Volume 21 Issue 7
Jul.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(7): 1202-1205
HE Yadong, SUN Yixue, PANG Qing, LI Dongdong, LI Yang. Application value of superb microvascular imaging-based vascular index to quantitatively assess liver fibrosis[J]. Chinese Journal of General Practice, 2023, 21(7): 1202-1205. doi: 10.16766/j.cnki.issn.1674-4152.003084
Citation: HE Yadong, SUN Yixue, PANG Qing, LI Dongdong, LI Yang. Application value of superb microvascular imaging-based vascular index to quantitatively assess liver fibrosis[J]. Chinese Journal of General Practice, 2023, 21(7): 1202-1205. doi: 10.16766/j.cnki.issn.1674-4152.003084
shu

Application value of superb microvascular imaging-based vascular index to quantitatively assess liver fibrosis

doi: 10.16766/j.cnki.issn.1674-4152.003084
  • 1.

    Department of Ultrasound, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 KJ2020A0582

 AHCM2022Z003

 Byycx22141

  • Received Date: 2023-03-02
    Available Online: 2023-08-28
    Abstract
  •   Objective  The Superb microvascular imaging (SMI) -based vascular index (SMI-VI) technique was applied to evaluate neovascularization in patients with hepatic fibrosis, to provide a new repeatable and quantitative assessment of the extent of liver fibrosis.  Methods  The SMI technique was used to measure the subcapsular vascular index of 93 patients with liver fibrosis and 25 healthy normal subjects who were treated in the First Affiliated Hospital of Bengbu Medical College from September 2020 to August 2021, to investigate the relationship between vascular index and the degree of liver fibrosis, and to compare the difference of the vascular index between patients with mild liver fibrosis and healthy normal subjects. The ROC curve of the vascular index was plotted to determine the optimal cut-off value for each stage of hepatic fibrosis.  Results  SMI-VI was positively correlated with the level of liver fibrosis (r= 0.754, P < 0.001). SMI-VI in patients with mild liver fibrosis was 10.40 (8.28, 13.63), which was higher than that in healthy normal subjects [8.60 (6.85, 10.10)], and the difference was statistically significant (P < 0.05). The cut-off values of SMI-VI for the diagnosis of significant liver fibrosis, progressive liver fibrosis, and cirrhosis were 10.65, 12.25 and 14.55, with corresponding areas under the curve of 0.86, 0.89 and 0.95, sensitivity of 88%, 86% and 85% and specificity of 70%, 72% and 90%, respectively.  Conclusion  The vascular index based on SMI technology has important clinical applications as it can quantitatively assess the degree of liver fibrosis non-invasively and easily by analyzing the number of vessels under the liver capsule.

     

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