Volume 24 Issue 1
Jan.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(1): 88-91
CHEN Siqiong, LI Wei, ZHONG Mengmeng, XUE Rong. Study on the influencing factors of functional constipation in children and its correlation with dietary habits/intestinal flora[J]. Chinese Journal of General Practice, 2026, 24(1): 88-91. doi: 10.16766/j.cnki.issn.1674-4152.004336
Citation: CHEN Siqiong, LI Wei, ZHONG Mengmeng, XUE Rong. Study on the influencing factors of functional constipation in children and its correlation with dietary habits/intestinal flora[J]. Chinese Journal of General Practice, 2026, 24(1): 88-91. doi: 10.16766/j.cnki.issn.1674-4152.004336
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Study on the influencing factors of functional constipation in children and its correlation with dietary habits/intestinal flora

doi: 10.16766/j.cnki.issn.1674-4152.004336

  • Department of Pediatrics, Wenzhou Hospital of Integrated Traditional and Western Medicine, Wenzhou, Zhejiang 325000, China

Funds:

 2025ZR203

  • Received Date: 2025-06-11
    Available Online: 2026-04-01
    Abstract
  •   Objective  To analyze the factors affecting functional constipation (FC) in children in Wenzhou area, and explore the correlation between FC occurrence and dietary habits and intestinal flora.  Methods  A total of 35 children with FC who were treated in the Department of Pediatrics of Wenzhou Hospital of Integrated Traditional and Western Medicine from December 2020 to December 2022 were selected as the FC group, and then 35 healthy children in the same period were selected as the control group. Questionnaires were conducted for all children and their guardians. The clinical data and intestinal flora characteristics of the two groups were compared. Multifactorial logistic regression was used to analyze the related factors affecting the incidence of FC in children, and Pearson correlation was used to analyze the correlation between correlation indicators and FC occurrence.  Results  Chao1 index, ACE index, and Shannon index in the FC group were lower than those in the control group (P < 0.05), while Simpson index was higher than those in the control group (P < 0.05). High frequency of vegetable and fruit intake (OR=0.768), high frequency of exercise (OR=0.494), high water intake (OR=0.206), and High flora Chao1 index (OR=0.931) were all protective factors affecting the incidence of FC in children. There were differences in the distribution of intestinal flora between the two groups. In the FC group, Prevotella and macroomonas were dominant, while in the control group, bifidobacterium and Lactobacillus were dominant (LDA>4log10).  Conclusion  High frequency of vegetable and fruit intake, high frequency of exercise, high water intake, and Chao1 index of bacterial flora were protective factors for the incidence of FC in children. The Prevotella, macroomonas, Bacteroides, and Enterococcus faecalis in intestinal flora may be related to the development of FC.

     

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