Volume 22 Issue 10
Oct.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(10): 1781-1786
LIANG Bo, YUAN Ding, WANG Jianye, ZHOU Shaolong, LIU Rongjun, WANG Xinjun. Global research trends of pyroptosis in tumor based on bibliometrics and visualization analysis[J]. Chinese Journal of General Practice, 2024, 22(10): 1781-1786. doi: 10.16766/j.cnki.issn.1674-4152.003733
Citation: LIANG Bo, YUAN Ding, WANG Jianye, ZHOU Shaolong, LIU Rongjun, WANG Xinjun. Global research trends of pyroptosis in tumor based on bibliometrics and visualization analysis[J]. Chinese Journal of General Practice, 2024, 22(10): 1781-1786. doi: 10.16766/j.cnki.issn.1674-4152.003733
shu

Global research trends of pyroptosis in tumor based on bibliometrics and visualization analysis

doi: 10.16766/j.cnki.issn.1674-4152.003733
  • 1.

    Department of Neurosurgery, the Fifth Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan 450052, China

Funds:

 81972361

 LHGJ20200477

 222102310039

  • Received Date: 2024-02-01
    Available Online: 2024-12-28
    Abstract
  •   Objective  Through bibliometric analysis, comprehensively review and analyze research in the field of tumor pyroptosis, revealing the global distribution of research hotspots in this area. Based on this, speculate on the future development directions and trends in this field.  Methods  Retrieve english-language literature on tumor pyroptosis from the Web of Science database from January 1, 2007 to December 31, 2023. Use VOSviewer and CiteSpace for multi-dimensional analysis.  Results  A total of 2 709 articles were included in the analysis. The volume of publications in the field showed explosive growth after 2019. The top three countries in terms of publication volume were China, the United States and Germany. Among the top 10 most productive authors, 6 were from China. In addition, three of the top five publications came from Frontiers journals. The keyword analysis showed that before 2020, the focus was mainly on mechanisms and pathways such as "NLRP3 inflammasome" "autophagy" "NF-Kappa-B" "pathways" and "proliferation". However, in recent years, keywords such as "tumor microenvironment" "prognosis" "treatment" "survival" "cisplatin" and "immunotherapy" have begun to appear frequently.  Conclusion  Tumor pyroptosis has become a global research hotspot, and its crucial role in both anticancer and cancer-promoting processes is gradually attracting the attention of researchers. With the deepening exploration of the mechanisms of tumor pyroptosis, we have reason to believe that it will have a profound impact on the future of tumor treatment.

     

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