Volume 21 Issue 10
Oct.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(10): 1686-1688
DOU Yuxiao, HU Xuefeng, XU Jian. Rationality analysis of perioperative antibiotics in neurosurgery of a general hospital[J]. Chinese Journal of General Practice, 2023, 21(10): 1686-1688. doi: 10.16766/j.cnki.issn.1674-4152.003201
Citation: DOU Yuxiao, HU Xuefeng, XU Jian. Rationality analysis of perioperative antibiotics in neurosurgery of a general hospital[J]. Chinese Journal of General Practice, 2023, 21(10): 1686-1688. doi: 10.16766/j.cnki.issn.1674-4152.003201
shu

Rationality analysis of perioperative antibiotics in neurosurgery of a general hospital

doi: 10.16766/j.cnki.issn.1674-4152.003201
  • 1.

    Pharmacy Department of the Eighth People's Hospital of Hefei, Hefei, Anhui 238000, China

Funds:

 KJ2021A0801

  • Received Date: 2023-06-28
    Available Online: 2023-11-23
    Abstract
  •   Objective  To evaluate the appropriateness of perioperative prophylactic antibiotic use in neurosurgery department of the Eighth People's Hospital of Hefei.  Methods  Using the hospital information system, 62 surgical patients admitted to the Department of Neurosurgery from January to December 2022 were randomly selected to evaluate and analyze their perioperative prophylactic antibiotic use. The main evaluation contents included the selection of antibiotics (the first and second generation Cephalosporin or Ceftriaxone, of which the first generation Cephalosporin recommended Cefazolin, and the second generation Cephalosporin recommended Cefuroxime), indications (it is recommended to use prophylactic antibiotics in the perioperative period for patients undergoing craniocerebral surgery, and routine use of prophylactic antibiotics is not recommended for Neurosurgery operations without intracranial access such as facial nerve microvascular decompression, scalp Benign tumor resection, etc.), dosage, timing of first prophylactic drug administration and duration of antimicrobial use.  Results  The age of 62 patients was (65.52±14.31) years, including 45 males (72.58%) and 17 females (27.42%). Among the 62 patients, 61 cases (98.39%) had Class Ⅰ incision and 1 case (1.61%) had Class Ⅱ incision. Seven patients (11.29%) unnecessarily prolonged the duration of postoperative prophylaxis; 19 patients (30.65%) had an inappropriate timing for the first preventive medication; There were 7 patients (11.29%) without indications for prophylactic use of antibiotics; Of all enrolled patients, only 29 cases (46.77%) were appropriate in all the evaluation indicators of perioperative prophylactic use of antibiotics in neurosurgery.  Conclusion  There are some deficiencies in the prophylactic use of antibiotics to prevent incision site infection in the neurosurgery department of the Eighth People's Hospital of Hefei. It is necessary to further strengthen the publicity and management of rational use of antibiotics.

     

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