Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1466-1469
WANG Hang, XU Qixia, LI Xiaoqing, WANG Yueyue. Analysis of long-term prognostic factors in patients with acute pulmonary embolism[J]. Chinese Journal of General Practice, 2023, 21(9): 1466-1469. doi: 10.16766/j.cnki.issn.1674-4152.003147
Citation: WANG Hang, XU Qixia, LI Xiaoqing, WANG Yueyue. Analysis of long-term prognostic factors in patients with acute pulmonary embolism[J]. Chinese Journal of General Practice, 2023, 21(9): 1466-1469. doi: 10.16766/j.cnki.issn.1674-4152.003147
shu

Analysis of long-term prognostic factors in patients with acute pulmonary embolism

doi: 10.16766/j.cnki.issn.1674-4152.003147
  • 1.

    Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 2011BAI11B17

 2016YFC0905600

  • Received Date: 2023-01-04
    Available Online: 2023-10-19
    Abstract
  •   Objective  To analyze the clinical data and laboratory tests of patients with acute pulmonary embolism (APE) in different conditions, explore the influencing factors of adverse events in patients with APE, and carry out reasonable treatment to improve the prognosis.  Methods  A single center of the First Affiliated Hospital of Bengbu Medical College enrolled 202 patients with APE in the national "Twelfth Five-Year Plan" and "Thirteenth Five-Year Plan" registration studies from May 2012 to June 2019, of which 191 patients completed at least 6-month follow-up, and 146 patients completed 3-year follow-up. The follow-up outcome was all-cause mortality. Univariate and multivariate regression were used to analyze the impact of clinical data and laboratory indicators on the long-term prognosis of patients.  Results  A total of 191 patients were followed up at 6 months after diagnosis: 164 cases survived and 27 died. Multivariate COX regression showed that underlying disease of malignancy or chronic cardiopulmonary disease had a significant effect on APE 6-months prognosis (short-term prognosis, P < 0.05). Totally 146 patients completed the 36-month follow-up, 111 survived and 35 died. Multivariate COX regression showed that the combination of malignant tumors, chronic cardiopulmonary diseases, and low serum albumin levels had a significant impact on the 36-month prognosis of patients. The independent risk factors for the long-term prognosis of APE included combination of malignant tumors, chronic cardiopulmonary diseases, and low serum albumin levels.  Conclusion  The combination of malignant tumors, chronic cardiopulmonary diseases, and low serum albumin levels are independent factors affecting the long-term prognosis of pulmonary embolism. Combination of malignant tumors and chronic cardiopulmonary diseases, both long-term and short-term prognosis are poor. Low serum albumin level is an adverse factor for long-term prognosis in acute pulmonary embolism.

     

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