Volume 21 Issue 9
Sep.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(9): 1532-1536
CHEN Wei, LIU Yangchun, ZHOU Congrong, LAI Fan, LI Xiaohong, LUO Erdan. Analysis on the characteristics and risk factors of spontaneous abortion of childbearing age women in Chengdu from the perspective of compound constitution[J]. Chinese Journal of General Practice, 2023, 21(9): 1532-1536. doi: 10.16766/j.cnki.issn.1674-4152.003163
Citation: CHEN Wei, LIU Yangchun, ZHOU Congrong, LAI Fan, LI Xiaohong, LUO Erdan. Analysis on the characteristics and risk factors of spontaneous abortion of childbearing age women in Chengdu from the perspective of compound constitution[J]. Chinese Journal of General Practice, 2023, 21(9): 1532-1536. doi: 10.16766/j.cnki.issn.1674-4152.003163
shu

Analysis on the characteristics and risk factors of spontaneous abortion of childbearing age women in Chengdu from the perspective of compound constitution

doi: 10.16766/j.cnki.issn.1674-4152.003163
  • 1.

    Traditional Chinese Medicine Department of Chengdu Women' s and Children' s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan 611731, China

Funds:

 2023YFG0277

 川中医药办函〔2022〕36号

 2021MS283

 2022-043

 SCYW012

  • Received Date: 2022-06-21
    Abstract
  •   Objective  To understand the compound constitution characteristics of patients with spontaneous abortion (SA), to explore the risk factors of SA in women of childbearing age, and to provide reference for the prevention of SA.  Methods  The information of pregnancy and traditional Chinese Medicine (TCM) constitution of childbearing age women who visited the TCM Department of Chengdu Women's and Children's Central Hospital in January 2016 to December 2021 were collected, and their compound constitutions were identified.Univariate analysis was used to compare the differences of major and concurrent constitutions between SA patients and non-SA people, and logistic regression model was established to explore the risk factors of SA.  Results  A total of 2 878 childbearing age women were included, and 759 of them had a history of SA, with an average age of 32.34, and only 11.86% of them were of balanced constitution, which was less than that of non-SA people (χ2=4.059, P=0.044).The proportion of SA patients with special intrinsic constitution was higher than that of non-SA people (χ2=8.542, P=0.003), and the compound constitutions containing Qi-deficiency (χ2=5.113, P=0.024) and Yang-deficiency constitution (χ2=5.724, P=0.017) were higher than non-SA population.The biased constitutions of SA patients were aggregative.Age growth, Yang-deficiency and Special Intrinsic constitutions were the risk factors of SA.  Conclusion  The proportions of Qi-deficiency and Yang-deficiency as compound constitutions in SA patients are higher than those in non-SA population, and Yang-deficiency, Qi-depression and Qi-deficiency show aggregation.Age, Yang-deficiency and special intrinsic constitutions are the risk factors of spontaneous abortion.It is suggested in clinical practice to adjust the constitution of preparing pregnant women when with Yang-deficiency and special intrinsic constitutions as soon as possible to prevent spontaneous abortion.

     

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    • References(21)
  • [1]
    自然流产诊治中国专家共识编写组.自然流产诊治中国专家共识(2020年版)[J]. 中国实用妇科与产科杂志, 2020, 36(11):1082-1090. https://www.cnki.com.cn/Article/CJFDTOTAL-XIBU202105002.htm

    Spontaneous Abortion Diagnosis and Treatment of Chinese Expert Consensus Compilation Group. Expert consensus on diagnosis and tTreatment of spontaneous abortion in China (2020 edition)[J]. Chinese Journal of Practical Gynecology and Obstetric, 2020, 36(11):1082-1090. https://www.cnki.com.cn/Article/CJFDTOTAL-XIBU202105002.htm
    [2]
    MASSALSKA D, ZIMOWSKI J G, BIJOK J, et al. First trimester pregnancy loss: clinical implications of genetic testing[J]. J Obstet Gynaecol Res, 2017, 43(1):23-29. doi: 10.1111/jog.13179
    [3]
    GREEN D M, ODONOGHUE K. A review of reproductive outcomes of women with two consecutive miscarriages and no living child[J]. J Obstet Gynaecol, 2019, 39(6):816-821. doi: 10.1080/01443615.2019.1576600
    [4]
    谢幸, 孔北华, 段涛, 等.妇产科学[M]. 9版.北京:人民卫生出版社, 2018:70-74.

