Volume 22 Issue 9
Sep.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(9): 1546-1549
YANG Liqing, ZHAN Hong. Impact of pelvic floor therapeutic instrument assisted with traditional Chinese medicine on inflammation and hormone levels in patients with pelvic inflammatory disease[J]. Chinese Journal of General Practice, 2024, 22(9): 1546-1549. doi: 10.16766/j.cnki.issn.1674-4152.003679
Citation: YANG Liqing, ZHAN Hong. Impact of pelvic floor therapeutic instrument assisted with traditional Chinese medicine on inflammation and hormone levels in patients with pelvic inflammatory disease[J]. Chinese Journal of General Practice, 2024, 22(9): 1546-1549. doi: 10.16766/j.cnki.issn.1674-4152.003679
shu

Impact of pelvic floor therapeutic instrument assisted with traditional Chinese medicine on inflammation and hormone levels in patients with pelvic inflammatory disease

doi: 10.16766/j.cnki.issn.1674-4152.003679
  • 1.

    Department of Obstetrics and Gynecology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang 310009, China

Funds:

 LQ20H040006

 WJCY319

  • Received Date: 2024-01-23
    Abstract
  •   Objective  To analyze the effects of pelvic floor therapeutic instrument assisted with traditional Chinese medicine in vagina on inflammation and hormone level of patients with chronic pelvic inflammatory disease (CPID), so as to provide more sufficient theoretical basis for the treatment of CPID.  Methods  Ninety patients with CPID admitted to Hangzhou Third People's Hospital from March 2020 to October 2023 were divided into two groups according to different treatment methods: the enema group with traditional Chinese medicine and the vaginal treatment group, with 45 patients in each group. Both groups were treated with pelvic floor therapeutic instrument, with the enema group also receiving traditional Chinese medicine via enema and the intravaginal group receiving it vaginally. The clinical efficacy, inflammation levels, hormone levels, and incidence of adverse reactions were compared between the two groups.  Results  After treatment, the total effective rate in the vaginal treatment group (91.11%, 41/45) was higher than that in the enema group (75.56%, 34/45, P < 0.05). Tumor necrosis factor-α and CRP levels in the vaginal treatment group were lower than those in the traditional Chinese medicine enema group (P < 0.05), while the levels of interleukin-2 and interleukin-4 were higher (P < 0.05). Follicle-stimulating hormone levels in the vaginal treatment group was lower than that in the traditional Chinese medicine enema group, and estradiol was higher (P < 0.05). Additionally, proteasome inhibitor levels of ovarian artery and uterine artery in the vaginal treatment group were higher than that in the traditional Chinese medicine enema group, and resistance index was lower compared to the enema group.  Conclusion  Pelvic floor therapeutic instrument assisted with vaginal Chinese medicine can reduce the level of inflammatory factors, regulate hormones levels, improve the level of hemodynamics, and enhance the clinical efficacy in the treatment of CPID.

     

    • FullText(HTML)
  • loading
    • References(22)
  • [1]
    CURRY A, WILLUAMS T, PENNY M L. Pelvic inflammatory disease: diagnosis, management, and prevention[J]. Am Fam Physician, 2019, 100(6): 357-364.
    [2]
    曹静. 整体护理与盆腔炎治疗仪对慢性盆腔炎患者健康行为疼痛程度和疾病复发的影响[J]. 山西医药杂志, 2021, 50(2): 312-315.

    CAO J. The effect of holistic nursing and pelvic inflammatory disease treatment instrument on the pain degree of health behavior and disease recurrence of patients with chronic pelvic inflammatory disease[J]. Shanxi Medical Journal, 2021, 50(2): 312-315.
    [3]
    李晓娟, 邱育红. 红藤汤保留灌肠对慢性盆腔炎患者疗效及对免疫-炎症因子的调节作用[J]. 中医药学报, 2020, 48(10): 26-31.

