecture, Duyun, Guizhou 558000, China

Funds:

 201712

 gzwjkj2020-1-069

  • Received Date: 2022-05-19
    Available Online: 2022-11-30
    Abstract
  •   Objective  To observe the clinical effect of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with atrial fibrillation (AF).  Methods  Three hundred and fifty AF patients admitted to the People' s Hospital of Buyi and Miao Autonomous Prefecture of Qiannan Prefecture from April 2019 to April 2022 were selected as the study objects. All patients underwent transesophageal echocardiography (TEE), real-time three-dimensional transthoracic echocardiography (RT-3DTTE) and dual phase enhanced CT scanning. Taking the results of TEE as the gold standard, the diagnostic efficacy of RT-3DTTE and dual phase enhanced CT scanning were evaluated. The differences of left atrial structural indexes between patients with auricular thrombosis and patients without auricular thrombosis were compared.  Results  The detection rate of left atrial appendage thrombosis in patients with AF was 12.29%(43/350) using TEE examination. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with AF (97.67%, 98.70%, 98.57%, 91.30%, 99.67%) were significantly higher than those of RT-3DTTE (79.08%, 87.30%, 86.28%, 46.57% and 96.75%; χ2=7.242, P=0.007; χ2=30.634, P < 0.001; χ2=37.745, P < 0.001; χ2=24.464, P < 0.001; χ2=5.682, P=0.017). The area under ROC curve (0.955) of dual phase enhanced CT scanning in the diagnosis of left atrial appendage thrombosis in patients with AF was higher than that of RT-3DTTE (0.717). The detection values of left atrial anterior posterior diameter, left atrial transverse diameter and left atrial upper and lower diameter in patients with left atrial appendage thrombosis diagnosed by dual phase enhanced CT scanning were significantly higher than those in patients without left atrial appendage thrombosis (all P < 0.05).  Conclusion  The diagnostic ability of dual phase enhanced CT scanning for left atrial appendage thrombosis in patients with AF is comparable to TEE, but the operation is simpler, non-invasive and has high clinical value.

     

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