Volume 23 Issue 11
Nov.  2025
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(11): 1838-1841
XU Jinjuan, WU Liping, DONG Guoli, WANG Gang. Development trajectory of heart rate deceleration force in elderly patients with stable coronary heart disease and its influencing factors[J]. Chinese Journal of General Practice, 2025, 23(11): 1838-1841. doi: 10.16766/j.cnki.issn.1674-4152.004240
Citation: XU Jinjuan, WU Liping, DONG Guoli, WANG Gang. Development trajectory of heart rate deceleration force in elderly patients with stable coronary heart disease and its influencing factors[J]. Chinese Journal of General Practice, 2025, 23(11): 1838-1841. doi: 10.16766/j.cnki.issn.1674-4152.004240
shu

Development trajectory of heart rate deceleration force in elderly patients with stable coronary heart disease and its influencing factors

doi: 10.16766/j.cnki.issn.1674-4152.004240

  • Department of General Geriatrics, Linping District Integrated Traditional Chinese and Western Medicine Hospital, Hangzhou, Zhejiang 311100, China

Funds:

 2024XY128

  • Received Date: 2024-11-21
    Available Online: 2026-01-07
    Abstract
  •   Objective  Based on the latent category growth model (LCGM), this study analyzed the development trajectory of heart rate deceleration force (DC) in elderly patients with stable coronary heart disease (SCAD) and explored factors affecting its development, thereby providing a reference for future treatment strategies for elderly SCAD patients.  Methods  A total of 185 elderly patients with SCAD who were treated in Linping District Integrated Traditional Chinese and Western Medicine Hospital from February 2020 to February 2023 were selected as the research objects. Clinical data and DC values of patients were collected. The differences in DC values of patients at different time points were analyzed. LCGM was applied to explore the potential trajectory subgroups of patients' DC values, and the factors affecting the trajectory subgroups were analyzed by univariate and multivariate analysis.  Results  With the extension of follow-up time, DC value increased gradually, and there were significant differences in DC value at each time point (F=182.301, P < 0.001). LCGM consensus identified three potential change paths of DC value-rapid increase group (subgroup 1), medium DC value-sustained stability group (subgroup 2), and low DC value-slow increase group (subgroup 3). Significant differences in the duration of coronary heart disease, number of lesions, Gensini score, FBG, Hcy, TG, Chemerin, and APN among the 3 subgroups (P < 0.05). Compared with subgroup 1, the main influencing factors for subgroup 3 and subgroup 2 were the number of lesions, Gensini score, TG, Chemerin, and APN (P < 0.05).  Conclusion  Elderly patients with SCAD exhibit different trajectories of DC value change. It is recommended to conduct targeted assessment and intervention based on the homogenous group of elderly patients with SCAD DC value change trajectories to improve patient prognosis.

     

    • FullText(HTML)
  • loading
    • References(19)
  • [1]
    HASBANI N R, LIGTHART S, BROWN M R, et al. American Heart Association's Life's simple 7: lifestyle recommendations, polygenic risk, and lifetime risk of coronary heart disease[J]. Circulation, 2022, 145(11): 808-818. doi: 10.1161/CIRCULATIONAHA.121.053730
    [2]
    Writing Committee of the Report on Cardiovascular Health and Diseases in China. Report on cardiovascular health and diseases in China 2022: an updated summary[J]. Biomed Environ Sci, 2023, 36(8): 669-701.
    [3]
    陈西, 羡微微, 盛勇, 等. 冠心病患者经皮冠状动脉介入术相关造影剂急性肾损害的影响因素分析及KIM-1、NGAL、NHE3的预测价值[J]. 中国现代医学杂志, 2024, 34(4): 51-57.

    CHEN X, XIAN W W, SHENG Y, et al. Factors affecting the occurrence of contrast-induced acute kidney injury related to PCI in patients with coronary heart disease and predictive values of KIM-1, NGAL and NHE3[J]. China Journal of Modern Medicine, 2024, 34(4): 51-57.
    [4]
    HE J N, SONG C X, ZHANG R, et al. Discordance between neutrophil to lymphocyte ratio and high sensitivity C-reactive protein to predict clinical events in patients with stable coronary artery disease: a large-scale cohort study[J]. J Inflamm Res, 2023, 16: 5439-5450. doi: 10.2147/JIR.S428734
    [5]
    GOYAL P, NANNA M G. Stable coronary artery disease in the age of geriatric cardiology[J]. J Am Coll Cardiol, 2023, 81(17): 1710-1713. doi: 10.1016/j.jacc.2023.03.378
    [6]
    MILARAS N, DOURVAS P, DOUNDOULAKIS I, et al. Noninvasive electrocardiographic risk factors for sudden cardiac death in dilated ca rdiomyopathy: is ambulatory electrocardiography still relevant?[J]. Heart Fail Rev, 2023, 28(4): 865-878. doi: 10.1007/s10741-023-10300-x
    [7]
    VAN HELMONDT S J, LODDER P, VAN WOEZIK R, et al. CBT-based online self-help training to reduce fear and distress after cancer (CAREST Randomized Trial): 24 months follow-up using latent growth models and latent class analysis[J]. Ann Behav Med, 2023, 57(9): 787-799. doi: 10.1093/abm/kaac078
    [8]
    中国医师协会心血管内科医师分会双心学组, 北京医学会心脏心理分会. 稳定性冠心病合并心理问题基层诊疗共识(2023年)[J]. 中华全科医师杂志, 2023, 22(12): 1224-1234.

