Volume 24 Issue 5
May  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(5): 841-845
LI Wenjuan, ZOU Qiuyu, ZHOU Fen, XIE Ling, XU Jing, ZHENG Yingqian, WANG Qiong. Effects of umbilical moxibustion combined with intermittent catheterization on lower urinary tract symptoms and bladder function in patients with neurogenic bladder following spinal cord injury[J]. Chinese Journal of General Practice, 2026, 24(5): 841-845. doi: 10.16766/j.cnki.issn.1674-4152.004504
Citation: LI Wenjuan, ZOU Qiuyu, ZHOU Fen, XIE Ling, XU Jing, ZHENG Yingqian, WANG Qiong. Effects of umbilical moxibustion combined with intermittent catheterization on lower urinary tract symptoms and bladder function in patients with neurogenic bladder following spinal cord injury[J]. Chinese Journal of General Practice, 2026, 24(5): 841-845. doi: 10.16766/j.cnki.issn.1674-4152.004504
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Effects of umbilical moxibustion combined with intermittent catheterization on lower urinary tract symptoms and bladder function in patients with neurogenic bladder following spinal cord injury

doi: 10.16766/j.cnki.issn.1674-4152.004504

  • Department of Acupuncture, Massage and Rehabilitation Center, the First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China

Funds:

 D202319017905

 B2024074

  • Received Date: 2025-09-02
    Available Online: 2026-10-23
    Abstract
  •   Objective  To evaluate the effects of combining umbilical moxibustion with intermittent catheterization on lower urinary tract symptoms (LUTS) and bladder function in patients with neurogenic bladder (NB) following spinal cord injury (SCI), aiming to provide the optimization of management strategies for post-SCI NB.  Methods  A total of 84 NB patients following SCI admitted to the First Hospital of Hunan University of Chinese Medicine from April 2023 to April 2025 were enrolled and randomly divided into a combination group (n=42) and a control group (n=42) using the sealed envelope method. The control group received intermittent catheterization, while the combination group additionally received umbilical moxibustion for 4 weeks. Clinical efficacy and safety were evaluated. Urination parameters (maximum voided volume per void, single void volume over 24 h, 24-hour voiding frequency), bladder function [maximum bladder capacity (MCC), bladder compliance (BC), maximum urinary flow rate (Qmax), post-void residual volume (PVR)], urinary tract infection indicators (urinary white blood cell count), and LUTS [international LUTS symptom score] were assessed before and after treatment.  Results  The total effective rate in the combination group was 92.86% (39/42), which was higher than that in the control group [71.43% (30/42), P < 0.05]. After 4 weeks of treatment, both groups showed increased in maximum voided volume, single void volume over 24 h, MCC, BC, and Qmax, with greater improvements in the combination group (P < 0.05). Both groups also exhibited reduced 24-hour voiding frequency, PVR, urinary white blood cell count, and LUTS scores, with lower values in the combination group (P < 0.05).  Conclusion  Umbilical moxibustion combined with intermittent catheterization significantly improves bladder function and LUTS, reduces urinary tract infections, and demonstrates good safety in NB patients following SCI.

     

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    • References(28)
  • [1]
    项俊, 严刘斐, 夏福昕, 等. 生物反馈联合电刺激治疗脊髓损伤后神经源性膀胱的疗效观察[J]. 中国康复, 2020, 35(5): 254-255.

    XIANG J, YAN L F, XIAO F X, et al. Observation on the curative effect of biofeedback combined with electrical stimulation in the treatment of neurogenic bladder after spinal cord injury[J]. Chinese Journal of Rehabilitation, 2020, 35(5): 254-255.
    [2]
    DENYS P, CHARTIER-KASTLER E, EVEN A, et al. How to treat neurogenic bladder and sexual dysfunction after spinal cord lesion[J]. Rev Neurol (Paris), 2021, 177(5): 589-593. doi: 10.1016/j.neurol.2020.07.013
    [3]
    中华医学会泌尿外科学分会尿控学组. 间歇性导尿临床应用中国专家共识[J]. 中华泌尿外科杂志, 2024, 45(9): 654-657.

    Group of Urinary Continence, Chinese Society of Urology. Chinese expert consensus on the clinical application of intermittent catheterization[J]. Chinese Journal of Urology, 2024, 45(9): 654-657.
    [4]
    郑芝, 邬真, 颜林志, 等. 间歇导尿法联合盆底肌康复训练在宫颈癌患者术后康复中的应用[J]. 中华全科医学, 2023, 21(4): 713-716. doi: 10.16766/j.cnki.issn.1674-4152.002966

    ZHENG Z, WU Z, YAN L Z, et al. Effect of intermittent catheterization combined with pelvic floor muscle rehabilitation training on postoperative rehabilitation in patients with cervical cancer[J]. Chinese Journal of General Practice, 2023, 21(4): 713-716. doi: 10.16766/j.cnki.issn.1674-4152.002966
    [5]
    刘瑞琪, 魏丽娟, 杨洪涛. 杨洪涛教授从三焦气机辨治癃闭经验初探[J]. 中国中西医结合肾病杂志, 2021, 22(4): 287-288.

