Volume 21 Issue 1
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QIAN Xiong, ZHANG Yin-min, CHEN Kai. Clinical effect of Yunpi Buxue Decoction in the treatment of children with iron deficiency anaemia[J]. Chinese Journal of General Practice, 2023, 21(1): 88-91. doi: 10.16766/j.cnki.issn.1674-4152.002819
Citation: QIAN Xiong, ZHANG Yin-min, CHEN Kai. Clinical effect of Yunpi Buxue Decoction in the treatment of children with iron deficiency anaemia[J]. Chinese Journal of General Practice, 2023, 21(1): 88-91. doi: 10.16766/j.cnki.issn.1674-4152.002819
shu

Clinical effect of Yunpi Buxue Decoction in the treatment of children with iron deficiency anaemia

doi: 10.16766/j.cnki.issn.1674-4152.002819

  • Department of Pediatrics, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, Zhejiang 314001, China

Funds:

 2020ZB254

  • Received Date: 2022-01-16
    Available Online: 2023-04-07
    Abstract
  •   Objective  This study aims to investigate the short-term and long-term curative effect of Yunpi Buxue Decoction in the treatment of children with iron deficiency anaemia and its influence on iron metabolism indexes to provide reference for their clinical treatment.  Methods  Eighty children with nutritional iron deficiency anaemia of spleen-stomach weakness syndrome who were admitted to Jiaxing Hospital of Traditional Chinese Medicine from September 2019 to June 2020 were selected and divided into the control group (n=40) and observation group (n=40) using the random number table method. The control group was treated with vitamin C combined with iron dextran oral liquid, and the observation group was treated with Yunpi Buxue Decoction based on the control group. The short-term and long-term efficacy, adverse reactions, iron metabolism indexes and laboratory index levels were compared between the 2 groups of children.  Results  The total clinical effective rate of the observation group (92.50%) was apparently higher in comparison with that of the control group (75.00%, χ2=4.501, P < 0.05). After treatment, the mean corpuscular haemoglobin concentration, mean corpuscular volume, haemoglobin, serum iron and transferrin saturation in the observation group [(328.45±32.84) g/L, (85.74±9.20) fL, (130.88±15.66) g/L, (16.65±3.12) μmol/L, and (35.74±6.20) %] were apparently higher compared with those in the control group [(304.74±30.22) g/L, (75.33±8.82) fL, (118.30±17.26) g/L, (13.84±3.05) μmol/L, and (30.55±6.84) %], all P < 0.05. Six months after treatment, the recurrence rate of the observation group (7.50%) was significantly lower in comparison with that of the control group (27.50%; χ2=5.541, P < 0.05). The incidence of adverse reactions in the observation group (17.50%) was not statistically significant compared with that in the control group (12.50%; χ2=0.392, P>0.05).  Conclusion  Yunpi Buxue Decoction combined with vitamin C and iron dextran oral liquid has a significant short-term and long-term curative effect on children with iron deficiency anaemia, which can effectively regulate the body' s blood cells and iron metabolism, and it has a better safety.

     

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