Volume 22 Issue 6
Jun.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(6): 991-994
TAN Jie, CHEN Manman, CHEN Lingyun, HUANG Yuli. Study on the influence factors of frailty and the construction of risk prediction model in elderly inpatients with chronic heart failure[J]. Chinese Journal of General Practice, 2024, 22(6): 991-994. doi: 10.16766/j.cnki.issn.1674-4152.003551
Citation: TAN Jie, CHEN Manman, CHEN Lingyun, HUANG Yuli. Study on the influence factors of frailty and the construction of risk prediction model in elderly inpatients with chronic heart failure[J]. Chinese Journal of General Practice, 2024, 22(6): 991-994. doi: 10.16766/j.cnki.issn.1674-4152.003551
shu

Study on the influence factors of frailty and the construction of risk prediction model in elderly inpatients with chronic heart failure

doi: 10.16766/j.cnki.issn.1674-4152.003551
  • 1.

    Department of Cardiovascular Medicine, the Fifth People' s Hospital of Fuyang, Fuyang, Anhui 236000, China

Funds:

 SK2020A0351

  • Received Date: 2023-09-21
    Available Online: 2024-07-22
    Abstract
  •   Objective  To explore the influencing factors of frailty in elderly patients with chronic heart failure, and build a frailty risk prediction model to provide clinical reference for preventing and reducing frailty.  Methods  A total of 198 elderly patients with chronic heart failure who were hospitalized in the cardiovascular Department of the Fifth People ' s Hospital of Fuyang from March 2022 to March 2023 were selected by convenience sampling method. They were divided into a frailty group and a non-frailty group according to whether frailty occurred. The influencing factors of frailty were analyzed by binary Logistic regression. Hosmer-Lemeshow test and ROC curve were used to detect the goodness of fit and prediction effect respectively.  Results  The incidence of frailty in elderly CHF patients was 32.32% (64/198), and fatigue was the main symptom (51.01%, 101/198). Age (OR=1.101, P=0.007), NYHA cardiac function grade (OR=2.550, P=0.011), course of disease (OR=2.210, P=0.014), sleep state (OR=2.215, P=0.010), N-terminal brain natriuretic peptide precursor (OR=1.003, P < 0.001), left ventricular ejection fraction (OR=0.910, P < 0.001) and self-management level (OR=0.229, P < 0.001) were influencing factors in the occurrence of frailty. The regression model had good goodness of fit (χ2=2.915, P=0.940), and the AUC under the ROC curve was 0.913 (P < 0.001, 95% CI: 0.870-0.956), sensitivity was 89.1%, specificity was 81.3%.  Conclusion  The incidence of frailty in elderly patients with chronic heart failure is high. Clinical attention should be paid to elderly patients with poor heart function, long course of disease, poor sleep quality, and low self-management ability. The frailty risk prediction model established in this study is effective in elderly patients with chronic heart failure, which can provide a reference for frailty risk assessment and intervention.

     

    • FullText(HTML)
  • loading
    • References(25)
  • [1]
    DING H, JAYASENA R, CHEN S H, et al. The effects of telemonitoring on patient compliance with self-management recommendations and outcomes of the innovative telemonitoring enhanced care program for chronic heart failure: randomized controlled trial[J]. J Med Internet Res, 2020, 22(7): e17559. DOI: 10.2196/17559.
    [2]
    PACKER M, ANKER S D, BUTLER J, et al. Influence of neprilysin inhibition on the efficacy and safety of empagliflozin in patients with chronic heart failure and a reduced ejection fraction: the EMPEROR-Reduced trial[J]. Eur Heart J, 2021, 42(6): 671-680. doi: 10.1093/eurheartj/ehaa968
    [3]
    张锦香, 邓力, 冯津萍, 等. 营养状况与老年女性慢性心力衰竭生存质量相关性研究[J]. 中华老年心脑血管病杂志, 2020, 22(5): 466-469. doi: 10.3969/j.issn.1009-0126.2020.05.006

    ZHANG J X, DENG L, FENG J P, et al. Relationship between nutritional status and quality of life in elderly female CHF patients[J]. Chin J Geriatr Heart Brain Vessel Dis, 2020, 22(5): 466-469. doi: 10.3969/j.issn.1009-0126.2020.05.006
    [4]
    张艳超, 翟玉民. 血清胱抑素C及糖类抗原125对老年慢性心力衰竭患者预后的评估[J]. 中华老年心脑血管病杂志, 2019, 21(2): 137-140. doi: 10.3969/j.issn.1009-0126.2019.02.007

    ZHANG Y C, ZHAI Y M. Value of serum Cys-C and CA-125 levels in predicting the outcome of elderly chronic heart failure patients[J]. Chin J Geriatr Heart Brain Vessel Dis, 2019, 21(2): 137-140. doi: 10.3969/j.issn.1009-0126.2019.02.007
    [5]
    PANDEY A, SEGAR M W, SINGH S, et al. Frailty status modifies the efficacy of exercise training among patients with chronic heart failure and reduced ejection fraction: an analysis from the HF-ACTION trial[J]. Circulation, 2022, 146(2): 80-90. doi: 10.1161/CIRCULATIONAHA.122.059983
    [6]
    杨琦琦, 孙颖, 邢云利, 等. 老年射血分数保留心力衰竭患者合并衰弱情况及其影响因素研究[J]. 中国全科医学, 2021, 24(11): 1354-1358, 1364. doi: 10.12114/j.issn.1007-9572.2021.00.411

