Volume 22 Issue 10
Oct.  2024
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(10): 1645-1647
LÜ Huijie, FENG Qian, LÜ Wen, XIE Lu, ZHANG Hongchen, LI Shudan. Evaluation of the feasibility and safety of capsule endoscopy in newly diagnosed Crohn's patients[J]. Chinese Journal of General Practice, 2024, 22(10): 1645-1647. doi: 10.16766/j.cnki.issn.1674-4152.003702
Citation: LÜ Huijie, FENG Qian, LÜ Wen, XIE Lu, ZHANG Hongchen, LI Shudan. Evaluation of the feasibility and safety of capsule endoscopy in newly diagnosed Crohn's patients[J]. Chinese Journal of General Practice, 2024, 22(10): 1645-1647. doi: 10.16766/j.cnki.issn.1674-4152.003702
shu

Evaluation of the feasibility and safety of capsule endoscopy in newly diagnosed Crohn's patients

doi: 10.16766/j.cnki.issn.1674-4152.003702
  • 1.

    Department of Gastroenterology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang 310003, China

Funds:

 2021KY857

 2022WJC099

 A20220596

  • Received Date: 2024-02-25
    Abstract
  •   Objective  To explore the feasibility and safety of capsule endoscopy as a diagnostic tool in newly diagnosed Crohn's patients.  Methods  From August 2019 to August 2023, 60 patients with Crohn's disease newly diagnosed at the First People's Hospital Affiliated to West Lake University in Hangzhou were selected as the research subjects, and they all underwent capsule endoscopy. Statistics were made on the clinical characteristics of the subjects and the observation results of capsule endoscopy. The completion rate of this examination and the incidence of adverse clinical events reflect the feasibility and safety of its clinical application. Simultaneously analyze the lesion characteristics and inflence infactor of positive capsule endoscopy result, and effect of patient age on capsule endoscopy result.  Results  The mean age of the 60 patients was (37.0±14.2) years, and 35.0% (21/60) of the patients were diagnosed with Crohn's disease before CE examination. 21.7% of the patients were accompanied by perianal lesions and parenteral complications, with abdominal pain and diarrhea as the main clinical symptoms. The positive rate of capsule endoscopy was 80.0% (48/60), and the mean passage time of the small intestine was (258.5±128.2) min. 59 patients successfully completed the examination, and 1 patient had capsule retention (retention rate 1.7%, 1/60). CE examination found that the most common lesions of this disease were erosion, ulcer, and stenosis, and 72.9% (35/48) of patients in the lower small intestine lesions than the upper segment. The proportion of bleeding and upper small intestine lesions in young patients (≤30 years old) was higher than that in patients >30 years old (P < 0.05). CRP is a significant factor affecting the positive results of capsule endoscopy (P < 0.05).  Conclusion  Capsule endoscopy is feasible and safe in newly diagnosed patients with Crohn's disease, especially in young patients with lesions in the upper small intestine. CRP is a related factor affecting the positive results of capsule endoscopy.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    丘栋豪, 欧阳春晖, 汪春莲, 等. 胶囊内镜对小肠克罗恩病诊断及疾病活动评估的价值[J]. 中华炎性肠病杂志, 2022, 6(4): 358-362.

    QIU D H, OUYANG C H, WANG C L, et al. Value of capsule endoscopy for diagnosis and assessment of disease activity in small bowel Crohn's disease[J]. Chinese Journal of Inflammatory Bowel Diseases, 2022, 6(4): 358-362.
    [2]
    刘曼, 柯希权, 王启之, 等. 不同类型胶囊内镜对消化道疾病诊断价值的探讨[J]. 中华全科医学, 2021, 19(4): 589-592. doi: 10.16766/j.cnki.issn.1674-4152.001868