    LIU R Q, WEI L J, YANG H T. Exploration of Professor Yang Hongtao's experience in treating retention of urine from the perspective of triple energizer qi movement[J]. Chinese Journal of Integrated Traditional and Western nephrology, 2021, 22(4): 287-288.
    [6]
    王志磊, 张娟, 高树中, 等. 脐灸疗法治疗泌尿生殖系统疾病研究进展[J]. 中华中医药杂志, 2021, 36(4): 2210-2212.

    WANG Z L, ZHANG J, GAO S Z, et al. Research progress of umbilical moxibustion in the treatment of genitourinary diseases[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2021, 36(4): 2210-2212.
    [7]
    RUPP R, BIERING-SORENSEN F, BURNS S P, et al. International standards for neurological classification of spinal cord injury: revised 2019[J]. Top Spinal Cord Inj Rehabil, 2021, 27(2): 1-22.
    [8]
    陈忠, 崔喆, 双卫兵. 神经源性膀胱[M]. 北京: 人民卫生出版社, 2009: 219-220.

    CHEN Z, CAI Z, SHUANG W B. Neurogenic Bladder[M]. Beijing: People's Medical Publishing House, 2009: 219-220.
    [9]
    国家中医药管理局. 中医病证诊断疗效标准[M]. 南京: 南京大学出版社, 1994: 49.

    National Administration of Traditional Chinese Medicine (NATCM) Diagnostic criteria of TCM syndrome[M]. Nanjing: Nanjing University Press, 1994: 49.
    [10]
    WITJES J A, BRUINS H M, CATHOMAS R, et al. European association of urology guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2020 guidelines[J]. Eur Urol, 2021, 79(1): 82-104. doi: 10.1016/j.eururo.2020.03.055
    [11]
    国家市场监督管理总局, 国家标准化管理委员会. GB/T 21709.9-2023针灸技术操作规范第9部分: 艾灸[S]. 北京: 中国标准出版社, 2023.

    The State Administration for Market Regulation and the Standardization Administration. GB/T 21709.9-2023 Technical specifications of acupuncture and moxibustion Part 9: Moxibustion[S]. Beijing: Standards Press of China, 2023.
    [12]
    南登昆, 王宁华, 励建安. 康复医学[M]. 4版. 北京: 人民卫生出版社, 2008: 280-283.

    NAN D K, WANG N H, LI J A. Rehabilitation Medicine[M]. 4th ed. Beijing: People's Medical Publishing House, 2008: 280-283.
    [13]
    OKAMURA K, KIMURA K, MIZUNO H, et al. Core lower urinary tract symptom score questionnaire: a psychometric analysis[J]. Int J Urol, 2014, 21(11): 1151-1154. doi: 10.1111/iju.12522
    [14]
    杜晓梅, 沈录峰, 钱金荣, 等. 盆底康复仪联合间歇导尿在脑卒中神经源性尿失禁患者护理中的应用[J]. 护理实践与研究, 2022, 19(7): 1081-1084.

    DU X M, SHEN L F, QIAN J R, et al. Application of pelvic floor rehabilitation instrument combined with intermittent catheterization in the nursing of neurogenic urinary incontinence patients caused by stroke[J]. Nursing Practice and Research, 2022, 19(7): 1081-1084.
    [15]
    袁丹, 钟潇, 王明松, 等. 脊髓损伤神经源性膀胱患者间歇导尿期间尿路感染病原菌分布及影响因素[J]. 中华实验和临床感染病杂志(电子版), 2024, 18(4): 229-236.

    YUAN D, ZHONG X, WANG M S, et al. Distribution and influencing factors of urinary tract infection during intermittent catheterization in patients with spinal cord injury and neurogenic bladder[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2024, 18(4): 229-236.
    [16]
    周丽琼, 王瑞香, 范春花, 等. 神经源性膀胱患者自我间歇清洁导尿依从性影响因素的质性研究[J]. 中国医药导报, 2020, 17(30): 72-75.

    ZHOU L Q, WANG R X, FAN C H, et al. Qualitative study on the influencing factors of compliance with self-inter-mittent cleansing catheterization in patients with neurogenic bladder[J]. China Medical Herald, 2020, 17(30): 72-75.
    [17]
    韦慧麟, 任亚锋, 张芝兰, 等. 电针和艾灸治疗脊髓损伤后神经源性膀胱疗效差异: 随机对照试验[J]. 中国针灸, 2023, 43(9): 1036-1041.

    WEI H L, REN Y F, ZHANG Z L, et al. Efficacy differences between electroacupuncture and moxibustion for neurogenie bladder after spinal cord injury: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2023, 43(9): 1036-1041.
    [18]
    王能, 冯琦钒, 林晓伟, 等. 针灸联合金匮肾气丸对脊髓损伤后神经源性膀胱尿潴留患者影响的临床研究[J]. 世界中西医结合杂志, 2020, 15(3): 524-527, 531.

