Volume 24 Issue 3
Mar.  2026
Turn off MathJax
Article Contents
ZHU Xuemei, TAO Jie, TAN Juan. Prevalence and clinical characteristics of chronic constipation in elderly patients with type 2 diabetes mellitus under family doctor contract management[J]. Chinese Journal of General Practice, 2026, 24(3): 460-463. doi: 10.16766/j.cnki.issn.1674-4152.004419
Citation: ZHU Xuemei, TAO Jie, TAN Juan. Prevalence and clinical characteristics of chronic constipation in elderly patients with type 2 diabetes mellitus under family doctor contract management[J]. Chinese Journal of General Practice, 2026, 24(3): 460-463. doi: 10.16766/j.cnki.issn.1674-4152.004419

Prevalence and clinical characteristics of chronic constipation in elderly patients with type 2 diabetes mellitus under family doctor contract management

doi: 10.16766/j.cnki.issn.1674-4152.004419
Funds:

 BJ24045

 LKM2022069

  • Received Date: 2025-02-19
    Available Online: 2026-06-02
  •   Objective  To investigate the prevalence of chronic constipation among community-dwelling elderly patients with type 2 diabetes mellitus (T2DM) and to analyze their clinical characteristics regarding metabolic profiles, lifestyle factors, and psychological status, aiming to provide scientific evidence for comprehensive interventions in this population.  Methods  A cross-sectional survey was conducted from June 2022 to June 2024 involving 293 elderly T2DM patients under contract management in Huaihai Community, Huaian City. Demographic characteristics, lifestyle, constipation symptoms, psychological scores, and biochemical indicators were collected and compared between the constipation and non-constipation groups.  Results  The prevalence of chronic constipation was 37.5% (110/293). Compared with the non-constipation group, the constipation group was older [(74.26±7.69) years vs. (70.66±6.25) years, P < 0.001] and had a longer diabetes duration [15.00(5.00, 20.00)years vs. 10.00(5.00, 18.50)years, P=0.016]. The rates of adequate coarse grain intake (47.71% vs. 61.67%, P=0.020), daily water intake (72.22% vs. 84.83%, P=0.010), sleep duration (38.89% vs. 52.51%, P=0.025), and physical activity (72.48% vs. 83.71%, P=0.022) were significantly lower in the constipation group. Additionally, the constipation group exhibited higher HbA1c levels [(7.82±1.70)% vs. (7.24±1.08)%, P=0.019] and anxiety/depression scores (P < 0.001), while estimated glomerular filtration rate was significantly lower [(79.97±21.81) mL/(min·1.73 m2) vs. (86.69±24.99) mL/(min·1.73 m2), P=0.023].  Conclusion  Community-dwelling elderly T2DM patients with chronic constipation are characterized by advanced age, longer diabetes duration, poor glycemic control, reduced renal function, significant anxiety and depression, and unhealthy lifestyle habits.

     

  • loading
  • [1]
    中国老年2型糖尿病防治临床指南编写组, 中国老年医学学会老年内分泌代谢分会, 中国老年保健医学研究会老年内分泌与代谢分会, 等. 中国老年2型糖尿病防治临床指南(2022年版)[J]. 中华内科杂志, 2022, 61(1): 12-50.

    Chinese Elderly Type 2 Diabetes Prevention and Treatment of Clinical Guidelines Writing Group, Geriatric Endocrinology and Metabolism Branch of Chinese Geriatric Society, Geriatric Endocrinology and Metabolism Branch of Chinese Geriatric Health Care Society, et al. Clinical guidelines for prevention and treatment of type 2 diabetes mellitus in the elderly in China (2022 edition)[J]. Chinese Journal of Internal Medicine, 2022, 61(1): 12-50.
    [2]
    YAN Y Q, WU T T, ZHANG M, et al. Prevalence, awareness and control of type 2 diabetes mellitus and risk factors in Chinese elderly population[J]. BMC Public Health, 2022, 22(1): 1382. DOI: 10.1186/s12889-022-13759-9.
    [3]
    DEB B, PRICHARD D O, BHARUCHA A E. Constipation and fecal incontinence in the elderly[J]. Curr Gastroenterol Rep, 2020, 22(11): 54. DOI: 10.1007/s11894-020-00791-1.
    [4]
    ZHANG T, ZULLO A R, JAMES H O, et al. The burden and treatment of chronic constipation among US nursing home residents[J]. J Am Med Dir Assoc, 2023, 24(8): 1247-1252.e1245. DOI: 10.1016/j.jamda.2023.05.006.
    [5]
    MOGESS W N, MIHRETIE T B, HABTE M L, et al. The magnitude of chronic constipation and associated factors among type 2 diabetic patients in Harar, Eastern Ethiopia[J]. Clin Diabetes Endocrinol, 2024, 10(1): 33. DOI: 10.1186/s40842-024-00188-3.
    [6]
    ABDU SEID M, DIRESS M, MOHAMMED A, et al. Chronic constipation and its associated factors in patients with type-2 diabetes: a multicenter cross-sectional study[J]. Diabetes Res Clin Pract, 2023, 204: 110905. DOI: 10.1016/j.diabres.2023.110905.
    [7]
    World Health Organization. Classification of diabetes mellitus, 2019[M]. Geneva: WHO Document Production Services, 2019.
    [8]
    DROSSMAN D A, HASLER W L. Rome Ⅳ-functional GI disorders: disorders of gut-brain interaction[J]. Gastroenterology, 2016, 150(6): 1257-1261. doi: 10.1053/j.gastro.2016.03.035
    [9]
    GONG B Y, MA H M, ZANG X Y, et al. Efficacy of cranial electrotherapy stimulation combined with biofeedback therapy in patients with functional constipation[J]. J Neurogastroenterol Motil, 2016, 22(3): 497-508. doi: 10.5056/jnm15089
    [10]
    唐丹. 简版老年抑郁量表(GDS-15)在中国老年人中的使用[J]. 中国临床心理学杂志, 2013, 21(3): 402-405.

