Volume 21 Issue 9
Sep.  2023
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CHU Hua, LU Yan, LIU Mingsong. Predictive value of uterine artery ultrasound parameter prediction model for preeclampsia risk in early pregnancy[J]. Chinese Journal of General Practice, 2023, 21(9): 1563-1565. doi: 10.16766/j.cnki.issn.1674-4152.003171
Citation: CHU Hua, LU Yan, LIU Mingsong. Predictive value of uterine artery ultrasound parameter prediction model for preeclampsia risk in early pregnancy[J]. Chinese Journal of General Practice, 2023, 21(9): 1563-1565. doi: 10.16766/j.cnki.issn.1674-4152.003171
shu

Predictive value of uterine artery ultrasound parameter prediction model for preeclampsia risk in early pregnancy

doi: 10.16766/j.cnki.issn.1674-4152.003171

  • Department of Ultrasound, Huzhou Maternal and Child Health Hospital, Huzhou, Zhejiang 313000, China

Funds:

 2019GYB15

 2021KY1084

  • Received Date: 2023-04-11
    Available Online: 2023-10-19
    Abstract
  •   Objective  To explore the value of uterine artery ultrasound parameters in the prediction of preeclampsia at 11-13 weeks of gestation, we constructed a uterine artery ultrasound parameter prediction model at 11-13 weeks of gestation, and analyzed its prediction value for the risk of preeclampsia.  Methods  A total of 200 patients who visited Huzhou Women's and Children's Health Care Hospital in early pregnancy from May 2020 to May 2022 were included. They were divided into occurred group (100 cases) and not occurred group (100 cases) according to whether they had preeclampsia. The ultrasonic parameters of uterine artery in the 11-13 weeks of pregnancy were extracted from the electronic medical record system, and a logistic regression prediction model based on the ultrasonic parameters of uterine artery in early pregnancy was established. The ROC curve was drawn to analyze its sensitivity and specificity for predicting preeclampsia.  Results  The multivariate logistic regression analysis showed that high body mass index (BMI, OR=1.311, P<0.001), high cholesterol (OR=1.673, P=0.004), high uterine artery pulsatility index (UtA-PI, OR=1.327, P<0.001) and high resistance index (RI, OR=1.846, P=0.036) were the risk factors for preeclampsia. ROC curve showed that the AUC of the model for predicting the risk of preeclampsia was 0.762 (95% CI: 0.696-0.819), the sensitivity was 81.00%, and the specificity was 63.00%.  Conclusion  The prediction model based on uterine artery ultrasound parameters UtA-PI, RI, high BMI and cholesterol in early pregnancy can be used for the prediction of preeclampsia.

     

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    • References(15)
  • [1]
    王媛, 唐慧荣, 王娅, 等. 孕期血压与妊娠期高血压或子痫前期发病关系的研究[J]. 中华妇产科杂志, 2021, 56(11): 767-773. doi: 10.3760/cma.j.cn112141-20210601-00297

    WANG Y, TANG H R, WANG Y. Association between gestational blood pressure and pregnancy induced hypertension or pre-eclampsia[J]. 中华妇产科杂志, 2021, 56(11): 767-773. doi: 10.3760/cma.j.cn112141-20210601-00297
    [2]
    杨春丽, 杨敬敬. 超声子宫动脉搏动指数联合血清HMGB1、sCD40L对子痫前期孕妇的预测价值[J]. 中国临床医学影像杂志, 2021, 32(7): 513-516.

    YANG C L, YANG J J. Value of uterine artery Doppler pulsatility index combined with serum HMGB1 and sCD40L in predicting preeclampsia[J]. Journal of China Clinic Medical Imaging, 2021, 32(7): 513-516.
    [3]
    GANA N, SARNO M, VIEIRA N, et al. Ophthalmic artery Doppler at 11-13 weeks' gestation in prediction of pre-eclampsia[J]. Ultrasound Obstet Gynecol, 2022, 59(6): 731-736. doi: 10.1002/uog.24914
    [4]
    WAIRACHPANICH V, PHUPONG V. Second-trimester serum high mobility group box-1 and uterine artery Doppler to predict preeclampsia[J]. Sci Rep, 2022, 12(1): 6886. DOI: 10.1038/s41598-022-10861-1.
    [5]
    PLASENCIA W, MAIZ N, POON L, et al. Uterine artery Doppler at 11 + 0 to 13 + 6 weeks and 21 + 0 to 24 + 6 weeks in the prediction of pre-eclampsia[J]. Ultrasound Obstet Gynecol, 2008, 32(2): 138-146. doi: 10.1002/uog.5402
    [6]
    张翼, 刘兴会. 子痫前期的主要生物标志物预测指标及其评价[J]. 实用妇产科杂志, 2021, 37(11): 803-807. doi: 10.3969/j.issn.1003-6946.2021.11.syfckzz202111002

