Volume 23 Issue 12
Dec.  2025
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Article Navigation >  Chinese Journal of General Practice  > 2025  >  23(12): 2064-2068
WANG Yan, WU Xiaoxue, LIN Yuanyuan, LI Jianmei, XIE Yanhong. The effect of whey protein and ω-3 fatty acids combined with resistance exercise on the function of elderly sarcopenia patients[J]. Chinese Journal of General Practice, 2025, 23(12): 2064-2068. doi: 10.16766/j.cnki.issn.1674-4152.004292
Citation: WANG Yan, WU Xiaoxue, LIN Yuanyuan, LI Jianmei, XIE Yanhong. The effect of whey protein and ω-3 fatty acids combined with resistance exercise on the function of elderly sarcopenia patients[J]. Chinese Journal of General Practice, 2025, 23(12): 2064-2068. doi: 10.16766/j.cnki.issn.1674-4152.004292
shu

The effect of whey protein and ω-3 fatty acids combined with resistance exercise on the function of elderly sarcopenia patients

doi: 10.16766/j.cnki.issn.1674-4152.004292
  • 1.

    Department of Nephrology and Rheumatology, Lishui TCM Hospital Affiliated to Zhejiang Chinese Medical University, Lishui, Zhejiang 323000, China

Funds:

 2023KY005

  • Received Date: 2025-05-29
    Available Online: 2026-03-13
    Abstract
  •   Objective  With the global aging population, sarcopenia has become a significant health issue affecting the elderly. Current interventions primarily focus on nutritional supplementation and exercise training, but their effects are limited. This study explores the combined effects of whey protein, ω-3 fatty acids, and low-intensity resistance exercise on muscle mass, strength, walking speed, and daily living ability in elderly sarcopenia patients.  Methods  A total of 178 elderly patients diagnosed with sarcopenia between June 2022 and June 2024 at the Lishui Traditional Chinese Medicine Hospital of Zhejiang Chinese Medical University were selected. They were divided into the study group and control group using a random number table, with 89 cases in each group. The study group received whey protein and ω-3 fatty acid supplementation along with low-intensity resistance training, while the control group received conventional health education and low-intensity walking. Assessment indicators included muscle mass, muscle strength, walking speed, activities of daily living (ADL), and the short physical performance battery (SPPB).  Results  After treatment, the study group had higher muscle mass [(4.61±0.52) kg/m2] and muscle strength [(45.82±5.86) kg] than the control group [(3.52±0.45) kg/m2, (40.26±4.29) kg], and had a shorter walking speed [(4.12±0.55) s] compared to the control group [(5.67±0.69) s, P < 0.05]. The ADL score in the study group [(92.53±16.46) points] was higher than that in the control group [(81.51±11.26) points, t=5.213, P < 0.05]. The SPPB score in the study group [(10.16±1.46) points] was higher than that in the control group [(8.26±1.27) points, t=9.263, P < 0.05].  Conclusion  Whey protein combined with ω-3 fatty acids and low-intensity resistance exercise has a significant positive effect on the physical function and activities of daily living in elderly sarcopenia patients.

     

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