Volume 21 Issue 1
Jan.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(1): 33-36
LIU Yan-yi, ZHU Hai-juan, DONG Wen-peng, ZHU Bang-qiang, LI Xiang-yun, LI Feng. Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation[J]. Chinese Journal of General Practice, 2023, 21(1): 33-36. doi: 10.16766/j.cnki.issn.1674-4152.002805
Citation: LIU Yan-yi, ZHU Hai-juan, DONG Wen-peng, ZHU Bang-qiang, LI Xiang-yun, LI Feng. Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation[J]. Chinese Journal of General Practice, 2023, 21(1): 33-36. doi: 10.16766/j.cnki.issn.1674-4152.002805
shu

Clinical application of preoperative autologous blood donation in selective cardiac surgery under extracorporeal circulation

doi: 10.16766/j.cnki.issn.1674-4152.002805
  • 1.

    Department of Cardiac Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, China

Funds:

 82100315

 LCYJ2021YB016

  • Received Date: 2022-08-02
    Available Online: 2023-04-07
    Abstract
  •   Objective  This study aimed to investigate the clinical values of preoperative autologous blood donation (PABD) in selective cardiac surgeries under extracorporeal circulation (SCSUEC) and to discuss the safety and feasibility of PABD.  Methods  A total of 81 patients who consecutively received SCSUEC combined with PABD in the First Affiliated Hospital of Anhui Medical University from January 2015 to July 2021 were enrolled as the experimental group. Another 81 patients from the same hospital were matched by gender and baseline haemoglobin level (±1.5 g/dL), and they received SCSUEC at a ratio of 1 :1, which were determined as the case control. Comprehensive comparisons in the transfusion amount of allogenic RBC and plasma, the cost of transfusion, the postoperative recovery parameters and postoperative complications were conducted between the two groups.  Results  Compared with the case control, participants in the experimental group have significantly less allogenic RBC transfusion [2.00 (0.00, 4.00) U vs. 5.50 (4.00, 8.00) U], less allogenic plasma transfusion [600.00 (400.00, 800.00) mL vs. 800.00 (600.00, 1 325.00) mL], less first 24 h drainage [445.00 (310.00, 567.50) mL vs. 575.00 (433.50, 860.00) mL], shorter mechanical ventilation time [16.00 (8.00, 18.00) h vs. 18.00 (11.00, 26.00) h] and shorter ICU stay [43.00 (36.00, 65.00) h vs. 58.00 (41.00, 94.00) h] were significantly decreased (all P < 0.05). Furthermore, less incidence of acute renal failure, haemoglobinuria and prolonged mechanical ventilation were observed in the experimental group (all P < 0.05). The difference in costs related to blood transfusion was statistically significant between two groups (P < 0.05).  Conclusion  PABD can reduce the demand for allogenic RBC and plasma transfusion in SCSUEC. It can also be used to avoid postoperative complications and promote postoperative recovery.

     

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