Volume 22 Issue 12
Dec.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(12): 2112-2115
WANG Yu, YAN Zhihui, YUAN Pengfei, HE Manman. The efects of fire acupuncture combined with Zishen Qinggan Decoction on recovery progress, body inflammation and risk of PHN in patients with acute herpes zoster[J]. Chinese Journal of General Practice, 2024, 22(12): 2112-2115. doi: 10.16766/j.cnki.issn.1674-4152.003810
Citation: WANG Yu, YAN Zhihui, YUAN Pengfei, HE Manman. The efects of fire acupuncture combined with Zishen Qinggan Decoction on recovery progress, body inflammation and risk of PHN in patients with acute herpes zoster[J]. Chinese Journal of General Practice, 2024, 22(12): 2112-2115. doi: 10.16766/j.cnki.issn.1674-4152.003810
shu

The efects of fire acupuncture combined with Zishen Qinggan Decoction on recovery progress, body inflammation and risk of PHN in patients with acute herpes zoster

doi: 10.16766/j.cnki.issn.1674-4152.003810
  • 1.

    Department of Acupuncture and Moxibustion, Chengde Hospital of Traditional Chinese Medicine, Chengde, Hebei 067000, China

Funds:

 2021270

 202301A026

  • Received Date: 2024-05-11
    Available Online: 2025-01-20
    Abstract
  •   Objective   To observe the therapeutic effect of fire acupuncture combined with Zishen Qinggan Decoction on acute herpes zoster and the occurrence of postherpetic neuralgia (PHN).   Methods   From January 2022 to September 2023, 100 patients with acute herpes zoster in the moxibustion Department of Chengde Hospital of Traditional Chinese Medicine were divided into the observation group (n=50, fire acupuncture combined with Zishen Qinggan Decoction) and the control group (n=50, fire acupuncture) by random number table method. The therapeutic effect, traditional Chinese medicine (TCM) syndrome scores, recovery progress, inflammatory indicators [interleukin (IL-2), IL-8, IL-10], and PHN risk were compared.   Results   The total effective rate in the observation group was higher (88.00% vs. 72.00%, P < 0.05), and the scores of TCM syndrome were lower (P < 0.05). Analgesic time [(2.95±0.46) d vs. (3.57±1.02) d], herpes stopping time [(3.77±0.93) d vs. (4.69±1.47) d], and crusting time [(7.80±1.18) d vs. (8.36±0.61) d] in the observation group was shorter (P < 0.05). After treatment, the serum IL-2 concentration in the observation group was higher (P < 0.05), and the serum IL-8 and IL-10 concentrations were lower (P < 0.05). No adverse reactions occurred in both groups. The incidence of PHN at 1 month (12.00% vs. 28.00%, χ2=4.000, P=0.046) and 2 months (6.00% vs. 20.00%, χ2=4.332, P=0.037) in the observation group was lower than that in the control group.   Conclusion   Fire acupuncture combined with Zishen Qinggan Decoction can significantly improve the treatment effect of patients with acute herpes zoster, relieve symptoms, and reduce the incidence of PHN.

     

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