    ZHANG Y, LIU X H. Prediction of major biomarkers of preeclampsia and its evaluation[J]. Journal of Practical Obstetrics and Gynecology, 2021, 37(11): 803-807. doi: 10.3969/j.issn.1003-6946.2021.11.syfckzz202111002
    [7]
    吕鑫, 张为远, 张靖霄, 等. 早发与晚发子痫前期高危因素的对比分析[J]. 中华妇产科杂志, 2021, 56(11): 760-766. doi: 10.3760/cma.j.cn112141-20210330-00164

    LYU X, ZHANG W Y, ZHANG J X. Comparative analysis of high risk factors between early-onset pre-eclampsia and late-onset pre-eclampsia[J]. Chinese Journal of Obstetrics and Gynecology, 2021, 56(11): 760-766. doi: 10.3760/cma.j.cn112141-20210330-00164
    [8]
    孙秀荣, 张杰生, 邓宇傲. 指端容积血流脉动波、子宫动脉多普勒联合sFlt-1/PlGF比值对早发型子痫前期的预测[J]. 湖南师范大学学报(医学版), 2021, 18(3): 31-35. doi: 10.3969/j.issn.1673-016X.2021.03.009

    SUN X R, ZHANG J S, DENG Y A. The predictive value of combined detection of uterine artery ultrasound, photoplethysmography and sFlt-1/PlGF for early onset preeclampsia[J]. Journal of Hunan Normal University(Medical Science), 2021, 18(3): 31-35. doi: 10.3969/j.issn.1673-016X.2021.03.009
    [9]
    谢彬, 李傲霜, 万红芳, 等. 外周血LOX-1、PAPP-A联合超声检查子宫动脉PI对子痫前期的预测价值[J]. 临床误诊误治, 2021, 34(3): 96-100.

    XIE B, LI A S, WANG H F, et al. Predictive Value of LOX-1 and PAPP-A in Peripheral Blood Combined with PI as Derived from Ultrasoundfor Pre-eclampsia[J]. Clinical Misdiagnosis & Mistherapy, 2021, 34(3): 96-100.
    [10]
    CLARK A R, JAMES J L, STEVENSON G N, et al. Understanding abnormal uterine artery Doppler waveforms: a novel computational model to explore potential causes within the utero-placental vasculature[J]. Placenta, 2018, 66(1): 74-81.
    [11]
    EL-SAYED A. Preeclampsia: a review of the pathogenesis and possible management strategies based on its pathophysiological derangements[J]. Taiwan J Obstet Gynecol, 2017, 56(5): 593-598. doi: 10.1016/j.tjog.2017.08.004
    [12]
    PETURSDOTTIR M H, SUNDSTROM P I, LINDSTROM L, et al. Ultrasound estimated subcutaneous and visceral adipose tissue thicknesses and risk of pre-eclampsia[J]. Sci Rep, 2021, 11(1): 22740. DOI: 10.1038/s41598-021-02208-z.
    [13]
    KALAFAT E, LAORETI A, KHALIL A, et al. Ophthalmic artery Doppler for prediction of pre-eclampsia: systematic review and meta-analysis[J]. Ultrasound Obstet Gynecol, 2018, 51(6): 731-737. doi: 10.1002/uog.19002
    [14]
    储华, 陆艳, 刘明松. 孕期子宫动脉超声参数动态分析与子痫前期风险的相关性研究[J]. 中华全科医学, 2022, 20(9): 1545-1547, 1582. doi: 10.16766/j.cnki.issn.1674-4152.002645

    CHU H, LU Y, LIU M S. The correlation between the dynamic analysis of uterine artery ultrasound parameters during pregnancy and the risk of preeclampsia[J]. Chinese Journal of General Practice, 2022, 20(9): 1545-1547, 1582. doi: 10.16766/j.cnki.issn.1674-4152.002645
    [15]
    ANTONIC T D, ARDALIC D Č, VLADIMIROV S S, et al. Cholesterol homeostasis is dysregulated in women with preeclampsia[J]. Pol Arch Intern Med, 2021, 131(12): 16144. DOI: 10.20452/pamw.16144.
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