Volume 23 Issue 9
Sep.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(9): 1591-1594
LIU Mengyu, SUN Xiaoqiao, HUO Rui. Summary of the best evidence for managing low anterior resection syndrome in patients after rectal cancer sphincter-saving surgery[J]. Chinese Journal of General Practice, 2025, 23(9): 1591-1594. doi: 10.16766/j.cnki.issn.1674-4152.004184
Citation: LIU Mengyu, SUN Xiaoqiao, HUO Rui. Summary of the best evidence for managing low anterior resection syndrome in patients after rectal cancer sphincter-saving surgery[J]. Chinese Journal of General Practice, 2025, 23(9): 1591-1594. doi: 10.16766/j.cnki.issn.1674-4152.004184
shu

Summary of the best evidence for managing low anterior resection syndrome in patients after rectal cancer sphincter-saving surgery

doi: 10.16766/j.cnki.issn.1674-4152.004184
  • 1.

    Bengbu Medical University School of Nursing, Bengbu, Anhui 233030, China

Funds:

 AHWJ2023BAa20078

  • Received Date: 2024-09-24
    Available Online: 2025-11-17
    Abstract
  •   Objective  Retrieve and summarize the highest evidence from both domestic and international sources on the management of patients with LARS, in order to provide a basis for clinical practice.  Methods  The PIPOST was adopted to establish evidence-based problems, and the "6S" pyramid evidence model was adopted. The system conducted a comprehensive search across various databases including UpToDate, BMJ Best Practice, Cochrane Library, Web of Science, PubMed, Embase, CINAHL, NICE, ASCRS, American Medical Association, Chinese Biomedical Literature Database, Yimaitong, CNKI, Wanfang, and VIP, focusing on the management of patients experiencing low anterior resection syndrome after rectal preservation surgery, including clinical decisions, guidelines, systematic reviews, expert consensus, and original research. Two team members independently completed the literature quality evaluation using corresponding literature quality evaluation tools and extracted relevant evidence. The evidence was summarized and evaluated using the grading and recommendation system established by the JBI Evidence-Based Health Care Center. The search period is up to August 2024.  Results  In this study, 4 166 literature were obtained through a systematic search of relevant databases, and screening in accordance with inclusion and exclusion criteria, a total of 13 studies were definitively incorporated into the final analysis for medical evaluation, including 1 clinical decision, 4 guidelines, 2 expert consensus, 3 systematic reviews, and 3 original studies. The extraction content included multidisciplinary cooperation and evaluation, pelvic floor rehabilitation management, diet management, health education, monitoring, and follow-up, and a total of 21 best evidence were collected.  Conclusion  This study summarizes the evidence for managing patients with LARS. It aims to provide an evidence-based foundation for developing a comprehensive and scientific management protocol for patients, ultimately promoting their overall rehabilitation.

     

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