Volume 21 Issue 5
May  2023
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HU Ningning, CHEN Shufang, ZHU Ningning, ZHANG Meng, ZHU Xunbing. Negative pressure closed drainage combined with oxygen transfusion irrigation for infectious wounds after orthopedic surgery[J]. Chinese Journal of General Practice, 2023, 21(5): 779-783. doi: 10.16766/j.cnki.issn.1674-4152.002982
Citation: HU Ningning, CHEN Shufang, ZHU Ningning, ZHANG Meng, ZHU Xunbing. Negative pressure closed drainage combined with oxygen transfusion irrigation for infectious wounds after orthopedic surgery[J]. Chinese Journal of General Practice, 2023, 21(5): 779-783. doi: 10.16766/j.cnki.issn.1674-4152.002982

Negative pressure closed drainage combined with oxygen transfusion irrigation for infectious wounds after orthopedic surgery

doi: 10.16766/j.cnki.issn.1674-4152.002982
Funds:

 KJ2018A0243

 Byycx21019

  • Received Date: 2022-11-12
  •   Objective  To explore the clinical effect of negative pressure closed drainage and oxygen infusion irrigation on infectious wounds after orthopedic surgery, and to provide reference for the study of infectious wounds after orthopedics and related surgery.  Methods  A total of 28 patients with infectious wounds after orthopedic surgery were selected from the Second Affiliated Hospital of Bengbu Medical College from October 2020 to June 2022. They were divided into experimental and control groups according to the random number table method, with 14 patients in each group. The control group received negative pressure closure drainage combined with saline irrigation treatment, while the experimental group received combined oxygen delivery irrigation treatment based on the control group. The two groups were measured and calculated using a sterile wound measuring scale before and 5 to 10 days after surgery, including the wound granulation tissue coverage rate, wound volume reduction rate, wound healing rate, healing time, and bacterial clearance rate. After that, depending on the condition of the wound, a second stage operation or refilling (replacing) the dressing was decided to continue sealing and drainage until it healed.  Results  Intervention after 5-10 d, the granulation tissue coverage rate, volume reduction rate and bacterial clearance rate of the experimental group [(93.03±4.05)%, (42.92±9.20)%, (95.93±4.19)%] were higher than those of the control group [(74.73±5.08)%, (35.18±9.46)%, (87.20±2.35)%]. The differences were statistically significant (t=-10.535, -2.193, -6.796; all P < 0.05); The healing rate of the experimental group was 85.71% (12/14), which was higher than 78.57%(11/14) of the control group, and the difference was not statistically significant (P=0.999). The wound healing time of the experimental group [(29.43±8.54) d] was lower than that of the control group [(32.43±9.04) d], and the difference was not statistically significant (t=0.903, P=0.375).  Conclusion  Compared with negative pressure closed drainage alone, negative pressure closed drainage combined with oxygen transfusion irrigation can promote granulation tissue growth and reduce wound volume, which is worthy of clinical application.

     

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