    XIE X, KONG B H, DUAN T, et al. Gynecology and Obstetrics[M]. 9th Ed. Beijing: People's Medical Publishing House, 2018:70-74.
    [5]
    马渑霞, 申焕霞, 吕田甜, 等.不明原因复发性流产患者生育压力与抑郁症状间的关系:心理弹性的中介作用[J]. 中国健康心理学杂志, 2021, 29(11):1627-1631. https://www.cnki.com.cn/Article/CJFDTOTAL-JKXL202111007.htm

    MA Y X, SHEN H X, LYU T T, et al. Relationship between fertility pressure and depressive symptoms in patients with unexplained recurrent spontaneous abortion: Mediating role of psychological resilience[J]. China Journal of Health Psychology, 2021, 29(11):1627-1631. https://www.cnki.com.cn/Article/CJFDTOTAL-JKXL202111007.htm
    [6]
    郭冀丹, 李巧平, 宫敏.复发性流产孕妇的焦虑, 抑郁状况与社会支持, 家庭功能的关系[J]. 海南医学, 2020, 31(20):2651-2654. doi: 10.3969/j.issn.1003-6350.2020.20.018

    GUO J D, LI Q P, GONG M. Relationship between anxiety, depression status and social support, family function in pregnant women with recurrent miscarriage[J]. Hainan Med J, 2020, 31(20):2651-2654. doi: 10.3969/j.issn.1003-6350.2020.20.018
    [7]
    ESHRE Guideline Group on RPL, BENDER ATIK R, CHRISTIANSEN O B, et al. ESHRE guideline: recurrent pregnancy loss[J]. Human Reproduction Open, 2018(2):1-12.
    [8]
    李子贇, 佟旭, 李海玉.中医全科医学诊疗实践及发展优势[J]. 中华全科医学, 2020, 18(9):1433-1436. doi: 10.16766/j.cnki.issn.1674-4152.001526

    LI Z Y,TONG X,LI H Y. Practice and development advantages of general practice of traditional Chinese medicine[J]. Chinese Journal of General Practice, 2020, 18(9):1433-1436. doi: 10.16766/j.cnki.issn.1674-4152.001526
    [9]
    邱晓堂, 屈凯, 程亚伟.中医体质辨识与调治[M]. 上海:上海科学技术出版社, 2019:220.

    QIU X T, QU K, CHENG Y W, et al. TCM constitution identification and regulation[M]. Shanghai: Shanghai Scientific & Technical Publishers, 2019:220.
    [10]
    汪雯.基于中医体质辨识观察益肾安胎方治疗复发性流产患者的临床妊娠结局[D]. 南京:南京中医药大学, 2021.

    WANG W. Observation of clinical pregnancy outcome of Yishen Antai Recipe in the treatment of recurrent abortion based on TCM Constitution identification[D]. Nan Jing:Nanjing University of Chinese Medicine, 2021.
    [11]
    伊静.复发性流产病因与中医体质的相关性研究[D]. 晋中:山西中医药大学, 2019.

