Volume 22 Issue 12
Dec.  2024
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Article Navigation >  Chinese Journal of General Practice  > 2024  >  22(12): 2158-2161
HU Fei, YANG Hua, YANG Ting, LI Lu. Analysis of risk factors and nursing strategies for sleep disorders in lung cancer chemotherapy patients based on decision tree model[J]. Chinese Journal of General Practice, 2024, 22(12): 2158-2161. doi: 10.16766/j.cnki.issn.1674-4152.003820
Citation: HU Fei, YANG Hua, YANG Ting, LI Lu. Analysis of risk factors and nursing strategies for sleep disorders in lung cancer chemotherapy patients based on decision tree model[J]. Chinese Journal of General Practice, 2024, 22(12): 2158-2161. doi: 10.16766/j.cnki.issn.1674-4152.003820
shu

Analysis of risk factors and nursing strategies for sleep disorders in lung cancer chemotherapy patients based on decision tree model

doi: 10.16766/j.cnki.issn.1674-4152.003820

  • Cancer Medical Center of the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330001, China

Funds:

 GJJ2200122

  • Received Date: 2024-05-18
    Available Online: 2025-01-20
    Abstract
  •   Objective  To analyze the influencing factors of sleep disorders in lung cancer chemotherapy patients and develop nursing strategies to reduce the risk of sleep disorders in lung cancer chemotherapy patients.  Methods  A total of 110 lung cancer patients admitted to the First Affiliated Hospital of Nanchang University from January 2023 to December 2023 were selected as the research subjects. Patients were divided into a sleep disorder group (n=44) and a non-sleep disorder group (n=66) based on the Athens insomnia scale (AIS) score. Baseline data and laboratory indicators were compared between the two groups; Binary logistic regression was used to analyze the influencing factors of sleep disorders in lung cancer chemotherapy patients, build a decision tree model, and draw receiver operating characteristic curves (ROC) to verify the predictive efficiency of the decision tree model.  Results  The incidence of sleep disorders in lung cancer chemotherapy patients [40.00% (44/110)]; The chemotherapy cycle, visual analog scale (VAS) score, interleukin-6 (IL-6), tumor necrosis factor -α (TNF -α), and C-reactive protein (CRP) in the sleep disorder group were higher than those in the non-sleep disorder group. The proportion of stage Ⅲ-Ⅳ and the use of paclitaxel+platinum chemotherapy regimen was higher in the sleep disorder group than in the non-sleep disorder group (P<0.05); According to binary logistic regression analysis, stages Ⅲ-Ⅳ, paclitaxel+platinum chemotherapy regimen, chemotherapy cycle, VAS score, and IL-6 were the influencing factors of sleep disorders in lung cancer chemotherapy patients (OR>1, P<0.05). A decision tree model was generated by incorporating these factors, and three explanatory variables including VAS score, IL-6, and TNM staging were screened out. VAS score was the most important root node variable and predictor. The AUC of the decision tree prediction model was 0.915, P<0.001, indicating a high predictive value.  Conclusion  The decision tree model constructed by TNM staging, chemotherapy regimen, chemotherapy cycle, VAS score, and IL-6 has a high predictive value for sleep disorders in lung cancer chemotherapy patients.

     

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    • References(20)
  • [1]
    SUNG H, FERLAY J, SIEGEL R L, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. doi: 10.3322/caac.21660
    [2]
    CHAFT J E, RIMNER A, WEDER W, et al. Evolution of systemic therapy for stages Ⅰ-Ⅲ non-metastatic non-small-cell lung cancer[J]. Nat Rev Clin Oncol, 2021, 18(9): 547-557. doi: 10.1038/s41571-021-00501-4
    [3]
    BUTTNER-TELEAGA A, KIM Y T, OSEL T, et al. Sleep disorders in cancer-a systematic review[J]. Int J Environ Res Public Health, 2021, 18(21): 11696. DOI: 10.3390/ijerph182111696.
    [4]
    中华医学会, 中华医学会肿瘤学分会, 中华医学会杂志社. 中华医学会肺癌临床诊疗指南(2019版)[J]. 中华肿瘤杂志, 2020, 42(4): 257-287.

    Chinese Medical Association, Oncology Society of Chinese Medical Association, Chinese Medical Association Publishing House. Chinese Medical Association guidelines for clinical diagnosis and treatment of lung cancer (2019 edition)[J]. Chinese Journal of Oncology, 2020, 42(4): 257-287.
    [5]
    中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2020年版)[J]. 中华糖尿病杂志, 2021, 13(4): 315-409.

    Chinese Diabetes Society. Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition)[J]. Chinese Journal of Diabetes, 2021, 13(4): 315-409.
    [6]
    中华医学会, 中华医学杂志社, 中华医学会全科医学分会, 等. 高血压基层诊疗指南(2019年)[J]. 中华全科医师杂志, 2019, 18(4): 301-313.