    LI X J, QIU Y H. Effect of Retention Enema of Hongteng Decoction on CPID and Its Regulation on Immune Inflammatory Factors[J]. Acta Chinese Medicine and Pharmacology, 2020, 48(10): 26-31.
    [4]
    HORNE A W, MISSMER S A. Pathophysiology, diagnosis, and management of endometriosis[J]. BMJ, 2022, 379: e070750. DOI: 10.1136/bmj-2022-070750.
    [5]
    赵红玉, 熊枫, 刘新敏. 康妇消炎栓联合抗生素治疗慢性盆腔炎的系统评价和Meta分析[J]. 世界中医药, 2022, 17(22): 3180-3188, 3199. doi: 10.3969/j.issn.1673-7202.2022.22.010

    ZHAO H Y, XIONG F, LIU X M. Systematic Review and Meta-analysis of Kangfu Xiaoyan Suppository Combined with Antibiotics in the Treatment of Chronic Pelvic Inflammatory Disease[J]. World Chinese Medicine, 2022, 17(22): 3180-3188, 3199. doi: 10.3969/j.issn.1673-7202.2022.22.010
    [6]
    中华医学会妇产科学分会感染性疾病协作组. 盆腔炎症性疾病诊治规范(2019修订版)[J]. 中华妇产科杂志, 2019, 54(7): 433-437.

    Cooperative Group of Infectious Diseases of Obstetrics and Gynecology Branch of Chinese Medical Association. Guideline of pelvic inflammatory disease (2019 revised edition)[J]. Chinese Journal of Obstetrics and Gynecology, 2019, 54(7): 433-437.
    [7]
    中华中医药学会. 中医妇科常见病诊疗指南[M]. 北京: 中国中医药出版社, 2012.

    Chinese Society of Traditional Chinese Medicine. Guidelines for diagnosis and treatment of common gynecological diseases in traditional Chinese medicine[M]. Beijing: China Press of Chinese Medicine, 2012.
    [8]
    郑筱萸. 中药新药临床研究指导原则(试行)[S]. 北京: 中国医药科技出版社, 2002: 243-253.

    ZHENG X Y. Guiding Principles for Clinical Research of New Chinese Medicine (Trial)[S]. Beijing: China Medical Science Press, 2002: 243-253.
    [9]
    陈湘宜, 胡欣欣. 当归芍药散加味治疗盆腔炎患者的临床效果[J]. 中华全科医学, 2020, 18(2): 255-257, 261. doi: 10.16766/j.cnki.issn.1674-4152.001219

    CHEN X Y, HU X X. Clinical effect of Danggui Shaoyao powder in the treatment of pelvic inflammation patients[J]. Chinese Journal of General Practice, 2020, 18(2): 255-257, 261. doi: 10.16766/j.cnki.issn.1674-4152.001219
    [10]
    KLIMASZYK K, SVARRE NIELSEN H, WENDER-OZEGOWSKA E, et al. Chronic endometritis -is it time to clarify diagnostic criteria[J]. Ginekol Pol, 2023, 94(2): 152-157. doi: 10.5603/GP.a2022.0147
    [11]
    DARVOLLE T. Pelvic inflammatory disease due to neisseria gonorrhoeae and chlamydia trachomatis: immune evasion mechanisms and pathogenic disease pathways[J]. J Infect Dis, 2021, 224(12): S39-S46.
    [12]
    PAPANIKOLAOU D T, LAMPROPOULOU S, GIABBITSAS K, et al. Pelvic floor muscle training: novel versus traditional remote rehabilitation methods. A systematic review and meta-analysis on their effectiveness for women with urinary incontinence[J]. Neurourol Urodyn, 2023, 42(4): 856-874.
    [13]
    袁爱玲, 戴丽萍. 盆底康复治疗仪联合盆底肌肉锻炼治疗女性盆底功能障碍的疗效观察[J]. 当代临床医刊, 2023, 36(6): 38-39.

    YUAN A L, DAI L P. Observation on the curative effect of pelvic floor rehabilitation therapy combined with pelvic floor muscle exercise on female pelvic floor dysfunction[J]. Journal of Contemporary Clinical Medicine, 2023, 36(6): 38-39.
    [14]
    李海晖, 金芳和. 盆底康复治疗仪用于慢性盆腔疼痛的疗效研究[J]. 现代仪器与医疗, 2022, 28(1): 76-79.