    YI J. Correlation between etiology and Chinese constitution of recurrent spontaneous abortion[D]. Jin Zhong:Shanxi University of Chinese Medicine, 2019.
    [12]
    冯晓玲, 刘禹熙, 陈璐, 等.抗心磷脂抗体阳性复发性流产患者的中医体质特点研究[J]. 广州中医药大学学报, 2019, 36(1):49-52. https://www.cnki.com.cn/Article/CJFDTOTAL-REST201901011.htm

    FENG X L, LIU Y X, CHEN L, et al. Investigation of traditional Chinese medicine constitution of anticardiolipin antibody-positive patients with recurrent spontaneous abortion[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2019, 36(1):49-52. https://www.cnki.com.cn/Article/CJFDTOTAL-REST201901011.htm
    [13]
    中华中医药学会.中医体质分类与判定[M]. 北京:中国中医药出版社, 2009.

    China Association of Traditional Chinese Medicine[M]. Beijing:China Press of Traditional Chinese Medicine, 2009.
    [14]
    中国肥胖问题工作组.中国成人超重和肥胖症预防与控制指南(节录)[J]. 营养学报, 2004(1):1-4. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXX200401004.htm

    Working Group of Chinese Obesity Problem. Guidelines for the prevention and control of overweight and obesity in Chinese adults (Excerpt)[J]. Acta Nutrimenta Sinica, 2004(1):1-4. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXX200401004.htm
    [15]
    叶平, 王欢欢, 叶骞, 等.465例自然流产患者中医体质类型分布特点的临床研究[J]. 中华中医药学刊, 2013, 31(10):2215-2217. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS201310049.htm

    YE P, WANG H H, YE Q, et al. Clinical research of TCM constitution distribution characteristics of spontaneous abortion patients[J]. Chineese Archives of Traditonal Chinese Medicine, 2013, 31(10):2215-2217. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS201310049.htm
    [16]
    闫春迪.督灸对特禀质干预作用的临床研究[D]. 济南:山东中医药大学, 2017.

    YAN C D. Clinical study on the intervention effect on allergic constitution with Du-Moxibustion[D]. Jinan:Shandong University of Chinese Medicine, 2017.
    [17]
    王欢欢.中医辨体调质对自然流产患者孕前干预的临床研究[D]. 杭州:浙江中医药大学, 2014.

    WANG H H. Clinical research on the preconceptional intervention of TCM distinguishing and regulating constitution of spontaneous abortion patients[D]. Hangzhou:Zhejiang University of Chinese Medicine, 2014.
    [18]
    黄钰景, 庄严, 李楠.习惯性流产患者的心理健康与社会支持的相关性研究[J]. 国际护理学杂志, 2021, 40(23):4244-4247.

    HUANG Y J, ZHUANG Y, LI N. Correlation between mental health and social support in patients with habitual abortion[J]. International Journal of Nursing, 2021, 40(23):4244-4247.
    [19]
    刘雁贞.心理干预对复发性流产患者分娩结局的影响[J]. 中国医药科学, 2021, 11(4):131-134. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202104041.htm

    LIU Y Z. Study on the influence of psychological intervention on delivery outcome of patients with recurrent abortion[J]. China Medicine and Pharmacy, 2021, 11(4):131-134. https://www.cnki.com.cn/Article/CJFDTOTAL-GYKX202104041.htm
    [20]
    苏娜.辨体调质联合膏方对气虚质复发性流产患者孕前干预的临床研究[D]. 济南:山东中医药大学, 2021.

    SU N. Clinical study on pre-pregnancy intervention of Bianti Tiaozhi combined ointment on recurrent spontaneous abortion patients with qi deficiency[D]. Jinan: Shandong University of Chinese Medicine, 2021.
    [21]
    李静颖, 周建平.子午流注择时耳穴压豆对改善肾虚型早期先兆流产阳虚体质及临床疗效的影响[J]. 中华全科医学, 2022, 20(3):478-481. doi: 10.16766/j.cnki.issn.1674-4152.002382

    LI J Y, ZHOU J P. Clinical effect of midnight-noon ebb-flow of ear acupoint pressing bean on improving yang-deficiency constitution and clinical curative effect of early threatened abortion with kidney-deficiency syndrome[J]. Chinese Journal of General Practice, 2022, 20(3):478-481. doi: 10.16766/j.cnki.issn.1674-4152.002382
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