Volume 24 Issue 2
Feb.  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(2): 255-258
LU Jingwen, WANG Rui, DONG Haojuan, SUN Huihui. Advantages of midline catheter infusion in the treatment of pediatric complex limb trauma and prediction of associated phlebitis[J]. Chinese Journal of General Practice, 2026, 24(2): 255-258. doi: 10.16766/j.cnki.issn.1674-4152.004373
Citation: LU Jingwen, WANG Rui, DONG Haojuan, SUN Huihui. Advantages of midline catheter infusion in the treatment of pediatric complex limb trauma and prediction of associated phlebitis[J]. Chinese Journal of General Practice, 2026, 24(2): 255-258. doi: 10.16766/j.cnki.issn.1674-4152.004373
shu

Advantages of midline catheter infusion in the treatment of pediatric complex limb trauma and prediction of associated phlebitis

doi: 10.16766/j.cnki.issn.1674-4152.004373
  • 1.

    Department of Orthopedics, Wuxi Ninth People ' s Hospital, Wuxi, Jiangsu 214000, China

Funds:

 BE2023292

  • Received Date: 2025-02-08
    Available Online: 2026-04-11
    Abstract
  •   Objective  Children with complex limb trauma often require prolonged intravenous therapy, during which peripheral venous catheters (PVCs) are associated with a high incidence of phlebitis. This study compared the efficacy of midline catheters (MCs) with PVCs and developed a predictive model for phlebitis to support clinical decision-making.  Methods  A retrospective analysis was conducted on 86 pediatric patients with complex limb trauma treated at the Department of Pediatric Orthopaedics, Wuxi Ninth People ' s Hospital, between January 2018 and June 2024. Patients were allocated to an observation group (MC, n=60) or a control group (PVC, n=26), and infusion-related risks and complications were compared. MC patients were further subdivided into a phlebitis subgroup (n=30) and a non-phlebitis subgroup (n=30). Risk variables were screened by Lasso regression, independent predictors were identified by logistic regression, and a prediction model was constructed using R software.  Results  The overall incidence of adverse events in the observation group was significantly lower than in the control group (P < 0.05). Phlebitis rates were 50.00%(30/60) with MC and 69.23% (18/26) with PVC (χ2=3.906, P=0.048). Logistic regression revealed that prolonged intravenous therapy duration (B=0.079, OR=1.082), extended catheter dwell time (B=0.163, OR=1.177), and higher drug irritancy (B=0.562, OR=1.755) were independent risk factors for phlebitis. The derived predictive model demonstrated excellent discriminative ability, with an AUC of 0.933 and an mean absolute error of 0.054.  Conclusion  MC and PVC exhibit similar first-attempt insertion success rates. However, MC offers longer dwell time, lower infusion-related risks, and fewer complications. The developed phlebitis prediction model accurately estimates the probability of phlebitis in children receiving MC, thereby facilitating evidence-based clinical decision-making.

     

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