    YANG Q Q, SUN Y, XING Y L, et al. Frailty prevalence and associated factors in elderly heart failure patients with preserved ejection fraction[J]. Chinese General Practice, 2021, 24(11): 1354-1358, 1364. doi: 10.12114/j.issn.1007-9572.2021.00.411
    [7]
    陈力量, 冯小利, 殷兰芳, 等. 老年慢性心力衰竭病人衰弱综合征临床特点及相关危险因素分析[J]. 蚌埠医学院学报, 2022, 47(3): 326-329. https://www.cnki.com.cn/Article/CJFDTOTAL-BANG202203013.htm

    CHEN L L, FENG X L, YIN L F, et al. Analysis of the clinical characteristics and risk factors of frailty syndrome in elderly patients with chronic heart failure[J]. J Bengbu Med Coll, 2022, 47(3): 326-329. https://www.cnki.com.cn/Article/CJFDTOTAL-BANG202203013.htm
    [8]
    王华, 梁延春. 中国心力衰竭诊断和治疗指南2018[J]. 中华心血管病杂志, 2018, 46(10): 760-789. doi: 10.3760/cma.j.issn.0253-3758.2018.10.004

    WANG H, LIANG Y C. Chinese Guidelines for Diagnosis and Treatment of Heart Failure 2018[J]. Chinese Journal of Cardiovascular Disease, 2018, 46(10): 760-789. doi: 10.3760/cma.j.issn.0253-3758.2018.10.004
    [9]
    张玉莲, 牛亚琦, 王丹, 等. 2019年ICFSR国际临床实践指南解读及对我国老年人衰弱识别及管理的启示[J]. 护理研究, 2020, 34(14): 2433-2436. doi: 10.12102/j.issn.1009-6493.2020.14.001

    ZHANG Y L, NIU Y Q, WANG D, et al. Interpretation of 2019 ICFSR International Clinical Practice Guidelines and its enlightenments to identification and management of frailty in the elderly people in China[J]. Chinese Nursing Research, 2020, 34(14): 2433-2436. doi: 10.12102/j.issn.1009-6493.2020.14.001
    [10]
    李涤凡, 尹德荣, 黄文伶, 等. 老年慢性心力衰竭患者自我管理现况调查和影响因素的研究[J]. 中国护理管理, 2020, 20(3): 360-366. doi: 10.3969/j.issn.1672-1756.2020.03.010

    LI D F, YIN D R, HUANG W L, et al. Investigation of self-management behaviors and its influencing factors in elderly patients with Chronic Heart Failure[J]. Chin Nurs Manag, 2020, 20(3): 360-366. doi: 10.3969/j.issn.1672-1756.2020.03.010
    [11]
    胡寅田, 胡希文. 老年住院患者衰弱综合征与认知功能障碍和抑郁的相关性分析[J]. 中华全科医学, 2022, 20(11): 1913-1915, 1986. doi: 10.16766/j.cnki.issn.1674-4152.002734

    HU Y T, HU X W. Correlation analysis of frailty syndrome with cognitive dysfunction and depression among elderly inpatients[J]. Chinese Journal of General Practice, 2022, 20(11): 1913-1915, 1986. doi: 10.16766/j.cnki.issn.1674-4152.002734
    [12]
    马璐瑶, 林萍, 王琴, 等. 老年慢性心力衰竭患者肌少症的筛查及干预研究[J]. 中华全科医学, 2022, 20(3): 419-423. doi: 10.16766/j.cnki.issn.1674-4152.002367

    MA L Y, LIN P, WANG Q, et al. Screening and intervention of sarcopoenia in elderly patients with chronic heart failure[J]. Chinese Journal of General Practice, 2022, 20(3): 419-423. doi: 10.16766/j.cnki.issn.1674-4152.002367
    [13]
    MATSUE Y, KAMIYA K, SAITO H, et al. Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE-HF cohort study[J]. Eur J Heart Fail, 2020, 22(11): 2112-2119. doi: 10.1002/ejhf.1926
    [14]
    顾俊, 胡晓云, 李云玲, 等. 衰弱指数对老年心力衰竭患者预后的评估[J]. 中华老年心脑血管病杂志, 2021, 23(10): 1027-1029. doi: 10.3969/j.issn.1009-0126.2021.10.006

    GU J, HU X Y, LI Y L, et al. Evaluation of frailty index for prognosis of elderly patients with heart failure[J]. Chin J Geriatr Heart Brain Vessel Dis, 2021, 23(10): 1027-1029. doi: 10.3969/j.issn.1009-0126.2021.10.006
    [15]
    汪晨晨, 谢晖, 蔡维维. 社区老年人衰弱及其影响因素分析[J]. 中华全科医学, 2021, 19(4): 625-627, 683. doi: 10.16766/j.cnki.issn.1674-4152.001878