    LI H H, JIN F H. Study on the comprehensive effect of pelvic floor rehabilitation therapy instrument in gynecological treatment of chronic pelvic pain[J]. Modern Instruments & Medical Treatment, 2022, 28(1): 76-79.
    [15]
    周敏, 厉霞玲, 刘胜齐, 等. 红藤汤加减方结肠透析治疗对湿热瘀结证盆腔炎性包块疗效观察[J]. 四川中医, 2021, 39(11): 180-183.

    ZHOU M, LI X L, LIU S Q, et al. Observation on the therapeutic effect of Hongteng Decoction on pelvic inflammatory mass with damp-heat and blood stasis syndrome[J]. Journal of Sichuan of Traditional Chinese Medicine, 2021, 39(11): 180-183.
    [16]
    韦柳溢, 郝二伟, 侯小涛, 等. 薏苡附子败酱散的临床应用与药理作用研究进展[J]. 中国中药杂志, 2023, 48(18): 4893-4901.

    WEI L Y, HAO E W, HOU X T, et al. Research progress in clinical application and pharmacological effect of Yiyi Fuzi Baijiang Powder[J]. China Journal of Chinese Materia Medica, 2023, 48(18): 4893-4901.
    [17]
    赵光耀, 赵坤, 蒋文雯, 等. 基于网络药理学对蒲公英抑制α-葡萄糖苷酶活性成分及作用机制的研究[J]. 天然产物研究与开发, 2020, 32(3): 403-413, 440.

    ZHAO G Y, ZHAO K, JIANG W W, et al. Study on active components and mechanism of inhibition of α- glucosidase by Taraxacum mongolicum based on network pharmacology[J]. Natural Product Research and Development, 2020, 32(3): 403-413, 440.
    [18]
    胡娈倩, 陈玉琪, 马昕, 等. 红藤-败酱草抗炎作用物质基础研究进展[J]. 中成药, 2022, 44(4): 1219-1223.

    HU L Q, CHEN Y Q, MA X, et al. Research progress on anti-inflammatory substance of Sargentodoxa-Patrinia[J]. Chinese Traditional Patent Medicine, 2022, 44(4): 1219-1223.
    [19]
    刘丽华, 曹泽伟. 红藤汤对小鼠溃疡性结肠炎的保护作用及机制探究[J]. 中国中西医结合外科杂志, 2020, 26(2): 232-236.

    LIY L H, CAO Z W. Protective Effect and Mechanism of Hongteng Decoction on Mice with DSS-induced Ulcerative Colitis[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2020, 26(2): 232-236.
    [20]
    张婷, 宋厚盼, 林也, 等. 黄连解毒汤之"清热解毒"药效与作用机制研究进展[J]. 中华中医药学刊, 2020, 38(11): 135-139.

    ZHANG T, SONG H P, LIN Y, et al. Research Advances on Pharmacological Effects and Mechanisms Underlying Heat-Clearing and Detoxifying Effect of Huanglian Jiedu Decoction[J]. Chinese Archives of Traditional Chinese Medicine, 2020, 38(11): 135-139.
    [21]
    叶金力, 梁瑞丽, 邢天伶, 等. 清热化湿逐瘀汤联合红藤方保留灌肠治疗慢性盆腔炎湿热瘀结证患者的疗效观察[J]. 世界中西医结合杂志, 2023, 18(2): 352-356, 362.

    YE J L, LIANG R L, XING T L, et al. Clinical Observation of Qingre Huashi Zhuyu Decoction Combined with Hongteng Formula Retention Enema in The Treatment of Chronic Pelvic Inflammatory Disease with Dampness-heat Stasis Syndrome[J]. World Journal of Integrated Traditional and Western Medicine, 2023, 18(2): 352-356, 362.
    [22]
    COOK M T, BROWN M B. Polymeric gels for intravaginal drug delivery[J]. J Control Release, 2018, 28(270): 145-157.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(5)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (21) PDF downloads(3) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return