The relationship between nutritional status and coronary atherosclerotic heart disease in young and middle-aged people

DENG Jie; LIU Xiaoming; LU Wei

doi:10.16766/j.cnki.issn.1674-4152.004239

Volume 23 Issue 11

Nov. 2025

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DENG Jie, LIU Xiaoming, LU Wei. The relationship between nutritional status and coronary atherosclerotic heart disease in young and middle-aged people[J]. Chinese Journal of General Practice, 2025, 23(11): 1834-1837. doi: 10.16766/j.cnki.issn.1674-4152.004239

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DENG Jie, LIU Xiaoming, LU Wei. The relationship between nutritional status and coronary atherosclerotic heart disease in young and middle-aged people[J]. Chinese Journal of General Practice, 2025, 23(11): 1834-1837. doi: 10.16766/j.cnki.issn.1674-4152.004239

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The relationship between nutritional status and coronary atherosclerotic heart disease in young and middle-aged people

doi: 10.16766/j.cnki.issn.1674-4152.004239

DENG Jie^{1, 2}
, LIU Xiaoming^{1
,
,}
, LU Wei^{1, 2}

1.
School of Clinical Medicine, North China University of Science and Technology, Tangshan, Hebei 063000, China

Funds:

20231798

Received Date: 2024-11-23
Available Online: 2026-01-07

Abstract

Abstract

In recent years, the incidence of coronary artery disease (CAD) has gradually become younger, especially in young and middle-aged people aged 35 to 45. Young and middle-aged patients with CAD have an acute onset, a high risk of sudden death, and a worse prognosis. Nutrition has been identified as one of the main risk factors affecting CAD. More than 70% of hospitalized patients with CAD are at risk of nutritional imbalance. Since nutrition is an important modifiable factor through behavioral intervention, it seems to be the best intervention target for CAD. The purpose of this review is to summarize the use of controlling nutritional status (CONUT), the relationship between malnutrition, micronutrients (especially vitamin D, folic acid, vitamin B₁₂, zinc, iron, and selenium) levels and coronary heart disease, and the effect of these nutrient supplementation on the prognosis of coronary heart disease. Malnutrition, micronutrients (especially vitamin D, folic acid and vitamin B₁₂, zinc, selenium, etc.) levels are significantly associated with the prognosis of CAD. Folic acid supplementation can improve cardiovascular health, but the beneficial effects of vitamin D, vitamin B₁₂, and zinc supplementation on cardiovascular health are still controversial. These conflicting results may be related to population characteristics, comorbidities, cardiovascular disease categories, nutritional status, and nutritional supplementation regimens. Appropriate nutrition combined with lifestyle management is still recommended to prevent cardiovascular disease and promote cardiovascular health.
- Coronary atherosclerotic heart disease,
- Young and middle-aged,
- Nutritional status,
- Nutritional imbalances,
- Nutritional management

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References(41)

References

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The relationship between nutritional status and coronary atherosclerotic heart disease in young and middle-aged people

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