Volume 29 Issue 10
Oct.  2025
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(10): 1643-1646
Dilidare·Aierken, Xiherezhati·Abulimiti, TIAN Ruisi. Analysis of influencing factors and predictive value of in-hospital acute ischemic stroke[J]. Chinese Journal of General Practice, 2025, 23(10): 1643-1646. doi: 10.16766/j.cnki.issn.1674-4152.004195
Citation: Dilidare·Aierken, Xiherezhati·Abulimiti, TIAN Ruisi. Analysis of influencing factors and predictive value of in-hospital acute ischemic stroke[J]. Chinese Journal of General Practice, 2025, 23(10): 1643-1646. doi: 10.16766/j.cnki.issn.1674-4152.004195
shu

Analysis of influencing factors and predictive value of in-hospital acute ischemic stroke

doi: 10.16766/j.cnki.issn.1674-4152.004195

  • Department of Rehabilitation Medicine, the Second Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830000, China

Funds:

 2022D01C276

  • Received Date: 2025-01-28
    Abstract
  •   Objective  Given that in-hospital acute ischemic stroke (IHS) is often associated with diagnostic delays and poor prognosis due to patients' complex underlying conditions and specific treatment backgrounds, this study aims to identify independent risk factors for IHS and evaluate their predictive value, so as to provide a basis for early clinical identification and intervention.  Methods  A retrospective analysis was conducted on 85 cases of acute ischemic stroke admitted to the Department of Neurology of the Second Affiliated Hospital of Xinjiang Medical University, from January 2015 to January 2020. The 85 cases were included as the in-hospital group, and 170 cases hospitalized due to acute ischemic stroke during the same period were selected as the control group (out-of-hospital group). The general information between the two groups of patients was analyzed. Logistic regression was used to analyze the factors of in-hospital acute ischemic stroke. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of each factor for acute ischemic stroke in the hospital.  Results  Cardiac insufficiency (OR=5.202, 95% CI: 1.436-18.849), mRS score at onset (≥3 points, OR=3.602, 95% CI: 1.809-7.175), perioperative period (OR=4.085, 95% CI: 1.391-11.997), combined anterior and posterior circulation infarction (OR=1.959, 95% CI: 1.270-3.022), and cardiogenic embolism (OR=2.312, 95% CI: 1.257-4.253) were identified as independent risk factors for the occurrence of acute ischemic stroke in hospital (P<0.05). The AUCs of IHS for cardiac insufficiency, high mRS score at onset, perioperative period, combined anterior and posterior circulation infarction, and cardiogenic embolism were 0.705, 0.720, 0.736, 0.751 and 0.782, respectively. The combined prediction of all five indicators yielded an AUC of 0.913.  Conclusion  Cardiac insufficiency, mRS score at onset, perioperative period, combined anterior and posterior circulation infarction, and cardiogenic embolic infarction are independent risk factors affecting the occurrence of IHS. These factors have certain significant predictive value for the occurrence of IHS.

     

    • FullText(HTML)
  • loading
    • References(17)
  • [1]
    CHAPMAN L, KENNEDY O, BRADLEY D, et al. Clinical validation of in-hospital stroke diagnosis[J]. J Stroke Cerebrovasc Dis, 2023, 32(9): 107278. DOI: 10.1016/j.jstrokecerebrovasdis.2023.107278.
    [2]
    GARG A, ROEDER H, LEIRA E C. In-hospital outcomes and recurrence of stroke during pregnancy and puerperium[J]. Int J Stroke, 2023, 18(4): 445-452. doi: 10.1177/17474930221116209
    [3]
    余文娟, 郑红建, 余双娟, 等. 脑卒中后吞咽障碍患者PG-SGA评分与不良预后风险的相关性[J]. 中华全科医学, 2024, 22(4): 586-588, 681. doi: 10.16766/j.cnki.issn.1674-4152.003456

    YU W J, ZHENG H J, YU S J, et al. Correlation between PG-SGA score and risk of poor prognosis in post-stroke dysphagia patients[J]. Chinese Journal of General Practice, 2024, 22(4): 586-588, 681. doi: 10.16766/j.cnki.issn.1674-4152.003456
    [4]
    刘凯, 王伊龙, 李子孝, 等. 尿激酶静脉溶栓治疗急性缺血性卒中/短暂性脑缺血发作的院内死亡率及相关影响因素的多中心分析[J]. 中国卒中杂志, 2020, 15(10): 1078-1082.

    LIU K, WANG Y L, LI Z X, et al. Multi center analysis of in-hospital mortality and related influencing factors in the treatment of acute ischemic stroke/transient ischemic attack with intravenous thrombolysis with urokinase[J]. Chinese Journal of Stroke, 2020, 15(10): 1078-1082.
    [5]
    中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2018[J]. 中华神经科杂志, 2018, 51(9): 666-682.

    Chinese Medical Association Neurology Branch, Cerebrovascular Disease Group of Chinese Medical Association Neurology Branch Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2023[J]. Chinese Journal of Neurology, 2018, 51(9): 666-682.
    [6]
    何家礼, 莫云. 卒中单元院前急救流程对提高急性缺血性脑卒中患者静脉溶栓效果的分析[J]. 中外医药研究, 2023, 2(33): 121-123.

