Effect of <i>Buyang Huanwu</i> Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function

WANG Guojun; LEI Haijun; YANG Li; JING Rong; GAO Li; FU Chun'ai

doi:10.16766/j.cnki.issn.1674-4152.003769

Volume 22 Issue 11

Nov. 2024

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WANG Guojun, LEI Haijun, YANG Li, JING Rong, GAO Li, FU Chun'ai. Effect of Buyang Huanwu Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function[J]. Chinese Journal of General Practice, 2024, 22(11): 1938-1941. doi: 10.16766/j.cnki.issn.1674-4152.003769

Citation:

WANG Guojun, LEI Haijun, YANG Li, JING Rong, GAO Li, FU Chun'ai. Effect of Buyang Huanwu Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function[J]. Chinese Journal of General Practice, 2024, 22(11): 1938-1941. doi: 10.16766/j.cnki.issn.1674-4152.003769

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Effect of Buyang Huanwu Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function

doi: 10.16766/j.cnki.issn.1674-4152.003769

WANG Guojun^{1
,
,}
, LEI Haijun¹
, YANG Li¹
, JING Rong¹
, GAO Li²
, FU Chun'ai²

1.
Rehabilitation Medicine Department of Cardiovascular and Cerebrovascular Disease Hospital of Yan' an University Affiliated Hospital, Yan' an, Shaanxi 716000, China

Funds:

2022SLSFGG-032

2022PT-34

2021B008

Received Date: 2023-11-29
Available Online: 2024-12-31

Abstract

Abstract

Objective To explore the effects of combing the classic formula Buyang Huanwu Decoction with personalized cognitive training on cognitive dysfunction and neurological function after stroke. Methods A total of 98 post stroke cognitive impairment (PSCI) patients were selected form those admitted to the Rehabilitation Medicine Department of Yan' an University Affiliated Hospital for treatment between August 2022 and August 2023. The patients were randomly divided into a control group and a treatment group using a random number table method, with 49 patients in each group. The control group received comprehensive rehabilitation treatment after stroke, while the treatment group received individualized cognitive training and traditional Chinese medicine syndrome differentiation on the basis of the control group' s treatment. The treatment group also used Buyang Huanwu Decoction as the basis for modified syndrome differentiation. Compare the scores of Montreal cognitive assessment (MoCA), activities of daily living (ADL), National Institutes of Health stroke scale (NIHSS), mini mental state examination (MMSE), and nonverbal neuropsychiatric assessment (NLCA) between two groups of patients before and after treatment. Observe the incidence of adverse drug reactions in both patient groups during the treatment process. Results After treatment, the total effective rate of the treatment group was 95.92% (47/49), which was higher than that of the control group [81.63% (40/49), χ²=5.017, P=0.025]. Following treatment, the MoCA score, ADL score, MMSE score, and NLCA score of the treatment group were significantly higher than those of the control group, while the NIHSS score was lower than that of the control group (P < 0.05). The incidence of adverse reactions in both groups was 4.08% (2/49). Conclusion The combination of Buyang Huanwu Decoction and personalized cognitive training can significantly enhance the cognitive function effect of PSCI patients, leading to a substantial improvement in their quality of life while ensuring high safety. Thus, it can be considered as a favorable treatment option for PSCI patients.
- Post stroke cognitive impairment,
- Buyang Huanwu Decoction,
- TCM treatment,
- Individualized cognitive training

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References(17)

References

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Effect of Buyang Huanwu Decoction combined with individual cognitive training on post-stroke cognitive dysfunction and neurological function

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