    Psycho-cardiology Group, Branch of Cardiovascular Physicians of Chinese Medical Doctor Association, Psycho-cardiology Group of Beijing Medical Association. Expert consensus on diagnosis and treatment of stable coronary artery disease combined with mental disorders in primary care (2023 edition)[J]. Chinese Journal of General Practitioners, 2023, 22(12): 1224-1234.
    [9]
    李双双, 马依彤, 吴婷婷, 等. 基线血红蛋白水平对老年冠心病患者远期临床预后的影响[J]. 临床内科杂志, 2023, 40(9): 598-602.

    LI S S, MA Y T, WU T T, et al. Effect of baseline hemoglobin levels on long-term clinical outcome in elderly patients with coronary heart disease[J]. Journal of Clinical Internal Medicine, 2023, 40(9): 598-602.
    [10]
    KELSEY M D, KELSEY A M. Diagnosing coronary artery disease in the patient presenting with stable ischemic heart disease: the role of anatomic versus functional testing[J]. Med Clin North Am, 2024, 108(3): 427-439. doi: 10.1016/j.mcna.2023.11.002
    [11]
    GAUDINO M, AUDISIO K, HUEB W A, et al. Coronary artery bypass grafting versus medical therapy in patients with stable coronary artery disease: an individual patient data pooled meta-analysis of randomized trials[J]. J Thorac Cardiovasc Surg, 2024, 167(3): 1022-1032. doi: 10.1016/j.jtcvs.2022.06.003
    [12]
    MIZERA L, RATH D, SCHREIECK J, et al. Deceleration capacity of heart rate predicts 1-year mortality in patients undergoing transcatheter edge-to-edge mitral valve repair[J]. Clin Cardiol, 2023, 46(5): 529-534. doi: 10.1002/clc.24007
    [13]
    陈超, 魏玉娇, 王安阳, 等. ApoA1/ApoB与ST段抬高型心肌梗死病人冠脉病变程度的相关性[J]. 青岛大学学报(医学版), 2023, 59(5): 745-748.

    CHEN C, WEI Y J, WANG A Y, et al. Relationship between ApoA1-to-ApoB ratio and the severity of coronary artery disease in patients with ST-segment elevation myocardial infarction[J]. Journal of Qingdao University(Medical Sciences), 2023, 59(5): 745-748.
    [14]
    管晶晶, 时鹏, 李保伍, 等. 颈动脉粥样硬化斑块超声联合血脂指标对心血管疾病的预测价值评估[J]. 中华全科医学, 2022, 20(8): 1376-1379.

    GUAN J J, SHI P, LI B W, et al. Value evaluation of carotid atherosclerotic plaque ultrasound combined with blood lipid index in predicting cardiovascular disease[J]. Chinese Journal of General Practice, 2022, 20(8): 1376-1379.
    [15]
    高振华, 靳飞鹏, 孟银苔, 等. 血清sST2、H-FABP、Clusterin对冠心病患者PCI术后主要不良心血管事件的预测价值分析[J]. 医药论坛杂志, 2023, 44(17): 9-13.

    GAO Z H, JIN F P, MENG Y T, et al. Predictive value of serum sST2, H-FABP and Clusterin on major adverse cardiovascular events in patients with coronary heart disease after PC[J]. Journal of Medical Forum, 2023, 44(17): 9-13.
    [16]
    彭昊帅, 赖耀文, 张艳, 等. 阿托伐他汀钙序贯用药辅助支架植入治疗对冠心病患者疗效及心肌微循环的影响[J]. 医药论坛杂志, 2023, 44(2): 27-30.

    PENG H S, LAI Y W, ZHANG Y, et al. Effect of atorvastatin calcium sequential therapy assisted stent implantation on efficacy and myocardial microcirculation in patients with coronary heart disease[J]. Journal of Medical Forum, 2023, 44(2): 27-30.
    [17]
    FAJKIĆ A, LEPARA O, DERVISEVIĆ A, et al. Relationship between adipocytokines, nontraditional anthropometric indices and coronary heart disease risk in diabetic patients[J]. Curr Health Sci J, 2022, 48(4): 365-372.
    [18]
    ISMAIEL A, ASHFAQ M Z, LEUCUTA D C, et al. Chemerin levels in acute coronary syndrome: systematic review and meta-analysis[J]. Lab Med, 2022, 53(6): 552-560. doi: 10.1093/labmed/lmac059
    [19]
    付彦. 2型糖尿病合并急性脑梗死患者颈动脉粥样硬化及血清脂联素、可溶性细胞间黏附分子-1和可溶性血管细胞间黏附分子-1水平分析[J]. 新乡医学院学报, 2020, 37(7): 674-677.

    FU Y. Analysis of carotid atherosclerosis and the levels of serum adiponectin, soluble intercellular adhesion molecule-1 and soluble vascular cell adhesionmolecula-1 in patients with type 2 diabetes mellitus complicated with acute cerebral infarction[J]. Journal of Xinxiang Medical University, 2020, 37(7): 674-677.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(1)  / Tables(4)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (49) PDF downloads(0) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return