Volume 24 Issue 5
May  2026
Turn off MathJax
Article Contents
Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(5): 863-865
PENG Tingting, XU Jian, KONG Lingti. Analysis of antibiotic use in clinical departments of a hospital[J]. Chinese Journal of General Practice, 2026, 24(5): 863-865. doi: 10.16766/j.cnki.issn.1674-4152.004509
Citation: PENG Tingting, XU Jian, KONG Lingti. Analysis of antibiotic use in clinical departments of a hospital[J]. Chinese Journal of General Practice, 2026, 24(5): 863-865. doi: 10.16766/j.cnki.issn.1674-4152.004509
shu

Analysis of antibiotic use in clinical departments of a hospital

doi: 10.16766/j.cnki.issn.1674-4152.004509
  • 1.

    Department of Spine Surgery, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui 233004, China

Funds:

 YQYB2024043

 2025AHGXZK31521

  • Received Date: 2025-05-21
    Available Online: 2026-10-23
    Abstract
  •   Objective  To investigate and analyze the basic situation of antimicrobial use among inpatients in a hospital, with the aim of identifying the general patterns and issues related to antimicrobial usage, promoting standardized and rational antimicrobial use in clinical settings, and ensuring patients medication safety.  Methods  Data on antimicrobial consumption among inpatients in various clinical departments in the hospital from 2019 to 2023 were collected. The average length of hospital stay (days) and the total number of discharged patients during the same period were obtained. The antimicrobial use density (AUD) and antimicrobial usage rate (AUR) among inpatients were calculated. Statistical analysis was conducted to rank each department and each antimicrobial agent according to their AUD values.  Results  The overall AUR among inpatients was 42.99%. The five departments with the highest AUR were Emergency Surgery (90.38%), Urology (87.66%), Otorhinolaryngology (86.57%), Gynecology (85.53%), and ICU (85.45%). The three departments with the lowest AUR were Oncology Surgery (8.72%), Oncology Medicine (7.16%), and Ophthalmology (5.59%). The overall AUD among inpatients was 45.38. The five departments with the highest AUD were the ICU (216.41), Emergency Surgery (211.77), Emergency Medicine (137.05), Pediatrics (97.35), and Hematology (97.30). The three departments with the lowest AUD were Rehabilitation Medicine (7.41), Oncology Medicine (7.26), and Ophthalmology (5.07). The five antimicrobial agents with the highest AUD were levofloxacin (7.29), cefodizime (6.63), cefuroxime (3.43), cefathiamidine for injection (2.51), and cefoperazone sodium and sulbactam sodium for injection (2.35). The three agents with the lowest AUD were azithromycin for injection (0.77), cefoxitin sodium for injection (0.72), and cefazolin sodium for injection (0.66).  Conclusion  The AUD is excessively high in this hospital, indicating the need to further strengthen antimicrobial management to promote the rational use of antibiotics.

     

    • FullText(HTML)
  • loading
    • References(16)
  • [1]
    THEODOSIOU A A, JONES C E, READ R C, et al. Microbiotoxicity: antibiotic usage and its unintended harm to the microbiome[J]. Curr Opin Infect Dis, 2023, 36(5): 371-378. doi: 10.1097/QCO.0000000000000945
    [2]
    王雪, 汪雨贺, 高山, 等. 某三级教学医院呼吸重症病房抗菌药物管理核查表的临床应用及评价[J]. 中华全科医学, 2022, 20(10): 1792-1796. doi: 10.16766/j.cnki.issn.1674-4152.002704

