Volume 29 Issue 10
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(10): 1717-1720
XU Yaqian, SONG Mingxia, HAN Cheng. Clinical study on the effect of prebiotics on gastrointestinal recovery after laparoscopic exploration for benign gynecological diseases[J]. Chinese Journal of General Practice, 2025, 23(10): 1717-1720. doi: 10.16766/j.cnki.issn.1674-4152.004213
Citation: XU Yaqian, SONG Mingxia, HAN Cheng. Clinical study on the effect of prebiotics on gastrointestinal recovery after laparoscopic exploration for benign gynecological diseases[J]. Chinese Journal of General Practice, 2025, 23(10): 1717-1720. doi: 10.16766/j.cnki.issn.1674-4152.004213
shu

Clinical study on the effect of prebiotics on gastrointestinal recovery after laparoscopic exploration for benign gynecological diseases

doi: 10.16766/j.cnki.issn.1674-4152.004213
  • 1.

    Obstetrics and Gynecology Department of Hangzhou First People's Hospital, Hangzhou, Zhejiang 310006, China

Funds:

 2023KY922

  • Received Date: 2024-08-18
    Abstract
  •   Objective  To assess the effect of prebiotics on gastrointestinal function recovery following laparoscopic exploration for benign gynecological diseases, and to provide evidence for optimizing postoperative rehabilitation strategies.  Methods  According to the inclusion and exclusion criteria, 140 patients with laparoscopic exploration at the Department of Gynecology of Hangzhou First People ' s Hospital from September 2022 to September 2023, were randomly divided into an intervention group (prebiotic treatment) and a control group (placebo), with 70 cases in each group. Time to first postoperative flatus and defecation, gastrointestinal quality of life index (GIQLI), and the incidence of postoperative adverse reactions were compared between the two groups.  Results  The time to first flatus [(1.50±0.45) h vs. (2.75±1.20) h] and the first defecation time [(2.43±0.52) h vs. (3.58±0.61) h] in the intervention group were shorter than those in the control group (P < 0.05), respectively. One week after discharge, the score of physical dimension in the intervention group was higher than that in the control (77.87±9.19 vs. 68.10±9.67, P < 0.05). The GIQLI scores of the intervention group at discharge (55.94±15.34 vs. 63.50±18.27) and one week after discharge (50.84±11.67 vs. 55.24±11.24) were lower than those of the control group (P < 0.05). The overall incidence of adverse reactions (abdominal distension, abdominal pain, vomiting, intestinal obstruction, etc.) in the control group was significantly higher than those in the intervention group [15.71% (11/70) vs. 2.86% (2/70), P < 0.05].  Conclusion  Prebiotic intervention can significantly shorten the first exhaust and defecation time of patients with gynecological benign diseases after laparoscopic surgery, reduce the incidence of gastrointestinal adverse reactions such as postoperative abdominal distension and abdominal pain, and improve the early postoperative quality of life of patients.

     

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