Volume 21 Issue 7
Jul.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(7): 1184-1187
LI Guanfei, ZHANG Xunjuan, PANG Meng, LI Song. Prevalence and associated factors of chronic orthostatic intolerance in communities[J]. Chinese Journal of General Practice, 2023, 21(7): 1184-1187. doi: 10.16766/j.cnki.issn.1674-4152.003080
Citation: LI Guanfei, ZHANG Xunjuan, PANG Meng, LI Song. Prevalence and associated factors of chronic orthostatic intolerance in communities[J]. Chinese Journal of General Practice, 2023, 21(7): 1184-1187. doi: 10.16766/j.cnki.issn.1674-4152.003080
shu

Prevalence and associated factors of chronic orthostatic intolerance in communities

doi: 10.16766/j.cnki.issn.1674-4152.003080

  • Department of Neurology, Jilin Provincial People ' s Hospital, Changchun, Jilin 130021, China

Funds:

 20200403121SF

  • Received Date: 2023-01-15
    Available Online: 2023-08-28
    Abstract
  •   Objective  To investigate the prevalence and associated factors of chronic orthostatic intolerance (OI) in community-dwelling middle-aged and elderly people.  Methods  From January to September 2021, a random cluster sample of 546 registered residents aged ≥40 years in three community health services in Changchun was conducted. Data included medical history, questionnaire and blood pressure in supine and standing positions. SPSS 26.0 software was used for descriptive statistical analysis. Factors associated with OI were analyzed by multivariate logistic regression models.  Results  The overall prevalence of OI was 15.8%(86/546), and among the subtypes, the prevalence of orthostatic hypotension (OH), postural orthostatic tachycardia syndrome (POTS) and orthostatic hypertension (OHT) were 10.6%(58/546), 0.7%(4/546) and 4.4%(24/546), respectively. The prevalence of OH was significantly higher than the other two subtypes(χ2=56.840, P < 0.001). Stratified by age, the prevalence of OI tended to increase with age(χ2=7.919, P=0.048), with the highest prevalence in those aged ≥70 years old(20.6%, 28/136). Multi-factor logistic regression analysis showed that age≥60 years, hypertension, and supine systolic blood pressure ≥140 mmHg (1 mmHg=0.133 kPa) in the prone position were independent risk factors for chronic OI.  Conclusion  There is a high prevalence of chronic OI in the middle-aged and elderly population in communities. OH is the main clinical type. Elderly people, hypertension and supine systolic hypertension are at high risk of developing chronic OI. Therefore, prevention and control of OI should be strengthened in key populations.

     

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