Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus

CHEN Weier; QIU Yan; PAN Xiaohua; YE Yun; REN Jingjing

doi:10.16766/j.cnki.issn.1674-4152.003460

Volume 22 Issue 4

Apr. 2024

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Article Navigation > Chinese Journal of General Practice > 2024 > 22(4): 601-604

CHEN Weier, QIU Yan, PAN Xiaohua, YE Yun, REN Jingjing. Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus[J]. Chinese Journal of General Practice, 2024, 22(4): 601-604. doi: 10.16766/j.cnki.issn.1674-4152.003460

Citation:

CHEN Weier, QIU Yan, PAN Xiaohua, YE Yun, REN Jingjing. Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus[J]. Chinese Journal of General Practice, 2024, 22(4): 601-604. doi: 10.16766/j.cnki.issn.1674-4152.003460

Citation:

CHEN Weier, QIU Yan, PAN Xiaohua, YE Yun, REN Jingjing. Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus[J]. Chinese Journal of General Practice, 2024, 22(4): 601-604. doi: 10.16766/j.cnki.issn.1674-4152.003460

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Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus

doi: 10.16766/j.cnki.issn.1674-4152.003460

CHEN Weier^{1, 2}
, QIU Yan¹
, PAN Xiaohua²
, YE Yun³
, REN Jingjing^{1
,
,}

1.
Department of General Practice, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, China

Funds:

2020ZYC-A119

2020ZHA-KEB323

Received Date: 2023-11-03
Available Online: 2024-05-29

Abstract

Abstract

Objective The study aimed to assess the medication compliance status in hypertensive patients combined with diabetes mellitus and to explore the influencing factors based on socio-demographic characteristics, lifestyle behaviors, and medical records. Methods Between November 2021 and March 2022, a total of 381 patients from four community hospitals in Ningbo were randomly selected as participants. They were surveyed using a questionnaire based on the Chinese version of the 8-item Morisky medication adherence scale (MMAS-8). Binary logistic analysis was used for data analysis. Results The average medication adherence score for 381 patients combined hypertension and diabetes mellitus was (5.67±1.05) points, with 163 patients (42.78%) demonstrating high adherence. Univariate analysis revealed that significant associations between medication adherence and various factors, including gender, medical payment methods, daily medication types, daily medication frequency, and alcohol consumption (P < 0.05). Multiple logistic regression revealed that patients with medical insurance for urban workers payment had higher medication compliance (OR=2.141, 95% CI: 1.346-3.405, P=0.001). Additionally, patients with a daily medication frequency of ≥3 (OR=0.438, 95% CI: 0.208-0.921, P=0.030) and those with daily medication types ≥3 (OR=0.342, 95% CI: 0.216-0.540, P < 0.001) exhibited lower medication compliance. Conclusion The medication compliance among patients with combined hypertension and diabetes mellitus is suboptimal, primarily influenced by factors such as daily medication frequency, daily medication types, and medical payment methods. Therefore, proactive interventions should be implemented based on these influencing factors.
- Hypertension,
- Diabetes mellitus,
- Multimorbidity,
- Medication adherence,
- Influencing factors

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References(22)