    Chinese Medical Association, Chinese Medical Journal, General Practice Branch of Chinese Medical Association, et al. Guideline for primary care of hypertension (2019)[J]. Chinese Journal of General Practitioners, 2019, 18(4): 301-313.
    [7]
    ANNUNZIATA M A, MUZZATTI B, MELLA S, et al. The revised piper fatigue scale (PFS-R) for italian cancer patients: a validation study[J]. Tumori, 2010, 96(2): 276-281. doi: 10.1177/030089161009600215
    [8]
    SOLDATOS C R, DIKEOS D G, PAPARRIGOPOULOS T J. Athens insomnia scale: validation of an instrument based on ICD-10 criteria[J]. J Psychosom Res, 2000, 48(6): 555-560. doi: 10.1016/S0022-3999(00)00095-7
    [9]
    谭磊, 田小华, 钟欣怡, 等. 肺癌初治患者睡眠障碍调查及与生活质量和睡眠卫生意识的关系研究[J]. 现代生物医学进展, 2021, 21(14): 2693-2697, 2716.

    TAN L, TIAN X H, ZHONG X Y, et al. Investigation of sleep disorder in patients with primary treatment of lung cancer and its relationship with quality of life and sleep hygiene awareness[J]. Progress in Modern Biomedicine, 2021, 21(14): 2693-2697, 2716.
    [10]
    张炎改, 余春华, 李俊英. 肺癌初治患者睡眠障碍影响因素分析及与生活质量的相关性研究[J]. 四川医学, 2020, 41(3): 252-256.

    ZHANG Y G, YU C H, LI J Y. Analysis of influencing factors of sleep disorders in newly treated patients with lung cancer and its correlation with quality of life[J]. Sichuan Medical Journal, 2020, 41(3): 252-256.
    [11]
    王瑞. 肿瘤住院患者睡眠障碍的影响因素分析[J]. 国际精神病学杂志, 2020, 47(4): 815-817, 838.

    WANG R. Study on the influencing factors of sleep disturbance in inpatients with tumor[J]. Journal of International Psychiatry, 2020, 47(4): 815-817, 838.
    [12]
    胡光玲, 乔昕悦, 张林虹, 等. 心房颤动患者睡眠质量与生活质量的相关性分析[J]. 中华全科医学, 2021, 19(1): 24-26, 41. doi: 10.16766/j.cnki.issn.1674-4152.001720

    HU G L, QIAO X Y, ZHANG L H, et al. Correlation analysis of sleep quality and life quality in patients with atrial fibrillation[J]. Chinese Journal of General Practice, 2021, 19(1): 24-26, 41. doi: 10.16766/j.cnki.issn.1674-4152.001720
    [13]
    张艳, 李云霞, 刘安萍. 延续性护理联合呼吸锻炼对肺癌患者出院后呼吸功能和自我效能及睡眠障碍的影响[J]. 中国肿瘤临床与康复, 2020, 27(1): 125-128.

    ZHANG Y, LI Y X, LIU A P. Effect of continuous nursing combined with breathing exercise on respiratory system, self-efficacy and sleep disorders in patients with prehospital lung cancer[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2020, 27(1): 125-128.
    [14]
    KATO T, OKAWA G, TANAKA K F, et al. Dexamethasone induces sleep disturbance in a dose-dependent manner in mice[J]. PLoS One, 2023, 18(12): e0296028. DOI: 10.1371/journal.pone.0296028.
    [15]
    DE FFEIJTER M, TIEMENSMA J, IKRAM M A, et al. The longitudinal association of sleep and 24-hour activity rhythms with cortisol response to a very low dose of dexamethasone[J]. Sleep Health, 2022, 8(4): 398-405. doi: 10.1016/j.sleh.2022.03.002
    [16]
    MAHFOUZ F M, LI T, JODA M, et al. Sleep dysfunction associated with worse chemotherapy-induced peripheral neurotoxicity functional outcomes[J]. Support Care Cancer, 2023, 32(1): 46.
    [17]
    EVENEPOEL M, HAENEN V, DE BAERDEMAECKER T, et al. Pain prevalence during cancer treatment: a systematic review and meta-analysis[J]. J Pain Symptom Manage, 2022, 63(3): e317-e335. doi: 10.1016/j.jpainsymman.2021.09.011
    [18]
    陈文华, 邵晶晶, 陈海珍, 等. 炎症标志物与肺癌伴焦虑抑郁、睡眠障碍、疲乏的相关性研究进展[J]. 肿瘤学杂志, 2023, 29(12): 1023-1027.

    CHEN W H, SHAO J J, CHEN H Z, et al. Research progress on correlation of inflammatory markers withanxiety, depression, sleep disorders and fatigue in lung cancer patients[J]. Journal of Chinese Oncology, 2023, 29(12): 1023-1027.
    [19]
    武文娟, 邵艳敏, 尹小君. 血清TNF-α、IL-6、CRP水平对老年急性脑梗死患者介入治疗后睡眠障碍的预测价值[J]. 东南大学学报(医学版), 2021, 40(6): 760-765.

    WU W J, SHAO Y M, YIN X J. Value of serum TNF-α, IL-6 and CRP levels in predicting sleep disorders in elderly patients with acute cerebral infarction after interventional therapy[J]. Journal of Southeast University(Medical Science Edition), 2021, 40(6): 760-765.
    [20]
    VALLE V I, MAFLA-ESPANA M A, SILVA J, et al. Actigraphy analysis of sleep associates with salivary IL-6 concentration in institutionalized older individuals[J]. Diseases, 2023, 11(3): 93.
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