    HE J L, MO Y. Analysis of the effect of pre hospital emergency procedures in stroke units on improving the effectiveness of intravenous thrombolysis in patients with acute ischemic stroke[J]. Chinese and Foreign Medical Research, 2023, 2(33): 121-123.
    [7]
    李宏建. 2型糖尿病患者的首次卒中风险及其与血糖控制的关系[J]. 国际脑血管病杂志, 2020, 28(3): 167.

    LI H J. Risk of first stroke and its relationship with blood glucose control in patients with type 2 diabetes[J]. International Journal of Cerebrovascular Disease, 2020, 28(3): 167.
    [8]
    张俊青, 魏亚琳, 张丽娜, 等. 睡眠时间及体力活动与缺血性脑卒中的相关性研究进展[J]. 青岛大学学报(医学版), 2020, 56(5): 627-630.

    ZHANG J Q, WEI Y L, ZHANG L N, et al. Research progress on the correlation between sleep time, physical activity and ischemic stroke[J]. Journal of Qingdao University (Medical Edition), 2020, 56(5): 627-630.
    [9]
    孙瑶, 杨志明. 窦性心律心力衰竭患者脑卒中风险评估的研究进展[J]. 心血管病学进展, 2023, 44(6): 528-531, 550.

    SUN Y, YANG Z M. Research progress on stroke risk assessment in patients with sinus rhythm heart failure[J]. Advances in Cardiovascular Diseases, 2023, 44(6): 528-531, 550.
    [10]
    金铁, 丁继, 崔凯, 等. 环状RNA CDC14A表达与急性缺血性脑卒中发生风险、严重程度及复发的相关性研究[J]. 心脑血管病防治, 2024, 24(2): 50-53.

    JIN T, DING J, CUI K, et al. The correlation between the expression of circular RNA CDC14A and the risk, severity, and recurrence of acute ischemic stroke[J]. Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, 2024, 24(2): 50-53.
    [11]
    龚倩倩, 宋春江, 龙秀英, 等. 恶性肿瘤相关性脑梗死的临床特点及相关危险因素分析[J]. 肿瘤预防与治疗, 2019, 32(2): 193-198.

    GONG Q Q, SONG C J, LONG X Y, et al. Analysis of the clinical characteristics and related risk factors of cerebral infarction associated with malignant tumors[J]. Cancer Prevention and Treatment, 2019, 32(2): 193-198.
    [12]
    曹志明, 万小旭, 刘艳芳. 急性缺血性脑卒中患者卒中后抑郁简易风险评分系统的构建[J]. 内蒙古医学杂志, 2023, 55(9): 1029-1034.

    CAO Z M, WAN X X, LIU Y F Construction of a simplified risk scoring system for post-stroke depression in patients with acute ischemic stroke[J]. Inner Mongolia Medical Journal, 2023, 55(9): 1029-1034.
    [13]
    李辉. 重视围手术期脑卒中的识别与管理[J]. 中华外科杂志, 2024, 62(7): 619-623.

    LI H. Pay attention to the identification and management of perioperative stroke[J]. Chinese Journal of Surgery, 2024, 62(7): 619-623.
    [14]
    韦紫君, 东格尔·雅其乐, 曹孟欣, 等. 首次发病前循环、后循环急性小动脉闭塞性脑卒中病人的临床特点和预后比较[J]. 中西医结合心脑血管病杂志, 2022, 20(19): 3615-3619.

    CAO M X, YAO Y Y, WANG Y, et al. Comparison of clinical characteristics and prognosis of patients with acute small artery occlusion stroke before and after the first onset of circulation[J]. Journal of Integrated Traditional Chinese and Western Medicine for Cardiovascular and Cerebrovascular Diseases, 2022, 20(19): 3615-3619.
    [15]
    任婧, 邵枝定, 许忠强. 前、后循环颅内动脉粥样硬化的缺血性卒中患者的预后观察[J]. 局解手术学杂志, 2022, 31(7): 591-595.

    REN J, SHAO Z D, XU Z Q. Prognostic observation of ischemic stroke patients with anterior and posterior circulation intracranial atherosclerosis[J]. Journal of Surgical Surgery, 2022, 31(7): 591-595.
    [16]
    张咪咪, 李妮妮. 心源性脑卒中危险因素分析及预防对策探讨[J]. 贵州医药, 2020, 44(11): 1754-1755.

    ZHANG M M, LI N N. Analysis of risk factors and exploration of prevention strategies for cardiogenic stroke[J]. Guizhou Pharmaceutical, 2020, 44(11): 1754-1755.
    [17]
    曹誉竞, 陈灏. 心源性卒中诊疗的研究进展[J]. 临床医学进展, 2023, 13(5): 7069-7077.

    CAO Y J, CHEN H. Research progress on diagnosis and treatment of cardiogenic stroke[J]. Clinical Medical Progress, 2023, 13(5): 7069-7077.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (24) PDF downloads(2) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return