Volume 21 Issue 10
Oct.  2023
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LIU Zhiyu, CAO Chang, CHEN Xi, XU Ruochen, ZHENG Yingying, SHANGGUAN Jiahong, TANG Junnan, ZHANG Jinying. Analysis of the treatment effect of percutaneous balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension[J]. Chinese Journal of General Practice, 2023, 21(10): 1647-1650. doi: 10.16766/j.cnki.issn.1674-4152.003190
Citation: LIU Zhiyu, CAO Chang, CHEN Xi, XU Ruochen, ZHENG Yingying, SHANGGUAN Jiahong, TANG Junnan, ZHANG Jinying. Analysis of the treatment effect of percutaneous balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension[J]. Chinese Journal of General Practice, 2023, 21(10): 1647-1650. doi: 10.16766/j.cnki.issn.1674-4152.003190

Analysis of the treatment effect of percutaneous balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension

doi: 10.16766/j.cnki.issn.1674-4152.003190
Funds:

 82000238

 81870328

 202300410362

  • Received Date: 2022-10-20
    Available Online: 2023-11-23
  •   Objective  To evaluate the efficacy and safety of balloon pulmonary angioplasty (BPA) in a cohort of patients with pulmonary hypertension due to chronic thrombotic and/or embolic disease (CTEPH).  Methods  From October 2019 to June 2022, 8 patients diagnosed with CTEPH at the First Affiliated Hospital of Zhengzhou University underwent BPA surgery. The basic clinical characteristics of the patients were collected, and the hemodynamic indexes, improvement of cardiac structure, and surgical complications were observed.  Results  There were 5 female and 3 male patients. The mean age at presentation was (55.25±10.45) years, and the mean progressed period of CTEPH was (10.87±6.10) months, and the average follow-up duration was (255.50±149.71) days. A total of 46 BPA operations were performed, with one hemoptysis complication occurred in a patient with Takayasu' s arteritis, and the average number of BPA operations was (5.75±3.57) times. Mean pulmonary artery pressure after BPA decreased from (92.25±33.59) mmHg (1 mmHg=0.133 kPa) to (53.87±27.58) mmHg (P=0.022). NT-proBNP, cardiac output, cardiac index, tricuspid regurgitation velocity, EDV and NYHA were significantly improved (all P < 0.05). When cardiac structural parameters were compared before BPA surgery, before discharge and at follow-up, right ventricular diameter, left ventricular diameter, and right atrial upper and lower diameter were all improved (all P < 0.05).  Conclusion  BPA is a new surgical technique that can improve hemodynamic indexes and cardiac structure in CTEPH patients with fewer complications.

     

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