Volume 21 Issue 1
Jan.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(1): 33-36
LIU Yan-yi, ZHU Hai-juan, DONG Wen-peng, ZHU Bang-qiang, LI Xiang-yun, LI Feng. Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation[J]. Chinese Journal of General Practice, 2023, 21(1): 33-36. doi: 10.16766/j.cnki.issn.1674-4152.002805
Citation: LIU Yan-yi, ZHU Hai-juan, DONG Wen-peng, ZHU Bang-qiang, LI Xiang-yun, LI Feng. Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation[J]. Chinese Journal of General Practice, 2023, 21(1): 33-36. doi: 10.16766/j.cnki.issn.1674-4152.002805
shu

Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation

doi: 10.16766/j.cnki.issn.1674-4152.002805
  • 1.

    Department of Cardiac Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 82100315

 LCYJ2021YB016

  • Received Date: 2022-08-02
    Available Online: 2023-04-07
    Abstract
  •   Objective  This study aimed to investigate the clinical values of preoperative autologous blood donation (PABD) in selective cardiac surgeries under extracorporeal circulation (SCSUEC) and to discuss the safety and feasibility of PABD.  Methods  A total of 81 patients who consecutively received SCSUEC combined with PABD in the First Affiliated Hospital of Anhui Medical University from January 2015 to July 2021 were enrolled as the experimental group. Another 81 patients from the same hospital were matched by gender and baseline haemoglobin level (±1.5 g/dL), and they received SCSUEC at a ratio of 1 :1, which were determined as the case control. Comprehensive comparisons in the transfusion amount of allogenic RBC and plasma, the cost of transfusion, the postoperative recovery parameters and postoperative complications were conducted between the two groups.  Results  Compared with the case control, participants in the experimental group have significantly less allogenic RBC transfusion [2.00 (0.00, 4.00) U vs. 5.50 (4.00, 8.00) U], less allogenic plasma transfusion [600.00 (400.00, 800.00) mL vs. 800.00 (600.00, 1 325.00) mL], less first 24 h drainage [445.00 (310.00, 567.50) mL vs. 575.00 (433.50, 860.00) mL], shorter mechanical ventilation time [16.00 (8.00, 18.00) h vs. 18.00 (11.00, 26.00) h] and shorter ICU stay [43.00 (36.00, 65.00) h vs. 58.00 (41.00, 94.00) h] were significantly decreased (all P < 0.05). Furthermore, less incidence of acute renal failure, haemoglobinuria and prolonged mechanical ventilation were observed in the experimental group (all P < 0.05). The difference in costs related to blood transfusion was statistically significant between two groups (P < 0.05).  Conclusion  PABD can reduce the demand for allogenic RBC and plasma transfusion in SCSUEC. It can also be used to avoid postoperative complications and promote postoperative recovery.

     

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    • References(15)
  • [1]
    谢屹红, 戴备军, 沈社良. 血栓弹力图指导体外循环心脏手术围术期输血对患者出血量、输血量和临床结局的影响[J]. 中华全科医学, 2019, 17(5): 756-760. doi: 10.16766/j.cnki.issn.1674-4152.000784

    XIE Y H, DAI B J, SHEN S L. Comparison of thromboelastography and standard coagulation tests guided perioperative period transfusion in patients undergoing cardiac surgery with cardiopulmonary bypass[J]. Chinese Journal of General Practice, 2019, 17(5): 756-760. doi: 10.16766/j.cnki.issn.1674-4152.000784
    [2]
    黄慧瑛, 黄建云, 魏亚明, 等. 贮存式自体血输注在普外科择期手术中的临床应用研究[J]. 中国实验血液学杂志, 2020, 28(3): 967-971. https://www.cnki.com.cn/Article/CJFDTOTAL-XYSY202003046.htm

    HUANG H Y, HUANG J Y, WEI Y M, et al. Clinical application of preoperative autologous blood donation in selective general surgery[J]. Journal of Experimental Hematology, 2020, 28(3): 967-971. https://www.cnki.com.cn/Article/CJFDTOTAL-XYSY202003046.htm
    [3]
    FRANK S M, SIKORSKI R A, KONIG G, et al. Clinical utility of autologous salvaged blood: a review[J]. J Gastrointest Surg, 2020, 24(2): 464-472. doi: 10.1007/s11605-019-04374-y
    [4]
    李倩, 吕红, 刘岳, 等. 心血管手术围术期抗纤溶治疗的有效性及安全性[J]. 中国临床药理学与治疗学, 2021, 26(7): 830-835. https://www.cnki.com.cn/Article/CJFDTOTAL-YLZL202107016.htm

