Volume 23 Issue 11
Nov.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(11): 1885-1888
LOU Chunhua, LU Yuehong, CHEN Huijuan, LIN Hongmei. Expression characteristics and diagnostic significance of serum AMH, TyG index and LAP in patients with polycystic ovary syndrome complicated with metabolic syndrome[J]. Chinese Journal of General Practice, 2025, 23(11): 1885-1888. doi: 10.16766/j.cnki.issn.1674-4152.004252
Citation: LOU Chunhua, LU Yuehong, CHEN Huijuan, LIN Hongmei. Expression characteristics and diagnostic significance of serum AMH, TyG index and LAP in patients with polycystic ovary syndrome complicated with metabolic syndrome[J]. Chinese Journal of General Practice, 2025, 23(11): 1885-1888. doi: 10.16766/j.cnki.issn.1674-4152.004252
shu

Expression characteristics and diagnostic significance of serum AMH, TyG index and LAP in patients with polycystic ovary syndrome complicated with metabolic syndrome

doi: 10.16766/j.cnki.issn.1674-4152.004252
  • 1.

    Women's Health Care Department, Shaoxing Maternal and Child Health Hospital, Shaoxing, Zhejiang 312000, China

Funds:

 2023KY368

  • Received Date: 2025-02-25
    Available Online: 2026-01-07
    Abstract
  •   Objective  People with polycystic ovary syndrome (PCOS) are prone to metabolic syndrome (MS). This study explores the diagnostic and evaluation value of serum anti-Miller's hormone (AMH), triglyceride-glucose (TyG) index and lipid accumulation index (LAP) for PCOS combined with MS.  Methods  A total of 159 patients with PCOS admitted to Shaoxing Maternal and Child Health Hospital from January 2023 to December 2024 were selected and divided into the PCOS group and the PCOS combined with MS group based on whether they were combined with MS, with 97 and 62 cases respectively. The general data, positive rate of MS components, serum AMH, TyG index, and LAP of the two groups were compared. Multivariate logistic regression was used to analyze the influencing factors of PCOS patients complicated with MS. The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic efficacy of serum AMH, TyG index and LAP for PCOS complicated with MS.  Results  The positive rates of triglycerides (TG), high-density lipoprotein (HDL-C), hyperglycemia, the proportion of infertility, BMI, fasting insulin (FINS), and insulin resistance (HOMA-IR) in the PCOS combined with MS group were all higher than those in the PCOS group (P < 0.05). The serum AMH [(15.23±3.27) ng/mL vs. (5.86±1.70)ng/mL], TyG index (9.15±0.48 vs. 8.32±0.45), and LAP (85.26±21.14 vs. 30.84±9.73) were all higher than those in the PCOS group (P < 0.05). HOMA-IR, AMH, TyG index and LAP were independent influencing factors for PCOS combined with MS (P < 0.05). The AUC of the combined diagnosis of PCOS combined with MS by AMH, TyG index and LAP was all higher than the AUC of the individual indicators (P < 0.05).  Conclusion  The serum AMH, TyG index and LAP of patients with PCOS combined with MS are abnormally elevated. The combined detection of the three provides a basis for the clinical assessment of the risk of MS occurrence and diagnosis.

     

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