Volume 22 Issue 2
Feb.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(2): 304-307
WANG Huanfen, LIU Wei, CHEN Saiya, CHEN Meilan. Study on the treatment of lower limb muscle spasms after stroke using botulinum toxin A injection combined with spasmodic electromyography stimulation[J]. Chinese Journal of General Practice, 2024, 22(2): 304-307. doi: 10.16766/j.cnki.issn.1674-4152.003390
Citation: WANG Huanfen, LIU Wei, CHEN Saiya, CHEN Meilan. Study on the treatment of lower limb muscle spasms after stroke using botulinum toxin A injection combined with spasmodic electromyography stimulation[J]. Chinese Journal of General Practice, 2024, 22(2): 304-307. doi: 10.16766/j.cnki.issn.1674-4152.003390
shu

Study on the treatment of lower limb muscle spasms after stroke using botulinum toxin A injection combined with spasmodic electromyography stimulation

doi: 10.16766/j.cnki.issn.1674-4152.003390

  • Department of Geriatrics, Wenzhou Traditional Chinese Medicine Hospital, Wenzhou, Zhejiang 325000, China

Funds:

 2023KY1159

  • Received Date: 2023-10-12
    Available Online: 2024-03-27
    Abstract
  •   Objective  To enhance the treatment options for post-stroke muscle spasms and improve the quality of life of stroke patients, the clinical effect of combining botulinum toxin A injection with spasmodic electromyography stimulation for the rehabilitation of post-stroke lower limb muscle spasms were explored.  Methods  A total of 140 patients with lower limb muscle spasms after stroke who were admitted to Wenzhou Traditional Chinese Medicine Hospital between February 2020 and February 2023 were enrolled. The 70 cases in the observation group and the 70 cases in the control group were randomly divided into two groups using a random number table method. All patients underwent rehabilitation training, The control group received injection of type A botulinum toxin, while the observation group received additional treatment with spasmodic electromyographic stimulation. The study evaluated the therapeutic effect of interventions on lower limb muscle spasms in patients, comparing the levels before and after the intervention. The lower limb muscle ' s motor unit action potential (MUAP) count was measured. The study evaluated the level of motor function and living ability, as well as changes in ultrasonic indexes of gastrocnemius muscle structure.  Results  The research group achieved a significantly higher overall effective rate of lower limb muscle spasm treatment (94.29%, 66/70) compared to the control group (81.43%, 57/70), χ2=5.423, P=0.020. Following the intervention, the number of MUAP in the triceps surae of the observation group (10.92±1.74) was significantly lower than that of the control group (14.86±1.85, t=12.979, P < 0.001). Following the intervention, the scores for Fugl-Meyer assessment scale (FMA), functional ambulation category scale (FAC), and modified Barthel index (MBI) were significantly higher in the observation group than in the control group (P < 0.001). Following the intervention, the observation group exhibited lower PA and MT values of in the lower limb gastrocnemius muscle compared to the control group. Conversely, the FL and MT values were higher in the observation group than in the control group (P < 0.001).  Conclusion  The combination of spastic myoelectric stimulation and botulinum toxin A therapy can enhance the therapeutic effect of lower limb muscle spasms after stroke. It can also alleviate the severity of lower limb muscle spasms, promote the recovery of affected limb muscle structure and function, and improve patients ' motor ability and quality of life.

     

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