Volume 21 Issue 8
Aug.  2023
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Article Navigation >  Chinese Journal of General Practice  > 2023  >  21(8): 1315-1318
ZHANG Mengyu, DUAN Shimiao, WU Ye, GUO Ziwen, LI Wei, JIANG Hao. Study on differences in target delineation methods for lung tumors using on four-dimensional CT[J]. Chinese Journal of General Practice, 2023, 21(8): 1315-1318. doi: 10.16766/j.cnki.issn.1674-4152.003111
Citation: ZHANG Mengyu, DUAN Shimiao, WU Ye, GUO Ziwen, LI Wei, JIANG Hao. Study on differences in target delineation methods for lung tumors using on four-dimensional CT[J]. Chinese Journal of General Practice, 2023, 21(8): 1315-1318. doi: 10.16766/j.cnki.issn.1674-4152.003111
shu

Study on differences in target delineation methods for lung tumors using on four-dimensional CT

doi: 10.16766/j.cnki.issn.1674-4152.003111
  • 1.

    Department of Radiotherapy, the First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui 233004, China

Funds:

 2020b07030008

 BYKY2019077ZD

  • Received Date: 2023-01-11
    Available Online: 2023-09-13
    Abstract
  •   Objective  Based on four dimensional CT (4DCT) images of patients with lung tumors in different parts, the study compares which target delineation method is more efficient.  Methods  A total of 130 patients with lung tumors, who underwent 4DCT simulation scans at the First Affiliated Hospital of Bengbu Medical College from October 2019 to December 2021 were selected. The doctor delineated the gross tumor volume (GTV) targets in 10 phases of 4DCT, and IGTV10 was obtained by fusion. IGTVMIP, IGTVAIP and IGTV2 were obtained based on maximum density projection (MIP), average density projection (AIP) images, 0% and 50% time-phase of 4DCT. The above delineation methods were compared in terms of volume and centroid displacement.  Results  The ratios of IGTVMIP, IGTVAIP and IGTV2 to IGTV10 in the upper lobe group were 1.00, 0.98 and 0.99, respectively (P=0.143, < 0.001, < 0.001). The ratios for the middle and lower lobe groups were 0.99, 0.96 and 0.98, respectively (P=0.603, < 0.001, < 0.001). There was no significant difference in the degree of mutual inclusion between IGTV10 and IGTVMIP in the upper lung lobe group (P>0.05), while there was a significant difference in the degree of mutual inclusion between IGTV10, IGTVAIP and IGTV2 in the upper lung lobe group (all P < 0.05). The degree of mutual inclusion of IGTV10, IGTVMIP, IGTVAIP and IGTV2 in the middle and lower lung lobe group was significantly different (all P < 0.05).  Conclusion  The motion information contained in the 10 time-fused images is significantly greater than that of the AIP images and the 0%+50% fused images, but close to that of the MIP images. The location of the tumor should also be considered when using MIP images to delineate the target area.

     

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