Volume 24 Issue 5
May  2026
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Article Navigation >  Chinese Journal of General Practice  > 2026  >  24(5): 866-868
CHEN Yingqiu, WANG Runping, ZHENG Xiaofen, DAI Xiaozhong, CHEN Aiwu. The mediating effect of positive perceptions on the relationship between caregiver readiness and disease uncertainty among caregivers of children with leukemia undergoing PICC catheterization[J]. Chinese Journal of General Practice, 2026, 24(5): 866-868. doi: 10.16766/j.cnki.issn.1674-4152.004510
Citation: CHEN Yingqiu, WANG Runping, ZHENG Xiaofen, DAI Xiaozhong, CHEN Aiwu. The mediating effect of positive perceptions on the relationship between caregiver readiness and disease uncertainty among caregivers of children with leukemia undergoing PICC catheterization[J]. Chinese Journal of General Practice, 2026, 24(5): 866-868. doi: 10.16766/j.cnki.issn.1674-4152.004510
shu

The mediating effect of positive perceptions on the relationship between caregiver readiness and disease uncertainty among caregivers of children with leukemia undergoing PICC catheterization

doi: 10.16766/j.cnki.issn.1674-4152.004510

  • Department of Pediatric Hematology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

Funds:

 Y20210286

 LGF21G020002

  • Received Date: 2025-05-24
    Available Online: 2026-10-23
    Abstract
  •   Objective  To explore the current situation of caregiver readiness, positive perceptions, and illness uncertainty among family caregivers of children with leukemia undergoing PICC catheterization, and to analyze the relationships among the three variables, thereby providing evidence for clinical improvement aimed at reducing caregivers' sense of disease uncertainty.  Methods  Convenience sampling method was used to select the family caregivers. A total of 109 leukemia patients with PICC catheterization who admitted to the Department of Pediatric Hematology, the Second Affiliated Hospital of Wenzhou Medical University from January 2024 to June 2024 were recruited. General information form, prent's perception uncertainty in illness scale (PPUS), positive aspects of care giver scale (PAC), and care preparedness scale (CPS) were used for investigation. Pearson correlation analysis was applied to explore the correlations among the three variables.  Results  The mean PPUS score was (89.54±12.98) points, the PAC score was (25.18±5.27) points, and the CPS scale score was (24.07±3.38) points. There was a positive correlation between caregiver readiness and positive perception (r=0.495, P < 0.01). While caregiver readiness and positive perception were both negatively correlated with disease uncertainty (r=-0.385, -0.408, P < 0.01). Positive perceptions partially mediated the relationship between caregiver readiness and disease uncertainty, with a mediating effect value of 0.179 (95% CI: 0.122- 0.235, P < 0.001), accounting for 46.22% of the total effect.  Conclusion  Positive perceptions paly a partial mediating role in the relationship between caregiver readiness and disease uncertainty among caregivers of children with leukemia undergoing PICC catheterization. Medical staff can alleviate the uncertainty of illness among caregivers of sick children by improving their caregiver preparedness and enhancing their positive perceptions.

     

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