Volume 23 Issue 12
Dec.  2025
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SHEN Lianmei, SONG Mingxia, YUAN Ling. Analysis of risk factors of intrauterine distress in fetus[J]. Chinese Journal of General Practice, 2025, 23(12): 2088-2091. doi: 10.16766/j.cnki.issn.1674-4152.004298
Citation: SHEN Lianmei, SONG Mingxia, YUAN Ling. Analysis of risk factors of intrauterine distress in fetus[J]. Chinese Journal of General Practice, 2025, 23(12): 2088-2091. doi: 10.16766/j.cnki.issn.1674-4152.004298

Analysis of risk factors of intrauterine distress in fetus

doi: 10.16766/j.cnki.issn.1674-4152.004298
Funds:

 2023KY948

  • Received Date: 2025-02-19
    Available Online: 2026-03-13
  •   Objective  To analyze the risk factors of fetal intrauterine distress and their impact on neonatal prognosis, providing a basis for clinical intervention.  Methods  A total of 107 cases of intrauterine distress (observation group) and 107 normal pregnant women (control group) admitted to Hangzhou First People' s Hospital from January 2022 to December 2024 were enrolled, and the birth outcomes of neonates in the two groups were compared, and the risk factors affecting the occurrence of intrauterine distress were analyzed by logistic regression analysis and ROC working curve.  Results  Univariate analysis showed that abnormal umbilical cord blood flow, abnormal fetal heart rate, abnormal fetal movement, oligohydramnios, abnormal umbilical cord, placental abruption, gestational hypertension, and gestational diabetes mellitus were risk factors for fetal intrauterine distress (P < 0.05). Multivariate logistic regression analysis revealed that abnormal fetal heart rate, oligohydramnios, placental abruption, abnormal fetal movement, and gestational diabetes mellitus are independent risk factors for fetal distress (P < 0.05). ROC working curve analysis showed that the AUC of abnormal fetal heart rate, oligohydramnios, placental abruption, abnormal fetal movement and gestational diabetes mellitus was greater than 0.7, and the sensitivity (78.9%, 72.6%, 70.1%, 63.2%, 82.4%) and specificity (75.6%, 69.3%, 71.8%, 74.5%, 68.7%) were high. The 5-minute Apgar score was < 7 in the observation group, and the number of cases of neonatal asphyxia, hypoglycemia, hyperbilirubinemia, and fetal growth restriction were higher than those in the control group, and the perinatal mortality rate and Neonatal Intensive Care Unit (NICU) admission rate were also higher than those in the control group (P < 0.05).  Conclusion  Abnormal fetal heart rate, oligohydramnios, placental abruption, abnormal fetal movement, and gestational diabetes mellitus are risk factors for fetal intrauterine distress, and the above factors are likely to lead to adverse birth outcomes. Prenatal monitoring and perinatal care should be strengthened to improve perinatal outcomes.

     

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