    LIU M, KE X Q, WANG Q Z, et al. Diagnostic value of different types of capsule endoscopy in digestive tract diseases[J]. Chinese Journal of General Practice, 2021, 19(4): 589-592. doi: 10.16766/j.cnki.issn.1674-4152.001868
    [3]
    PENNAZIO M, RONDONOTTI E, DESPOTT E J, et al. Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Guideline-Update 2022[J]. Endoscopy, 2023, 55(1): 58-95. doi: 10.1055/a-1973-3796
    [4]
    CHETCUTI ZAMMIT S, SIDHU R. Capsule endoscopy-Recent developments and future directions[J]. Expert Rev Gastroenterol Hepatol, 2021, 15(2): 127-137. doi: 10.1080/17474124.2021.1840351
    [5]
    陈雨霏, 王启之, 柯希权, 等. 磁控胶囊胃镜在上消化道疾病筛查中的应用[J]. 中华全科医学, 2019, 17(4): 543-546, 600. doi: 10.16766/j.cnki.issn.1674-4152.000729

    CHEN Y F, WANG Q Z, KE X Q, et al. Application of magnetically controlled capsule endoscopy in upper gastrointestinal tract disease screening[J]. Chinese Journal of General Practice, 2019, 17(4): 543-546, 600. doi: 10.16766/j.cnki.issn.1674-4152.000729
    [6]
    陈轩馥, 杨红. 胶囊内镜在小肠克罗恩病诊断及病情评估中的应用价值[J]. 胃肠病学和肝病学杂志, 2019, 28(6): 697-700.

    CHEN X F, YANG H. Application value of capsule endoscopy in diagnosis and evaluation of small blwel Crohn's disease[J]. Chin J of Gastroenterol and Hepatol, 2019, 28(6): 697-700.
    [7]
    LIMPIAS KAMIYA K J L, HOSOE N, HAYASHI Y, et al. Video capsule endoscopy in inflammatory bowel disease[J]. DEN Open, 2021, 2(1): e26. DOI: 10.1002/deo2.26.
    [8]
    LAHAT A, VEISMAN I. Capsule endoscopy in Crohn's disease-from a relative contraindication to habitual monitoring tool[J]. Diagnostics(Basel), 2021, 11(10): 1737.
    [9]
    吴铖. 胶囊内镜与小肠CT成像在小肠克罗恩病诊断中的应用价值[J]. 影像研究与医学应用, 2020, 4(18): 96-97.

    WU C. Capsule Endoscopy and CT Enterography in Diagnosis of Small Intestinal Crohn's Disease[J]. Journal of Imaging Research and Medical Applications, 2020, 4(18): 96-97.
    [10]
    许文敏, 冯志强. 胶囊内镜滞留的研究进展[J]. 胃肠病学和肝病学杂志, 2020, 29(4): 469-473.

    XU W M, FENG Z Q. Advances in research on capsule endoscopy retention[J]. Chin J of Gastroenterol and Hepatol, 2020, 29(4): 469-473.
    [11]
    ELOSUA A, RULLAN M, RUBIO S, et al. Does capsule endoscopy impact clinical management in established Crohn's disease?[J]. Dig Liver Dis, 2022, 54(1): 118-124. doi: 10.1016/j.dld.2021.08.014
    [12]
    赵凯, 杨云锋, 王俊平. 胶囊内镜在小肠疾病诊断中的价值[J]. 中华内科杂志, 2020, 59(2): 124-128.

    ZHAO K, YANG Y F, WANG J P. Clinical value of capsule endoscopy in small intestinal diseases[J]. Chinese Journal of Internal Medicine, 2020, 59(2): 124-128.
    [13]
    PAPALIA I, TJANDRA D, QUAH S, et al. Colon capsule endoscopy in the assessment of mucosal healing in Crohn's disease[J]. Inflamm Bowel Dis, 2021, 27(2): S25-S32.
    [14]
    张婷, 朱佳慧, 廖专. 小肠胶囊内镜的临床应用价值[J]. 中国实用内科杂志, 2022, 42(1): 8-12.

    ZHANG T, ZHU J H, LIAO Z. Clinical application value of small intestine capsule endoscopy[J]. Chinese Journal of Practical Internal Medicine, 2022, 42(1): 8-12.
    [15]
    UNGAR B, ELIAKIM R. Does pan-enteric capsule endoscopy obviate magnetic resonance entero-colonography in suspected Crohn's disease?[J]. United European Gastroenterol J, 2022, 10(9): 917-918.
    [16]
    OMORI T, MATSUMOTO T, HARA T, et al. A novel capsule endoscopic score for Crohn's disease[J]. Crohns Colitis, 2020, 2(2): otaa040. DOI: 10.1093/crocol/otaa040.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (44) PDF downloads(2) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return