Volume 23 Issue 7
Jul.  2025
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GUO Jiaqi, LI Shu, DANG Ruixue, HAN Ying, GAO Jingyuan. Effect of transcranial ultrasound stimulation combined with electrical stimulation of different intensity on middle-aged and elderly patients with sleep disorders[J]. Chinese Journal of General Practice, 2025, 23(7): 1094-1097. doi: 10.16766/j.cnki.issn.1674-4152.004072
Citation: GUO Jiaqi, LI Shu, DANG Ruixue, HAN Ying, GAO Jingyuan. Effect of transcranial ultrasound stimulation combined with electrical stimulation of different intensity on middle-aged and elderly patients with sleep disorders[J]. Chinese Journal of General Practice, 2025, 23(7): 1094-1097. doi: 10.16766/j.cnki.issn.1674-4152.004072

Effect of transcranial ultrasound stimulation combined with electrical stimulation of different intensity on middle-aged and elderly patients with sleep disorders

doi: 10.16766/j.cnki.issn.1674-4152.004072
Funds:

 20240760

  • Received Date: 2024-04-11
    Available Online: 2025-10-25
  •   Objective   To improve sleep disorders in middle-aged and elderly people, this study adopted a treatment plan of transcranial ultrasound stimulation (TUS) combined with different intensities of electrical stimulation and explores the therapeutic effect of the combination of two physical methods.   Methods   The research selected 150 middle-aged and elderly patients with sleep disorders who were treated in the Affiliated Hospital of North China University of Science and Technology from November 2021 to February 2024 as the research targets. According to the admission time, the patients were divided into high-intensity group, low-intensity group and control group, with 50 cases in each group. On the basis of the same transcranial ultrasound stimulation, the patients in each group were given different intensities of electrical stimulation, and the treatment lasted for 2 weeks. Compare the scores of the Pittsburgh sleep quality index (PSQI), sleep time, sleep efficiency, PSQI reduction rate, serum cortisol (CORT), and adverse reactions among three groups after treatment.   Results   After treatment, the sleep efficiency of the high-intensity group [80.00 (71.00, 88.00) %] and the low-intensity group [75.00 (70.00, 80.00) %] was better than that of the control group [71.00 (63.75, 78.50) %, P < 0.05]; After treatment, the total PSQI scores of the high-intensity group (6.52±1.39) and the low-intensity group (8.60±1.43) were better than those of the control group (9.74±2.43, P < 0.05). The PSQI reduction rates in the low-intensity group [(37.65±9.28) %] and the high-intensity group [(52.51±9.36) %] were higher than those in the control group [(31.19±12.26) %, P < 0.05]. After treatment, the CORT levels in the high-intensity group [(10.28±2.21) μg/dL] and the low-intensity group [(12.66±2.85) μg/dL] were both better than those in the control group [(15.18±2.78) μg/dL, P < 0.05]. During the treatment period, there was no statistically significant difference in the incidence of adverse reactions among the three groups (P>0.05).   Conclusion   Transcranial ultrasound stimulation combined with electrical stimulation can improve sleep disorders in patients, and the intensity of electrical stimulation is directly proportional to the therapeutic effect. The combination of transcranial ultrasound stimulation and electrical stimulation is more effective in reducing CORT levels in patients than transcranial ultrasound stimulation alone.

     

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