    WANG N, FENG Q F, LIN X W, et al. Effect of acupuncture combined with Jingui Shenqi Pills on patients with neurogenicbladder and urine retention after spinal cord injur[J]. World Journal of Integrated Traditional and Western Medicine, 2020, 15(3): 524-527, 531.
    [19]
    STABILE A, GIGANTI F, ROSEENKRANTZ A B, et al. Multiparametric MRI for prostate cancer diagnosis: current status and future directions[J]. Nat Rev Urol, 2020, 17(1): 41-61. doi: 10.1038/s41585-019-0212-4
    [20]
    金芳全, 樊成虎. 基于"肾合膀胱"论治脊髓损伤后神经源性膀胱[J]. 湖北民族大学学报(医学版), 2023, 40(1): 69-72.

    JIN F Q, FAN C H. Treatment of neurogenic bladder after spinal cord injury based on the theory of "kidney merging with bladder"[J]. Journal of Hubei Minzu University (Medical Edition), 2023, 40(1): 69-72.
    [21]
    骆名智, 余义. 神经源性膀胱患者康复期间并发尿路感染的危险因素与病原学特征分析[J]. 抗感染药学, 2024, 21(4): 415-418.

    LUO M Z, YU Y. Analysis of risk factors and etiological characteristics of concurrent urinary tract infection during rehabilitation of patients with neurogenic bladder[J]. Anti Infection Pharmacy, 2024, 21(4): 415-418.
    [22]
    王东利, 王学乾, 王蕊, 等. 基于子午流注理论择时脐疗治疗脊髓损伤后神经源性膀胱: 随机对照试验[J]. 中国针灸, 2023, 43(11): 1246-1250.

    WANG D L, WANG X Q, WANG R, et al. Timing umbilical therapy in treatment of neurogenic bladder after spinal cord injury based onmidnight-noon and ebb-flow doctrine: a randomized controlled trial[J]. Chinese Acupuncture & Moxibustion, 2023, 43(11): 1246-1250.
    [23]
    李冰, 王永福, 任亚锋, 等. 艾灸对骶髓损伤后逼尿肌无反射型神经源性膀胱大鼠膀胱组织M2、P2X3受体的影响[J]. 中国针灸, 2022, 42(3): 291-297.

    LI B, WANG Y F, REN Y F, et al. Effect of moxibustion on M2 and P2X3 receptors of bladder tissue in rats with neurogenic bladderof detrusor areflexia after lumbar-sacral spinal cord injury[J]. Chinese Acupuncture & Moxibustion, 2022, 42(3): 291-297.
    [24]
    沈英飞, 张灿, 张灿芬, 等. 隔附子饼灸联合膀胱功能训练治疗不完全脊髓损伤尿潴留的临床研究[J]. 中华中医药杂志, 2020, 35(7): 3758-3761.

    SHEN Y F, ZHANG C, ZHANG C F, et al. Clinical study of aconite moxibustion combined with bladder function training fortreating urinary retention after incomplete spinal cord injury[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2020, 35(7): 3758-3761.
    [25]
    魏炜, 杨志新, 王天雨, 等. 艾灸"相对穴"对大鼠脊髓损伤后神经源性膀胱及内质网应激途径的影响[J]. 中国针灸, 2022, 42(4): 413-418.

    WEI W, YANG Z X, WANG T Y, et al. Effect of moxibustion at "oppositely-located points" on neurogenic bladder after spinal cordinjury and endoplasmic reticulum stress pathway in rats[J]. Chinese Acupuncture & Moxibustion, 2022, 42(4): 413-418.
    [26]
    杨健濠, 卢美静, 赵彩娇, 等. 灵龟八法按时开穴灸对衰老大鼠免疫功能及核因子-κB信号通路的影响[J]. 针刺研究, 2020, 45(12): 980-984.

    YANG J H, LU M J, ZHAO C J, et al. Effect of moxibustion at "acupoint-open on-time" on immune function and nuclear factor-κB signaling pathway in aging rats[J]. Acupuncture Research, 2020, 45(12): 980-984.
    [27]
    黄积仓, 毛亚兰, 裴强强, 等. 艾灸神阙穴(CV8)、济生肾气丸联合西药对慢性肾脏病3~4期疗效及免疫功能的影响[J]. 天津中医药, 2021, 38(8): 1041-1045.

    HUANG J C, MAO Y L, PEI Q Q, et al. Effect of moxibustion at Shenque(CV8), oral administration Jisheng Shenqi Pill and Western medicine on the efficacy andimmune function of chronic kidney disease stage 3-4[J]. Tianjin Journal of Traditional Chinese Medicine, 2021, 38(8): 1041-1045.
    [28]
    谢衣恒, 张芮, 郭海洋, 等. 附子多糖的提取纯化、结构表征及其对RAW 264.7巨噬细胞免疫活性的影响[J]. 中国抗生素杂志, 2024, 49(12): 1329-1337.

    XIE Y H, ZHANG R, GUO H Y, et al. Extraction, purification, structural characterization of polysaccharide from AconitiLateralis Radix Praeparata and its biological evaluation on immune activity ofRAW 264.7 cells[J]. Chinese Journal of Antibiotics, 2024, 49(12): 1329-1337.
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