    LI Q, LYU H, LIU Y, et al. Efficacy and safety of antifibrinolytic therapy in the perioperative cardio-vascular surgery[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2021, 26(7): 830-835. https://www.cnki.com.cn/Article/CJFDTOTAL-YLZL202107016.htm
    [5]
    郑伟健, 方卫平, 汪欢, 等. 回收式自体输血在老年患者不停跳冠脉搭桥术中的应用[J]. 安徽医科大学学报, 2018, 53(10): 1602-1605. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE201810024.htm

    ZHENG W J, FANG W P, WANG H, et al. Application of intraoperative blood salvage in elderly patients with off-pump coronary artery bypass grafting[J]. Acta Universitatis Medicinalis Anhui, 2018, 53(10): 1602-1605. https://www.cnki.com.cn/Article/CJFDTOTAL-YIKE201810024.htm
    [6]
    丁洁岚, 冯娟, 陈皆锋, 等. 产科大量输血方案的临床研究进展[J]. 中华全科医学, 2022, 20(3): 468-472. doi: 10.16766/j.cnki.issn.1674-4152.002380

    DING J L, FENG J, CHEN J F, et al. Clinical research progress related to massive blood transfusion in obstetrics[J]. Chinese Journal of General Practice, 2022, 20(3): 468-472. doi: 10.16766/j.cnki.issn.1674-4152.002380
    [7]
    VLOT E A, VERWIJMEREN L, VAN DE GARDE E, et al. Intra-operative red blood cell transfusion and mortality after cardiac surgery[J]. BMC Anesthesiol, 2019, 19(1): 65.
    [8]
    MING Y, LIU J, ZHANG F, et al. Transfusion of red blood cells, fresh frozen plasma, or platelets is associated with mortality and infection after cardiac surgery in a dose-dependent manner[J]. Anesth Analg, 2020, 130(2): 488-497.
    [9]
    SULTAN I, BIANCO V, BROWN J A, et al. Long-term impact of perioperative red blood cell transfusion on patients undergoing cardiac surgery[J]. Ann Thorac Surg, 2021, 112(2): 546-554.
    [10]
    YOU G X, LI B T, WANG Z, et al. Effects of different plasma expanders on rats subjected to severe acute normovolemic hemodilution[J]. Mil Med Res, 2020, 7(1): 55.
    [11]
    ADAM E H, FUNKE M, ZACHAROWSKI K, et al. Impact of intraoperative cell salvage on blood coagulation factor concentrations in patients undergoing cardiac surgery[J]. Anesth Analg, 2020, 130(5): 1389-1395.
    [12]
    龚由伟, 薛颖泓, 唐涌连, 等. 预存式自体输血对原发性肝癌患者围术期免疫功能的影响[J]. 广西医科大学学报, 2020, 37(9): 1648-1652. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD202009014.htm

    GONG Y W, XUE Y H, TANG Y L, et al. Effect of preoperative autologous blood donation on perioperative immune function in patients with primary liver cancer[J]. Journal of Guangxi Medical University, 2020, 37(9): 1648-1652. https://www.cnki.com.cn/Article/CJFDTOTAL-GXYD202009014.htm
    [13]
    GRETCHEN C, BAYIR H, KOCHANEK P M, et al. Association between hyperoxemia and increased cell-free plasma hemoglobin during cardiopulmonary bypass in infants and children[J]. Pediatr Crit Care Med, 2022, 23(2): e111-e119.
    [14]
    KINDZELSKI B A, CORCORAN P, SIEGENTHALER M P, et al. Postoperative acute kidney injury following intraoperative blood product transfusions during cardiac surgery[J]. Perfusion, 2018, 33(1): 62-70.
    [15]
    RASMUSSEN S R, KANDLER K, NIELSEN R V, et al. Association between transfusion of blood products and acute kidney injury following cardiac surgery[J].Acta Anaesthesiol Scand, 2020, 64 (10):1397-1404.
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