Volume 21 Issue 11
Nov.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(11): 1818-1822
XU Fei, DOU Qiangbing, LI Xingxing, ZHENG Quan, WANG Qiwei, SUN Liangye. Analysis of influencing factors of vertebroplasty in the treatment of senile vertebral compression fracture[J]. Chinese Journal of General Practice, 2023, 21(11): 1818-1822. doi: 10.16766/j.cnki.issn.1674-4152.003232
Citation: XU Fei, DOU Qiangbing, LI Xingxing, ZHENG Quan, WANG Qiwei, SUN Liangye. Analysis of influencing factors of vertebroplasty in the treatment of senile vertebral compression fracture[J]. Chinese Journal of General Practice, 2023, 21(11): 1818-1822. doi: 10.16766/j.cnki.issn.1674-4152.003232
shu

Analysis of influencing factors of vertebroplasty in the treatment of senile vertebral compression fracture

doi: 10.16766/j.cnki.issn.1674-4152.003232
  • 1.

    Graduate School of Bengbu Medical College, Bengbu, Anhui 233000, China

Funds:

 82102629

 AHWJ2022c043

  • Received Date: 2023-06-09
    Available Online: 2024-01-13
    Abstract
  •   Objective   To analyze the factors affecting the effect of vertebroplasty on senile vertebral compression fracture, in order to estimate the postoperative efficacy of patients and intervene in advance if necessary to improve the effectiveness of treatment.   Methods   A retrospective study was conducted on 307 elderly patients with vertebral compression fracture who were admitted to the Department of Orthopedics of Lu' an People' s Hospital from January 2015 to June 2022 and received vertebroplasty. Patients were divided into effective group (n=257) and ineffective group (n=50) according to the improvement rate of the Japanese Orthopaedic Association score (JOA score). Gender, age, surgical methods, serum Mg2+ concentration, bone cement touch the upper and lower endplates, shape of bone cement, part of bone cement, bone cement covering fracture line and edema area, osteoporosis, and old fracture were summarized and analyzed. Multivariate logistic regression was used to analyze the related factors affecting the curative effect.   Results   There was a positive correlation between cement not involving the upper and lower endplates, cement being "O" shaped, cement being distributed in the posterior 2/3 of the vertebral body, cement not covering the fracture line and oedema area, and osteoporosis and poor efficacy of vertebral compression fractures treated with vertebroplasty, and the differences were statistically significant (all P<0.05). There were no significant differences of gender, age, decrease in serum Mg2+ concentration, old fracture or not (all P>0.05). Cement not involving the upper and lower endplates (OR=9.188, P=0.034), cement being "O" shaped (OR=29.274, P<0.001), cement being distributed in the posterior 2/3 of the vertebral body (OR=24.928, P=0.001), and cement not covering the fracture line and oedema area (OR=16.357, P=0.045) were independent risk factors affecting their efficacy.   Conclusion   Bone cement don' t touch the upper and lower endplates, "O" type of bone cement, distribution of bone cement in the posterior 2/3 of the centrum, and the failure of bone cement to cover the fracture line and edema area are independent risk factors for therapeutic effect.

     

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