Volume 23 Issue 11
Nov.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(11): 1878-1881
SU Afang, LI Guangjian, ZHANG Yunshui, WU Shouling, JIANG Xiaozhong. Study on the association between the Chinese visceral adiposity index and the risk of acute pancreatitis[J]. Chinese Journal of General Practice, 2025, 23(11): 1878-1881. doi: 10.16766/j.cnki.issn.1674-4152.004250
Citation: SU Afang, LI Guangjian, ZHANG Yunshui, WU Shouling, JIANG Xiaozhong. Study on the association between the Chinese visceral adiposity index and the risk of acute pancreatitis[J]. Chinese Journal of General Practice, 2025, 23(11): 1878-1881. doi: 10.16766/j.cnki.issn.1674-4152.004250
shu

Study on the association between the Chinese visceral adiposity index and the risk of acute pancreatitis

doi: 10.16766/j.cnki.issn.1674-4152.004250
  • 1.

    Department of Gastroenterology, Kailuan General Hospital, Tangshan, Hebei 063000, China

Funds:

 20221582

  • Received Date: 2024-10-19
    Available Online: 2026-01-07
    Abstract
  •   Objective  Visceral fat is mostly related to metabolic disorders. This study aimed to explore the relationship between the chinese visceral adiposity index (CVAI) in the Chinese population and the risk of acute pancreatitis (AP).  Methods  A total of 123 461 eligible participants from the Kailuan cohort who participated their first physical examination between 2006 and 2009 were included. Participants were divided into four groups according to the CVAI quartile level. Group Q1 (31 015 cases, CVAI≤7.07 mmol/L), Group Q2 (30 817 cases, 7.07 mmol/L < CVAI≤38.92 mmol/L), Group Q3 (30 816 cases, 38.92 mmol/L < CVAI≤70.74 mmol/L), and Group Q4 (30 813 cases, CVAI>70.74 mmol/L). The cumulative incidence of AP was calculated by Kaplan-Meier method and compared across groups with the log-rank. Multivariate Cox proportional hazard regression model was applied to analyze the evaluated the association between CVAI quartiles and incident AP during follow-up.  Results  Over a mean followed up period of (13.71±2.65) years, 418 cases of AP were identified among 123 416 participants. There were significant differences in the cumulative incidence of AP were observed among the four CVAI quartile groups (χ2=8.862, P=0.031). Multivariate analysis showed that participants in the Q4 group had a significantly high risk of AP (HR=1.504, 95% CI: 1.126-2.010, P=0.006) compared to the Q1 group. In males, the HR (95% CI) for AP in the Q4 group was 1.368 (95% CI: 1.007-1.858, P=0.045). After excluding AP cases that occurred within 2 years of follow-up, the association remained significant (HR=1.553, 95% CI: 1.141-2.112, P=0.005).  Conclusion  Higher CVAI are associated with an increased risk of acute pancreatitis. CVAI may serve as an effective indicator for identifying individuals at elevated risk of AP disease.

     

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