Volume 24 Issue 1
Jan.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(1): 109-112
LI Yahong, LI Songtao. The mediating role of self-efficacy and family support in the relationship between illness perception and treatment adherence in patients with major depressive disorder[J]. Chinese Journal of General Practice, 2026, 24(1): 109-112. doi: 10.16766/j.cnki.issn.1674-4152.004341
Citation: LI Yahong, LI Songtao. The mediating role of self-efficacy and family support in the relationship between illness perception and treatment adherence in patients with major depressive disorder[J]. Chinese Journal of General Practice, 2026, 24(1): 109-112. doi: 10.16766/j.cnki.issn.1674-4152.004341
shu

The mediating role of self-efficacy and family support in the relationship between illness perception and treatment adherence in patients with major depressive disorder

doi: 10.16766/j.cnki.issn.1674-4152.004341
  • 1.

    Department of Neurology, Shaoxing 7th People' s Hospital, Shaoxing, Zhejiang 312000, China

Funds:

 2024KY1735

  • Received Date: 2025-04-11
    Available Online: 2026-04-01
    Abstract
  •   Objective  To analyze the current status of treatment compliance in patients with major depressive disorder (MDD) and to validate the mediating model of self-efficacy and family support between illness perception and treatment compliance, based on cross-sectional survey data.  Methods  A total of 160 patients with MDD admitted to Shaoxing 7th People' s Hospital from August 2022 to August 2024 were selected by a convenience sampling method, and the general self-efficacy scale (GSES) and Morisky medical adherence scale (MMAS-8) were used for a questionnaire survey. The mediating role of self-efficacy and family support between disease perception and treatment compliance of MDD patients was analyzed through the Process plug-in.  Results  The MMAS-8 score of 156 (97.50%) valid questionnaires collected in this study was (5.72±1.36) points. Pearson correlation coefficient analysis showed that the MMAS-8 score was positively correlated with GSES and family support score (r=0.658, 0.514, P < 0.001). Bootstrap test showed that the indirect effect value was -0.152 (95% CI: -0.216 to -0.107) and the direct effect value was -0.233 (95% CI: -0.308 to -0.112).  Conclusion  The treatment compliance of patients with MDD needs to be improved. Disease perception can directly affect the treatment compliance of patients, and it can also indirectly affect the treatment compliance of patients through self-efficacy and family support.

     

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