Volume 23 Issue 2
Feb.  2025
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LI Qi, LUO Guiquan, LIU Lei, TAN Zhen, REN Hongqiang. The effect of catheter radiofrequency ablation on cardiac structure and long-term prognosis in patients with heart failure and persistent atrial fibrillation[J]. Chinese Journal of General Practice, 2025, 23(2): 227-230. doi: 10.16766/j.cnki.issn.1674-4152.003873
Citation: LI Qi, LUO Guiquan, LIU Lei, TAN Zhen, REN Hongqiang. The effect of catheter radiofrequency ablation on cardiac structure and long-term prognosis in patients with heart failure and persistent atrial fibrillation[J]. Chinese Journal of General Practice, 2025, 23(2): 227-230. doi: 10.16766/j.cnki.issn.1674-4152.003873
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The effect of catheter radiofrequency ablation on cardiac structure and long-term prognosis in patients with heart failure and persistent atrial fibrillation

doi: 10.16766/j.cnki.issn.1674-4152.003873

  • Atrial Fibrillation Center, Suining Central Hospital, Suining, Sichuan 629000, China

Funds:

 2019YFS0345

  • Received Date: 2024-02-11
    Available Online: 2025-03-27
    Abstract
  •   Objective  To investigate the impact of catheter radiofrequency ablation (RFA) on cardiac structure and long-term survival in patients with heart failure and persistent atrial fibrillation (AF).  Methods  A retrospective analysis was conducted on 379 patients with heart failure and persistent AF who were hospitalized in the Atrial Fibrillation Center of Suining Central Hospital from January 2017 to May 2019.Based on whether they underwent RFA during their hospitalization, they were further divided into two groups: the RFA group (n=33) and the control group (n=126).The baseline data of both groups were compared.All patients were followed up, and some echocardiographic indicators were compared during hospitalization and follow-up to assess the improvement of cardiac structure.Kaplan-meier survival analysis was used to evaluate the long-term survival of the RFA group and the control group.Multivariate Cox regression analysis was used to correct for confounding factors and assess the impact of RFA on long-term prognosis.  Results  The baseline data of the RFA group and the control group showed comparable results.Compared with admission, the left ventricular end-diastolic diameter and left ventricular ejection fraction in the echocardiographic indicators of the RFA group improved significantly during follow-up, with statistically significant differences (P < 0.05).Among the 4 patients in the RFA group (12.1%) and 39 patients in the control group (31.0%), events occurred at the end of follow-up.Kaplan-meier survival analysis showed that the long-term prognosis of theRFA group was better than that of the control group (P=0.049).Through multivariate Cox regression analysis, adjusting for gender, age, body mass index, left ventricular ejection fraction, and implantable cardioverter defibrillator, it was found that RFA remained an independent factor affecting long-term prognosis (HR=0.335, 95%CI: 0.116-0.964, P=0.043).  Conclusion  RFA can improve the left ventricular structure and ejection fraction in patients with heart failure andpersistent AF, and is an important factor in improving prognosis.

     

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