References

[1]	陈维尔, 邱艳, 潘晓华, 等. 我国共病患者服药依从性的研究进展[J]. 中华全科医学, 2023, 21(10): 1745-1748. doi: 10.16766/j.cnki.issn.1674-4152.003215 CHEN W E, QIU Y, PAN X H, et al. Progress on medication compliance of patients with multimorbidity in China[J]. Chinese Journal of General Practice, 2023, 21(10): 1745-1748. doi: 10.16766/j.cnki.issn.1674-4152.003215
[2]	豆丽园, 黄娟, 叶森, 等. 社区老年慢性病共存患者治疗负担现状及影响因素研究[J]. 中国全科医学, 2021, 24(13): 1671-1675. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202113015.htm DOU L Y, HUANG J, YE S, et al. Treatment Burden and Influencing Factors of Elderly Patients with Multimorbidity in the Community[J]. Chinese General Practice, 2021, 24(13): 1671-1675. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202113015.htm
[3]	杨直, 高静, 柏丁兮, 等. 老年慢性病共病患者治疗负担体验的质性研究[J]. 中国全科医学, 2022, 25(19): 2336-2341. doi: 10.12114/j.issn.1007-9572.2022.0169 YANG Z, GAO J, BAI D X, et al. Experience of treatment burden in older adults with multimorbidity: a qualitative study[J]. Chinese General Practice, 2022, 25(19): 2336-2341. doi: 10.12114/j.issn.1007-9572.2022.0169
[4]	张强, 王长远, 李一凡. 老年慢性病共病患者抑郁焦虑状况及影响因素[J]. 安徽医学, 2023, 44(3): 257-261. doi: 10.3969/j.issn.1000-0399.2023.03.003 ZHANG Q, WANG C Y, LI Y F. Analysis of depression anxiety and influencing factors in elderly patients with chronic comorbidity[J]. Anhui Medical Journal, 2023, 44(3): 257-261. doi: 10.3969/j.issn.1000-0399.2023.03.003
[5]	MAIR A, WILSON M, DREISCHULTE T. Addressing the challenge of Polypharmacy[J]. Annu Rev Pharmacol Toxicol, 2020, 60: 661-681. doi: 10.1146/annurev-pharmtox-010919-023508
[6]	姚元龙, 史威力, 冯娴, 等. 老年共病的研究管理策略[J]. 中华全科医学, 2022, 20(8): 1267-1270. doi: 10.16766/j.cnki.issn.1674-4152.002574 YAO Y L, SHI W L, FENG X, et al. Research management strategies for multimorbidity in elderly patients[J]. Chinese Journal of General Practice, 2022, 20(8): 1267-1270. doi: 10.16766/j.cnki.issn.1674-4152.002574
[7]	范潇茹, 陈莎, 施予宁, 等. 我国中老年人慢性病共病现状及其对卫生服务利用和医疗费用的影响研究[J]. 中国全科医学, 2022, 25(19): 2371-2378. doi: 10.12114/j.issn.1007-9572.2022.0220 FAN X R, CHEN S, SHI Y N, et al. Multimorbidity prevalence and its association with health service utilization and medical costs among middle-aged and older Chinese people[J]. Chinese General Practice, 2022, 25(19): 2371-2378. doi: 10.12114/j.issn.1007-9572.2022.0220
[8]	ZHANG Y Q, LI Y, DONG Y G, et al. A nationwide assessment of blood pressure control and the associated factors in Chinese type 2 diabetes mellitus patients[J]. J Clin Hypertens(Greenwich), 2019, 21(11): 1654-1663. doi: 10.1111/jch.13675
[9]	王登炜, 方欣, 杨泽, 等. 福建省35~75岁居民高血压合并糖尿病流行现况及影响因素[J]. 中华高血压杂志, 2023, 31(5): 461-464. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGGZ202305011.htm WANG D W, FANG X, YANG Z, et al. Prevalence and influencing factors of hypertension combined with diabetes among population aged 35-75 years in Fujian Province[J]. Chinese Journal of Hypertension, 2023, 31(5): 461-464. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGGZ202305011.htm
[10]	谭兰兰, 雷玉华. 高血压合并2型糖尿病患者残余胆固醇与血压变异性的相关性分析[J]. 中国医药, 2022, 17(10): 1468-1472. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYG202210007.htm TAN L L, LEI Y H. Correlation between residual cholesterol and blood pressure variability in hypertensive patients with type 2 diabetes mellitus[J]. China Medicine, 2022, 17(10): 1468-1472. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYG202210007.htm
[11]	张振香, 何福培, 张春慧, 等. 慢性病共病患者服药依从性潜在类别及其影响因素分析[J]. 中国全科医学, 2022, 25(31): 3904-3913. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202231010.htm ZHANG Z X, HE F P, ZHANG C H, et al. Latent class analysis and influencing factors of medication adherence in multiple chronic conditions patients[J]. Chinese General Practice, 2022, 25(31): 3904-3913. https://www.cnki.com.cn/Article/CJFDTOTAL-QKYX202231010.htm