    WANG C C, XIE H, CAI W W. Analysis of the frailty of the elderly in community and its influencing factors[J]. Chinese Journal of General Practice, 2021, 19(4): 625-627, 683. doi: 10.16766/j.cnki.issn.1674-4152.001878
    [16]
    DENFELD Q E, WINTERS-STONE K, MUDD J O, et al. The prevalence of frailty in heart failure: a systematic review and meta-analysis[J]. Int J Cardiol, 2017, 236: 283-289. doi: 10.1016/j.ijcard.2017.01.153
    [17]
    LENA A, ANKER M S, SPRINGER J. Muscle wasting and sarcopenia in heart failure-the current state of science[J]. Int J Mol Sci, 2020, 21(18): 6549. doi: 10.3390/ijms21186549
    [18]
    高静媛, 俞卫娟, 张佳, 等. 老年心力衰竭住院患者发生衰弱的影响因素分析[J]. 中国循证心血管医学杂志, 2022, 14(5): 565-567, 574. doi: 10.3969/j.issn.1674-4055.2022.05.12

    GAO J Y, YU W J, ZHANG J, et al. Influence factors of asthenia in elderly hospitalized patients with heart failure[J]. Chin J Evid Based Cardiovasc Med, 2022, 14(5): 565-567, 574. doi: 10.3969/j.issn.1674-4055.2022.05.12
    [19]
    王巧稚, 吴海洋, 张璐, 等. 心血管病患者的衰弱发生情况及影响因素[J]. 中国健康教育, 2021, 37(2): 165-169. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJK202102018.htm

    WANG Q Z, WU H Y, ZHANG L, et al. Incidence and influencing factors of frailty in cardiovascular patients[J]. Chinese Journal of Health Education, 2021, 37(2): 165-169. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJK202102018.htm
    [20]
    汤莉莹, 李培, 白玉芝, 等. 老年心衰患者衰弱共病现状及短期预后的影响因素[J]. 中国急救医学, 2023, 43(6): 451-455. doi: 10.3969/j.issn.1002-1949.2023.06.005

    TANG L Y, LI P, BAI Y Z, et al. The status quo of weakness comorbidity and the influencing factors of short-term prognosis in elderly patients with heart failure[J]. Chin J Crit Care Med Jun, 2023, 43(6): 451-455. doi: 10.3969/j.issn.1002-1949.2023.06.005
    [21]
    孙丽星, 杨燕, 华皎, 等. 老年慢性心力衰竭患者呼吸道感染状况及其影响因素[J]. 中国老年学杂志, 2020, 40(15): 3144-3147. doi: 10.3969/j.issn.1005-9202.2020.15.003

    SUN L X, YANG Y, HUA J, et al. Status and influencing factors of respiratory tract infection in elderly patients with chronic heart failure[J]. Chinese Journal of Gerontology, 2020, 40(15): 3144-3147. doi: 10.3969/j.issn.1005-9202.2020.15.003
    [22]
    段菲, 闵春燕, 孙小卫, 等. 老年慢性阻塞性肺疾病患者发生衰弱的影响因素及其风险预测列线图模型构建[J]. 实用心脑肺血管病杂志, 2022, 30(9): 64-69. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXL202209014.htm

    DUAN F, MIN C Y, SUN X W, et al. Influential factors and establishment of risk prediction nomograph model of frailty in elderly patients with COPD[J]. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease, 2022, 30(9): 64-69. https://www.cnki.com.cn/Article/CJFDTOTAL-SYXL202209014.htm
    [23]
    WENNBERG A M V, ST LOUIS E K. Interconnectedness among frailty, sleep, and cognition: recent findings and clinical implications[J]. Int Psychogeriatr, 2019, 31(6): 763-766. doi: 10.1017/S1041610219000462
    [24]
    吕秋, 邱清勇, 杜兰雪, 等. 老年射血分数保留型心衰合并衰弱的临床特征及NT-proBNP超声心动图参数变化的临床意义[J]. 河北医学, 2023, 29(9): 1479-1483. doi: 10.3969/j.issn.1006-6233.2023.09.013

    LYU Q, QIU Q Y, DU L X, et al. Clinical characteristics and clinical significance of changes in NT-proBNP and echocardiographic parameters in elderly with ejection fraction preserved heart failure combined with debility[J]. Hebei Med, 2023, 29(9): 1479-1483. doi: 10.3969/j.issn.1006-6233.2023.09.013
    [25]
    裴莹莹, 王秀红, 汪俊华, 等. 社区老年慢性疼痛患者衰弱发生现状及其与社会支持和自我管理行为的关系[J]. 贵州医科大学学报, 2023, 48(6): 710-716. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYB202306014.htm

    PEI Y Y, WANG X H, WANG J H, et al. Status of debilitation in elderly patients with chronic pain in community and its relationship with social support and self-management behavior[J]. Journal of Guizhou Medical University, 2023, 48(6): 710-716. https://www.cnki.com.cn/Article/CJFDTOTAL-GYYB202306014.htm
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (262) PDF downloads(9) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return