    TANG D. Application of short form geriatric depression scale (GDS-15) in Chinese elderly[J]. Chinese Journal of Clinical Psycholog, 2013, 21(3): 402-405.
    [11]
    YURTDA?瘙塁G, ACAR-TEK N, AKBULUT G, et al. Risk factors for constipation in adults: a cross-sectional study[J]. J Am Coll Nutr, 2020, 39(8): 713-719. doi: 10.1080/07315724.2020.1727380
    [12]
    BHARUCHA A E, LACY B E. Mechanisms, evaluation, and management of chronic constipation[J]. Gastroenterology, 2020, 158(5): 1232-1249.e1233. DOI: 10.1053/j.gastro.2019.12.034.
    [13]
    MELDGAARD T, KELLER J, OLESEN A E, et al. Pathophysiology and management of diabetic gastroenteropathy[J]. Therap Adv Gastroenterol, 2019, 12: 1756284819852047. DOI: 10.1177/1756284819852047.
    [14]
    KORNUM D S, BERTOLI D, KUFAISHI H, et al. Transcutaneous vagal nerve stimulation for treating gastrointestinal symptoms in individuals with diabetes: a randomised, double-blind, sham-controlled, multicentre trial[J]. Diabetologia, 2024, 67(6): 1122-1137. doi: 10.1007/s00125-024-06129-0
    [15]
    MARTIN F P, COMINETTI O, BERGER B, et al. Metabolome-associated psychological comorbidities improvement in irritable bowel syndrome patients receiving a probiotic[J]. Gut Microbes, 2024, 16(1): 2347715. DOI: 10.1080/19490976.2024.2347715.
    [16]
    BALLOU S, KATON J, SINGH P, et al. Chronic diarrhea and constipation are more common in depressed individuals[J]Clin Gastroenterol Hepatol, 2019, 17(13): 2696-2703. doi: 10.1016/j.cgh.2019.03.046
    [17]
    俞汀, 朱锋, 林琳, 等. 合并上消化道症状对功能性便秘患者焦虑、抑郁及生活质量的影响[J]. 中华全科医学, 2022, 20(10): 1641-1644. doi: 10.16766/j.cnki.issn.1674-4152.002668

    YU T, ZHU F, LIN L, et al. Impact of combined upper gastrointestinal symptoms on anxiety, depression and quality of life of patients with functional constipation[J]. Chinese Journal of General Practice, 2022, 20(10): 1641-1644. doi: 10.16766/j.cnki.issn.1674-4152.002668
    [18]
    ADIBI P, ABDOLI M, DAGHAGHZADEH H, et al. Relationship between depression and constipation: results from a large cross-sectional study in adults[J]. Korean J Gastroenterol, 2022, 80(2): 77-84. doi: 10.4166/kjg.2022.038
    [19]
    GIMENES G M, PEREIRA J N B, BORGES DA SILVA E, et al. Intestinal motility dysfunction in Goto-Kakizaki rats: role of the myenteric plexus[J]. Cells, 2024, 13(19): 1626. DOI: 10.3390/cells13191626.
    [20]
    刘莉. 基于菌-肠-脑轴的肠肽与焦虑抑郁关系的研究进展[J]. 中华全科医学, 2022, 20(8): 1388-1391, 1399. doi: 10.16766/j.cnki.issn.1674-4152.002604

    LIU L. Research progress of intestinal peptides and the occurrence of anxiety and depression on the basis of the microbiota-gut-brain axis[J]. Chinese Journal of General Practice, 2022, 20(8): 1388-1391, 1399. doi: 10.16766/j.cnki.issn.1674-4152.002604
    [21]
    WEI L G, JI L Q, MIAO Y L, et al. Constipation in DM are associated with both poor glycemic control and diabetic complications: current status and future directions[J]. Biomed Pharmacother, 2023, 165: 115202. DOI: 10.1016/j.biopha.2023.115202.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(4)

    Article Metrics

    Article views (17) PDF downloads(2) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return