Volume 23 Issue 11
Nov.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(11): 1896-1899
XIE Junzhe, ZHANG Chunlian, FAN Jifeng, FENG Xiaoyun. Distribution and management strategies of thyroid dysfunction among elderly residents based on health examinations[J]. Chinese Journal of General Practice, 2025, 23(11): 1896-1899. doi: 10.16766/j.cnki.issn.1674-4152.004255
Citation: XIE Junzhe, ZHANG Chunlian, FAN Jifeng, FENG Xiaoyun. Distribution and management strategies of thyroid dysfunction among elderly residents based on health examinations[J]. Chinese Journal of General Practice, 2025, 23(11): 1896-1899. doi: 10.16766/j.cnki.issn.1674-4152.004255
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Distribution and management strategies of thyroid dysfunction among elderly residents based on health examinations

doi: 10.16766/j.cnki.issn.1674-4152.004255
  • 1.

    Department of Endocrinology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China

Funds:

 20ZR1444400

 2023SJKJGG043

  • Received Date: 2024-10-23
    Available Online: 2026-01-07
    Abstract
  •   Objective  The prevalence of thyroid dysfunction increases with age, but the impact of different thyroid stimulating hormone (TSH) thresholds on health outcomes remains controversial. This study investigates the distribution of thyroid dysfunction and explore primary care management strategies based on the health examination data of 3 830 elderly residents from Dongjing Town, Songjiang District, Shanghai, in 2023.  Methods  Subclinical hypothyroidism (SCH) was defined using TSH cut-offs of 4.2, 6.0, 8.0, and 10.0 mIU/L. Health status and cognitive function were compared among residents with different thyroid function states, and clinical and laboratory indicators were analyzed between the SCH group and the euthyroid control group.  Results  At all TSH thresholds, the red cell distribution width (RDW) in the SCH group was significantly higher than in controls (P < 0.05). When TSH≥6.0 mIU/L, the prevalence of cardiac enlargement in the SCH group was 45.6% (47/103), higher than 29.8% (31/104) in control group (χ2=5.518, P=0.019). When TSH≥8.0 mIU/L, hypertension prevalence was 52.7% (29/55) in the SCH group versus 30.9% (17/55) in control group (χ2=5.380, P=0.020), while diabetes prevalence was 5.5% (3/55) versus 18.2% (10/55, χ2=4.274, P=0.039). When TSH≥10.0 mIU/L, significant differences were observed between SCH and control groups in waist circumference, lipid profiles, and the incidence of sinus bradycardia (P < 0.05).  Conclusion  Elderly residents in Dongjing Town, Songjiang District, Shanghai, have better thyroid health than the national average. When TSH < 10.0 mIU/L, overall health status and cognitive function show no significant differences. Regular monitoring of elderly hypothyroid patients is recommended to prevent iatrogenic risks from overtreatment.

     

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