[12]	田勇, 张楠, 杨正强, 等. 北京市怀柔区"五维一体"慢病管理模式的效果分析[J]. 北京医学, 2023, 45(4): 294-298, 303. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX202304004.htm TIAN Y, ZHANG N, YANG Z Q, et al. Analysis of management effect of "five-dimensional integration" chronic disease management model in Huairou district of Beijing[J]. Beijing Medical Journal, 2023, 45(4): 294-298, 303. https://www.cnki.com.cn/Article/CJFDTOTAL-BJYX202304004.htm
[13]	JÜNGST C, GRǍBER S, SIMONS S, et al. Medication adherence among patients with chronic diseases: a survey-based study in pharmacies[J]. QJM, 2019, 112(7): 505-512. doi: 10.1093/qjmed/hcz058
[14]	KIM S, BENNETT K, WALLACE E, et al. Measuring medication adherence in older community-dwelling patients with multimorbidity[J]. Eur J Clin Pharmacol, 2018, 74(3): 357-364. doi: 10.1007/s00228-017-2388-y
[15]	姚媛英. 社区老年共病患者服药依从性及影响因素研究[D]. 开封: 河南大学, 2018. YAO Y Y. The study on medication adherence adherence and influencing factors of community elderly patients with comorbidity[D]. Kaifeng: Henan University, 2018.
[16]	缪琴, 刘竟芳. 长沙市城区老年慢性病患者服药依从性影响因素研究[J]. 中南药学, 2019, 17(10): 1783-1787. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNYX201910045.htm MIAO Q, LIU J F. Influence factors for medication compliance in elderly patients with chronic diseases in Changsha[J]. Central South Pharmacy, 2019, 17(10): 1783-1787. https://www.cnki.com.cn/Article/CJFDTOTAL-ZNYX201910045.htm
[17]	向富森, 王佩佩, 赵治红, 等. 西安地区慢性病患者服药依从性调查及影响因素研究[J]. 华南预防医学, 2022, 48(9): 1146-1149. https://www.cnki.com.cn/Article/CJFDTOTAL-GDWF202209029.htm XIANG F S, WANG P P, ZHAO Z H, et al. Compliance and its influencing factors of patients with chronic diseases in Xi'an[J]. South China Journal of Preventive Medicine, 2022, 48(9): 1146-1149. https://www.cnki.com.cn/Article/CJFDTOTAL-GDWF202209029.htm
[18]	保琦, 罗震寰, 翟琛琛, 等. 我国6省7家县级公立医院高血压患者用药依从性及影响因素研究[J]. 中国药事, 2021, 35(2): 206-214. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYS202102013.htm BAO Q, LUO Z H, ZHAI C C, et al. Research on medication adherence and impact factors of hypertension patients in 7 county-level public hospitals in 6 provinces in China[J]. Chinese Pharmaceutical Affairs, 2021, 35(2): 206-214. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYS202102013.htm
[19]	李立荣. 社区慢性病患者服药依从性的调查及对策[J]. 中国社区医师, 2022, 38(2): 7-9. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYS202202003.htm LI L R. Investigation and countermeasures on medication compliance of chronic disease patients in community[J]. Chinese Community Doctors, 2022, 38(2): 7-9. https://www.cnki.com.cn/Article/CJFDTOTAL-XCYS202202003.htm
[20]	田雪莹, 张丙银, 侯家祥, 等. 山东省农村地区高血压患者服药依从性影响因素研究[J]. 预防医学论坛, 2020, 26(10): 732-735. https://www.cnki.com.cn/Article/CJFDTOTAL-YXWX202010006.htm TIAN X Y, ZHANG B Y, HOU J X, et al. Study on influencing factors of medication compliance among hypertension patients in rural areas, Shandong province[J]. Preventive Medicine Tribune, 2020, 26(10): 732-735. https://www.cnki.com.cn/Article/CJFDTOTAL-YXWX202010006.htm
[21]	余灵芝, 袁红梅. 维持性血液透析合并高血压患者降压药服药依从性及影响因素分析[J]. 中国慢性病预防与控制, 2020, 28(10): 770-773. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMXB202010016.htm YU L Z, YUAN H M. Analysis of antihypertensive medication compliance and influencing factors in patients with maintenance hemodialysis combined with hypertension[J]. Chinese Journal of Prevention and Control of Chronic Diseases, 2020, 28(10): 770-773. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMXB202010016.htm
[22]	WORMALL S, ABBOT S. Primary care clinical pharmacists and chronic disease medication adherence[J]. Br J Gen Pract, 2021, 71(712): 496. DOI: 10.3399/bjgp21X717485.

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Analysis of medication adherence and influencing factors in hypertensive patients combined with diabetes mellitus

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