    WANG X, WANG Y H, GAO S, et al. Evaluation and implementation of an antimicrobial stewardship checklist in a respiratory ICU ward in a tertiary teaching hospital[J]. Chinese Journal of General Practice, 2022, 20(10): 1792-1796. doi: 10.16766/j.cnki.issn.1674-4152.002704
    [3]
    AGARWAL M, ESTRADA L V, GRACNER T, et al. Nursing home antibiotic stewardship policy and antibiotics use: 2013—2017[J]. J Am Med Dir Assoc, 2022, 23(3), 482-487. doi: 10.1016/j.jamda.2021.06.031
    [4]
    CHEN B, YANG X, ZHAN M M, et al. Dietary tangeretin improved antibiotic-associated diarrhea in mice by enhancing the intestinal barrier function, regulating the gut microbiota, and metabolic homeostasis[J]. Food Funct, 2023, 14(24): 10731-10746. doi: 10.1039/D3FO02998K
    [5]
    SPEROTTO F, FRANCE K, GOBBO M, et al. Antibiotic prophylaxis and infective endocarditis incidence following invasive dental procedures: a systematic review and meta-analysis[J]. JAMA Cardiol, 2024, 9(7): 599-610. doi: 10.1001/jamacardio.2024.0873
    [6]
    DING G D, ZHANG X B, VINTURACHE A, et al. Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia[J]. Eur J Pediatr, 2024, 183(7): 3001-3011. doi: 10.1007/s00431-024-05519-1
    [7]
    MCCANN P, KRUOCH Z, LOPEZ S, et al. Interventions for dry eye: an overview of systematic reviews[J]. JAMA Ophthalmol, 2024, 142(1): 58-74. doi: 10.1001/jamaophthalmol.2023.5751
    [8]
    RAJAN S M, SHRESTHA B, AATI S, et al. Evaluation of antibacterial efficacy of high-intensity focused ultrasound versus photodynamic therapy against enterococcus faecalis-infected root canals[J]. Ultrasound Med Biol, 2023, 49(8): 1875-1881. doi: 10.1016/j.ultrasmedbio.2023.04.018
    [9]
    FAN L, YANG M, HAN Y T, et al. Drug recommendation for optimization on treatment outcome for MDR/RR-TB based on a multi-center, large scale, retrospective cohort study in China[J]. Expert Rev Anti Infect Ther, 2024, 22(5): 353-363. doi: 10.1080/14787210.2024.2303032
    [10]
    ECKMANN C, AGHDASSI S J S, BRINKMANN A, et al. Perioperative antibiotic prophylaxis-indications and modalities for the prevention of postoperative wound infection[J]. Dtsch Arztebl Int, 2024, 121(7): 233-242.
    [11]
    窦欲晓, 胡学锋, 许健. 某综合医院神经外科围手术期抗菌药物合理性分析[J]. 中华全科医学, 2023, 21(10): 1686-1688. doi: 10.16766/j.cnki.issn.1674-4152.003201

    DOU Y X, HU X F, XU J. Rationality analysis of perioperative antibiotics in neurosurgery of a general hospital[J]. Chinese Journal of General Practice, 2023, 21(10): 1686-1688. doi: 10.16766/j.cnki.issn.1674-4152.003201
    [12]
    LIEU A C, JUN J H, AFSHARI N A. Intracameral antibiotics during cataract surgery: efficacy, safety, and cost-benefit considerations[J]. Curr Opin Ophthalmol, 2024, 35(1): 50-56. doi: 10.1097/ICU.0000000000001010
    [13]
    LIN M M, YANG S S, HUANG Q Y, et al. Effect and mechanism of Qingre Huashi decoction on drug-resistant Helicobacter pylori[J]. World J Gastroenterol, 2024, 30(24): 3086-3105. doi: 10.3748/wjg.v30.i24.3086
    [14]
    GROENEN H, BONTEKONING N, JALALZADEH H, et al. Incisional wound irrigation for the prevention of surgical site infection: a systematic review and network meta-analysis[J]. JAMA Surg, 2024, 159(7): 792-800. doi: 10.1001/jamasurg.2024.0775
    [15]
    ZAGALES I, SAUDER M, SELVAKUMAR S, et al. Comparing outcomes of appendectomy versus non-operative antibiotic therapy for acute appendicitis: a systematic review and meta-analysis of randomized clinical trials[J]. Am Surg, 2023, 89(6): 2644-2655. doi: 10.1177/00031348221114045
    [16]
    HARTOFILIS L, RIGGINS J K. Abdominal pain: update on emergency department management of appendicitis and diverticulitis[J]. Emerg Med Pract, 2024, 26(10): 1-28.
    • Relative Articles
    • Supplements(0)
    • Cited By

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(3)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (10) PDF downloads(3) Cited by()
    Proportional views
    Related

    Address：No. 287, Changhuai Road, Bengbu, Anhui Province, 233004, P.R.ChinaphoneNo：0552-3066635； 0552-3051890Email：zhqkyx@163.com

    Copyright © Chinese Journal of General Practice皖ICP备2020018345号-2

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return