A case report and literature review of cerebellar cognitive affective syndrome

YAO Hongyan; TANG Lian; WANG Qian; ZHANG Yumei

doi:10.16766/j.cnki.issn.1674-4152.004395

Volume 24 Issue 2

Feb. 2026

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YAO Hongyan, TANG Lian, WANG Qian, ZHANG Yumei. A case report and literature review of cerebellar cognitive affective syndrome[J]. Chinese Journal of General Practice, 2026, 24(2): 350-353. doi: 10.16766/j.cnki.issn.1674-4152.004395

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YAO Hongyan, TANG Lian, WANG Qian, ZHANG Yumei. A case report and literature review of cerebellar cognitive affective syndrome[J]. Chinese Journal of General Practice, 2026, 24(2): 350-353. doi: 10.16766/j.cnki.issn.1674-4152.004395

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A case report and literature review of cerebellar cognitive affective syndrome

doi: 10.16766/j.cnki.issn.1674-4152.004395

1.
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

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82372555

Received Date: 2025-06-21
Available Online: 2026-04-11

Abstract

Abstract

Clinically, patients suffering from cerebellar damage may present with cognitive impairment and affective dysregulation. These clinical manifestations are typically less severe than the cognitive deficits caused by cerebral damage and are often overlooked in clinical practice. This case report describes a patient with hemangioblastoma who developed mild cognitive impairment and affective dysregulation due to cerebellar or cerebellar circuit damage. The patient, a 43-year-old male, was admitted with a three-month history of gait instability, accompanied by slowed responses, anxiety and visual disturbances over the preceding 1.5 months. Following comprehensive neuropsychological assessments, a diagnosis of probable cerebellar cognitive affective syndrome (CCAS) was established. Following the administration of personalized functional rehabilitation, the patient exhibited a substantial improvement in symptoms. The objective of this report is to furnish clinical insights into the diagnosis and management of CCAS.
- Cerebellar cognitive affective syndrome,
- Hemangioblastoma,
- Universal cerebellar transform,
- Dysmetria of thought

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References(22)

References

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A case report and literature review of cerebellar cognitive affective syndrome

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